Basic Information
Gene ID 59328 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Smad5; Madh5
Full Name Mothers against decapentaplegic homolog 5
Organism Rattus norvegicus [10116]

Cross Reference
UniProt Q9R1V3 UniGene Rn.146857
PDB NULL OMIM NULL
KEGG rno:59328 UCSC RGD:620158

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 10116.ENSRNOP00000016704

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_067724 Gene3D G3DSA:2.60.200.10 IPR017855 263 465 1.30e-96 SMAD domain-like
NP_067724 Gene3D G3DSA:3.90.520.10 IPR013019 5 144 8.60e-62 MAD homology, MH1
NP_067724 PANTHER PTHR13703 IPR013790 1 465 0.00e-00 Dwarfin
NP_067724 Pfam PF03165 IPR003619 32 132 4.80e-42 MAD homology 1, Dwarfin-type
NP_067724 Pfam PF03166 IPR001132 266 442 1.60e-77 SMAD domain, Dwarfin-type
NP_067724 ProSiteProfiles PS51075 IPR013019 13 137 0.00e-00 MAD homology, MH1
NP_067724 ProSiteProfiles PS51076 IPR001132 271 465 0.00e-00 SMAD domain, Dwarfin-type
NP_067724 SMART SM00523 IPR003619 26 135 4.80e-71 MAD homology 1, Dwarfin-type
NP_067724 SMART SM00524 IPR001132 269 441 1.10e-107 SMAD domain, Dwarfin-type
NP_067724 SUPERFAMILY SSF49879 IPR008984 235 456 0.00e-00 SMAD/FHA domain
NP_067724 SUPERFAMILY SSF56366 IPR013019 14 132 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_067724 PF03166 0 MH2 MH2 domain
NP_067724 PF03165 2.29953e-42 MH1 MH1 domain
NP_067724 PF10401 1.1e-06 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
NP_067724 GO:0001657 biological_process ureteric bud development
NP_067724 GO:0002051 biological_process osteoblast fate commitment
NP_067724 GO:0006351 biological_process transcription, DNA-templated
NP_067724 GO:0006468 biological_process protein phosphorylation
NP_067724 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
NP_067724 GO:0030509 biological_process BMP signaling pathway
NP_067724 GO:0045669 biological_process positive regulation of osteoblast differentiation
NP_067724 GO:0051216 biological_process cartilage development
NP_067724 GO:0060348 biological_process bone development
NP_067724 GO:0071773 biological_process cellular response to BMP stimulus
NP_067724 GO:1901522 biological_process positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
NP_067724 GO:0005634 cellular_component nucleus
NP_067724 GO:0005667 cellular_component transcription factor complex
NP_067724 GO:0005737 cellular_component cytoplasm
NP_067724 GO:0000979 molecular_function RNA polymerase II core promoter sequence-specific DNA binding
NP_067724 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_067724 GO:0046872 molecular_function metal ion binding