Basic Information
Gene ID 4799 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name NFX1; NFX2
Full Name Transcriptional repressor NF-X1
Organism Homo sapiens [9606]

Cross Reference
UniProt Q12986 UniGene Hs.413074
PDB NULL OMIM 603255
KEGG hsa:4799 UCSC uc003zsq.3

Protein Interactions
DIP NULL
IntAct Q12986
MINT NULL
STRING 9606.ENSP00000368856

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000368856 Pfam PF01422 IPR000967 506 524 1.00e-04 Zinc finger, NF-X1-type
ENSP00000368856 Pfam PF01422 IPR000967 567 586 1.50e-04 Zinc finger, NF-X1-type
ENSP00000368856 Pfam PF01422 IPR000967 632 655 9.50e-08 Zinc finger, NF-X1-type
ENSP00000368856 Pfam PF01422 IPR000967 721 740 5.20e-06 Zinc finger, NF-X1-type
ENSP00000368856 Pfam PF01422 IPR000967 832 854 2.40e-05 Zinc finger, NF-X1-type
ENSP00000368856 Pfam PF01424 IPR001374 1002 1059 2.80e-18 Single-stranded nucleic acid binding R3H
ENSP00000368856 ProSitePatterns PS01359 IPR019786 358 408 - Zinc finger, PHD-type, conserved site
ENSP00000368856 ProSiteProfiles PS50016 IPR019787 355 411 0.00e-00 Zinc finger, PHD-finger
ENSP00000368856 ProSiteProfiles PS50089 IPR001841 358 409 0.00e-00 Zinc finger, RING-type
ENSP00000368856 ProSiteProfiles PS51061 IPR001374 994 1062 0.00e-00 Single-stranded nucleic acid binding R3H
ENSP00000368856 SMART SM00184 IPR001841 358 408 2.50e-05 Zinc finger, RING-type
ENSP00000368856 SMART SM00393 IPR001374 983 1061 9.70e-29 Single-stranded nucleic acid binding R3H
ENSP00000368856 SMART SM00438 IPR000967 453 471 4.00e-06 Zinc finger, NF-X1-type
ENSP00000368856 SMART SM00438 IPR000967 506 525 7.60e-07 Zinc finger, NF-X1-type
ENSP00000368856 SMART SM00438 IPR000967 567 586 4.90e-06 Zinc finger, NF-X1-type
ENSP00000368856 SMART SM00438 IPR000967 632 655 2.00e-07 Zinc finger, NF-X1-type
ENSP00000368856 SMART SM00438 IPR000967 694 713 1.70e-02 Zinc finger, NF-X1-type
ENSP00000368856 SMART SM00438 IPR000967 721 740 9.80e-08 Zinc finger, NF-X1-type
ENSP00000368856 SMART SM00438 IPR000967 778 797 1.70e-02 Zinc finger, NF-X1-type
ENSP00000368856 SMART SM00438 IPR000967 832 854 1.70e-07 Zinc finger, NF-X1-type
ENSP00000368856 SMART SM00438 IPR000967 863 884 7.30e-05 Zinc finger, NF-X1-type

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000368856 PF01422 3.9e-31 zf-NF-X1 NF-X1 type zinc finger
ENSP00000368856 PF01424 1.2e-18 R3H R3H domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000368856 GO:0005634 cellular_component nucleus
ENSP00000368856 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000368856 GO:0008270 molecular_function zinc ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100116742 7463 Apis florea 100868679
9669 Mustela putorius furo 101684482 6087 Hydra magnipapillata 100203326
61853 Nomascus leucogenys 100590740 400682 Amphimedon queenslandica 100642041
30195 Bombus terrestris 100647077 132113 Bombus impatiens 100746423
143995 Megachile rotundata 100883051 34638 Metaseiulus occidentalis 100908089
9597 Pan paniscus 100976210 9555 Papio anubis 101020878
39432 Saimiri boliviensis 101027617 6239 Caenorhabditis elegans 175902
10116 Rattus norvegicus 313166 7227 Drosophila melanogaster 34888
9598 Pan troglodytes 465042 10090 Mus musculus 74164
7668 Strongylocentrotus purpuratus 755253 9646 Ailuropoda melanoleuca ENSAMEG00000007472
7719 Ciona intestinalis ENSCING00000004746 9483 Callithrix jacchus ENSCJAG00000008142
51511 Ciona savignyi ENSCSAVG00000005762 9361 Dasypus novemcinctus ENSDNOG00000002079
10020 Dipodomys ordii ENSDORG00000001989 9796 Equus caballus ENSECAG00000021305
9365 Erinaceus europaeus ENSEEUG00000001694 9371 Echinops telfairi ENSETEG00000001427
69293 Gasterosteus aculeatus ENSGACG00000004560 7897 Latimeria chalumnae ENSLACG00000000769
9315 Macropus eugenii ENSMEUG00000012002 9103 Meleagris gallopavo ENSMGAG00000009425
30608 Microcebus murinus ENSMICG00000012124 59463 Myotis lucifugus ENSMLUG00000011069
13616 Monodelphis domestica ENSMODG00000003990 9258 Ornithorhynchus anatinus ENSOANG00000002524
9986 Oryctolagus cuniculus ENSOCUG00000008957 9813 Procavia capensis ENSPCAG00000006913
7757 Petromyzon marinus ENSPMAG00000003556 9601 Pongo abelii ENSPPYG00000019136
13735 Pelodiscus sinensis ENSPSIG00000008420 132908 Pteropus vampyrus ENSPVAG00000011479
42254 Sorex araneus ENSSARG00000014320 9823 Sus scrofa ENSSSCG00000010993
37347 Tupaia belangeri ENSTBEG00000004560 31033 Takifugu rubripes ENSTRUG00000009872
9478 Tarsius syrichta ENSTSYG00000004125 9739 Tursiops truncatus ENSTTRG00000010576
8364 Xenopus tropicalis ENSXETG00000014997 7070 Tribolium castaneum 659177
9615 Canis familiaris ENSCAFG00000001848 9358 Choloepus hoffmanni ENSCHOG00000009225
9685 Felis catus ENSFCAG00000007905 9595 Gorilla gorilla ENSGGOG00000006751
8049 Gadus morhua ENSGMOG00000006198 9785 Loxodonta africana ENSLAFG00000012270
30611 Otolemur garnettii ENSOGAG00000000775 8128 Oreochromis niloticus ENSONIG00000006192
9978 Ochotona princeps ENSOPRG00000009816 59729 Taeniopygia guttata ENSTGUG00000007055
30538 Vicugna pacos ENSVPAG00000001305 8083 Xiphophorus maculatus ENSXMAG00000001963