Basic Information
Gene ID 4779 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name NFE2L1; HBZ17, NRF1, TCF11
Full Name Nuclear factor erythroid 2-related factor 1
Organism Homo sapiens [9606]

Cross Reference
UniProt Q14494 UniGene Hs.514284
PDB NULL OMIM 163260
KEGG hsa:4779 UCSC uc002ina.4

Protein Interactions
DIP NULL
IntAct Q14494
MINT NULL
STRING 9606.ENSP00000355190

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000354855 Gene3D G3DSA:1.10.880.10 IPR008917 599 672 9.70e-37 Transcription factor, Skn-1-like, DNA-binding domain
ENSP00000354855 Pfam PF03131 IPR004826 626 717 3.50e-17 Basic leucine zipper domain, Maf-type
ENSP00000354855 ProSitePatterns PS00036 IPR004827 659 674 - Basic-leucine zipper domain
ENSP00000354855 ProSiteProfiles PS50217 IPR004827 654 717 0.00e-00 Basic-leucine zipper domain
ENSP00000354855 SMART SM00338 IPR004827 652 716 3.30e-11 Basic-leucine zipper domain
ENSP00000354855 SUPERFAMILY SSF47454 IPR008917 610 678 0.00e-00 Transcription factor, Skn-1-like, DNA-binding domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000354855 PF03131 1.6e-17 bZIP_Maf bZIP Maf transcription factor
ENSP00000354855 PF00170 1.5e-05 bZIP_1 bZIP transcription factor
ENSP00000354855 PF07716 7.5e-05 bZIP_2 Basic region leucine zipper

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000354855 GO:0005634 cellular_component nucleus
ENSP00000354855 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000354855 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100120332 7029 Acyrthosiphon pisum 100168358
6087 Hydra magnipapillata 100209530 28377 Anolis carolinensis 100560659
30195 Bombus terrestris 100645181 132113 Bombus impatiens 100744774
143995 Megachile rotundata 100882485 34638 Metaseiulus occidentalis 100906298
9597 Pan paniscus 100988657 9555 Papio anubis 101004761
39432 Saimiri boliviensis 101035377 9685 Felis catus 101084497
8090 Oryzias latipes 101155725 8083 Xiphophorus maculatus 102227561
7897 Latimeria chalumnae 102363898 10090 Mus musculus 18025
7227 Drosophila melanogaster 42743 7463 Apis florea 100871742
13735 Pelodiscus sinensis 102453399 9358 Choloepus hoffmanni ENSCHOG00000011948
51511 Ciona savignyi ENSCSAVG00000003043 10020 Dipodomys ordii ENSDORG00000000715
69293 Gasterosteus aculeatus ENSGACG00000003904 61853 Nomascus leucogenys ENSNLEG00000002415
9978 Ochotona princeps ENSOPRG00000003683 132908 Pteropus vampyrus ENSPVAG00000002566
9478 Tarsius syrichta ENSTSYG00000011468 8364 Xenopus tropicalis ENSXETG00000021958
7668 Strongylocentrotus purpuratus 574577 7070 Tribolium castaneum 657062
9544 Macaca mulatta 695404 7460 Apis mellifera 725081
9646 Ailuropoda melanoleuca ENSAMEG00000004881 9615 Canis familiaris ENSCAFG00000002865
7719 Ciona intestinalis ENSCING00000003373 10141 Cavia porcellus ENSCPOG00000021825
9361 Dasypus novemcinctus ENSDNOG00000012919 9365 Erinaceus europaeus ENSEEUG00000009322
9371 Echinops telfairi ENSETEG00000014473 9031 Gallus gallus ENSGALG00000011937
9595 Gorilla gorilla ENSGGOG00000002268 8049 Gadus morhua ENSGMOG00000003077
9785 Loxodonta africana ENSLAFG00000018523 9315 Macropus eugenii ENSMEUG00000011499
9103 Meleagris gallopavo ENSMGAG00000001269 30608 Microcebus murinus ENSMICG00000014716
59463 Myotis lucifugus ENSMLUG00000005024 13616 Monodelphis domestica ENSMODG00000012375
9669 Mustela putorius furo ENSMPUG00000015301 9258 Ornithorhynchus anatinus ENSOANG00000000315
9986 Oryctolagus cuniculus ENSOCUG00000022298 30611 Otolemur garnettii ENSOGAG00000025191
8128 Oreochromis niloticus ENSONIG00000006191 9813 Procavia capensis ENSPCAG00000006292
7757 Petromyzon marinus ENSPMAG00000002714 9601 Pongo abelii ENSPPYG00000008890
9598 Pan troglodytes ENSPTRG00000022631 10116 Rattus norvegicus ENSRNOG00000008830
42254 Sorex araneus ENSSARG00000002776 43179 Ictidomys tridecemlineatus ENSSTOG00000013664
37347 Tupaia belangeri ENSTBEG00000009449 59729 Taeniopygia guttata ENSTGUG00000014715
99883 Tetraodon nigroviridis ENSTNIG00000010098 31033 Takifugu rubripes ENSTRUG00000012259
9739 Tursiops truncatus ENSTTRG00000016554 30538 Vicugna pacos ENSVPAG00000010116