Basic Information
Gene ID 5079 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name PAX5
Full Name Paired box protein Pax-5
Organism Homo sapiens [9606]

Cross Reference
UniProt Q02548 UniGene Hs.654464
PDB 1MDM OMIM 613065
KEGG hsa:5079 UCSC uc010mlp.1

Protein Interactions
DIP NULL
IntAct Q02548
MINT NULL
STRING 9606.ENSP00000350844

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000350844 Gene3D G3DSA:1.10.10.10 IPR011991 19 84 7.20e-42 Winged helix-turn-helix DNA-binding domain
ENSP00000350844 Gene3D G3DSA:1.10.10.10 IPR011991 85 146 4.80e-37 Winged helix-turn-helix DNA-binding domain
ENSP00000350844 Pfam PF00292 IPR001523 16 140 5.00e-73 Paired domain
ENSP00000350844 Pfam PF12403 IPR022130 282 390 3.90e-52 Paired-box protein 2 C-terminal
ENSP00000350844 PRINTS PR00027 IPR001523 20 35 7.40e-45 Paired domain
ENSP00000350844 PRINTS PR00027 IPR001523 38 56 7.40e-45 Paired domain
ENSP00000350844 PRINTS PR00027 IPR001523 58 75 7.40e-45 Paired domain
ENSP00000350844 PRINTS PR00027 IPR001523 76 93 7.40e-45 Paired domain
ENSP00000350844 ProSitePatterns PS00034 IPR001523 50 66 - Paired domain
ENSP00000350844 ProSiteProfiles PS51057 IPR001523 16 142 0.00e-00 Paired domain
ENSP00000350844 SMART SM00351 IPR001523 16 140 1.60e-98 Paired domain
ENSP00000350844 SUPERFAMILY SSF46689 IPR009057 18 140 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000350844 PF00292 0 PAX 'Paired box' domain
ENSP00000350844 PF12403 0 Pax2_C Paired-box protein 2 C terminal
ENSP00000350844 PF13384 4.2e-05 HTH_23 Homeodomain-like domain
ENSP00000350844 PF13551 7.7e-05 HTH_29 Winged helix-turn helix

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000350844 GO:0006351 biological_process transcription, DNA-templated
ENSP00000350844 GO:0005634 cellular_component nucleus
ENSP00000350844 GO:0003677 molecular_function DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
6087 Hydra magnipapillata 100192231 9483 Callithrix jacchus 100389113
61853 Nomascus leucogenys 100586040 400682 Amphimedon queenslandica 100632785
10029 Cricetulus griseus 100752440 7668 Strongylocentrotus purpuratus 100892688
34638 Metaseiulus occidentalis 100899851 9305 Sarcophilus harrisii 100923405
9597 Pan paniscus 100972924 9595 Gorilla gorilla 101124378
43179 Ictidomys tridecemlineatus 101962397 6239 Caenorhabditis elegans 187062
9601 Pongo abelii 100457719 39432 Saimiri boliviensis 101046586
9669 Mustela putorius furo 101670700 7955 Danio rerio 30425
9598 Pan troglodytes 744540 28377 Anolis carolinensis ENSACAG00000014063
9913 Bos taurus ENSBTAG00000021566 10141 Cavia porcellus ENSCPOG00000009987
30608 Microcebus murinus ENSMICG00000017679 59463 Myotis lucifugus ENSMLUG00000012652
13616 Monodelphis domestica ENSMODG00000002720 9258 Ornithorhynchus anatinus ENSOANG00000007579
9813 Procavia capensis ENSPCAG00000004660 9823 Sus scrofa ENSSSCG00000010556
37347 Tupaia belangeri ENSTBEG00000007983 9478 Tarsius syrichta ENSTSYG00000001117
8364 Xenopus tropicalis ENSXETG00000006547 8083 Xiphophorus maculatus ENSXMAG00000012680
9646 Ailuropoda melanoleuca ENSAMEG00000010127 9615 Canis familiaris ENSCAFG00000009709
9358 Choloepus hoffmanni ENSCHOG00000003521 10020 Dipodomys ordii ENSDORG00000015818
9796 Equus caballus ENSECAG00000000551 9365 Erinaceus europaeus ENSEEUG00000012531
9371 Echinops telfairi ENSETEG00000002360 9685 Felis catus ENSFCAG00000001628
69293 Gasterosteus aculeatus ENSGACG00000016112 9031 Gallus gallus ENSGALG00000016431
8049 Gadus morhua ENSGMOG00000006294 9785 Loxodonta africana ENSLAFG00000028851
9315 Macropus eugenii ENSMEUG00000011758 9103 Meleagris gallopavo ENSMGAG00000003186
9544 Macaca mulatta ENSMMUG00000019639 9986 Oryctolagus cuniculus ENSOCUG00000012281
8128 Oreochromis niloticus ENSONIG00000008952 9978 Ochotona princeps ENSOPRG00000000734
8090 Oryzias latipes ENSORLG00000005326 13735 Pelodiscus sinensis ENSPSIG00000003215
132908 Pteropus vampyrus ENSPVAG00000000054 10116 Rattus norvegicus ENSRNOG00000024729
42254 Sorex araneus ENSSARG00000002067 59729 Taeniopygia guttata ENSTGUG00000007215
99883 Tetraodon nigroviridis ENSTNIG00000005085 31033 Takifugu rubripes ENSTRUG00000008891
9739 Tursiops truncatus ENSTTRG00000006049