Basic Information
Gene ID 63950 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name DMRTA2; DMRT5
Full Name Doublesex- and mab-3-related transcription factor A2
Organism Homo sapiens [9606]

Cross Reference
UniProt Q96SC8 UniGene Hs.334481
PDB NULL OMIM 614804
KEGG hsa:63950 UCSC uc010ona.2

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9606.ENSP00000383909

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000383909 Gene3D G3DSA:4.10.1040.10 IPR001275 65 112 2.20e-27 DM DNA-binding domain
ENSP00000383909 PANTHER PTHR12322 IPR026607 28 542 0.00e-00 DMRT/protein doublesex/protein male abnormal 3
ENSP00000383909 Pfam PF00751 IPR001275 66 112 3.40e-23 DM DNA-binding domain
ENSP00000383909 Pfam PF03474 IPR005173 313 351 1.20e-17 DMRTA motif
ENSP00000383909 ProSitePatterns PS40000 IPR001275 70 99 - DM DNA-binding domain
ENSP00000383909 ProSiteProfiles PS50809 IPR001275 70 117 0.00e-00 DM DNA-binding domain
ENSP00000383909 SMART SM00301 IPR001275 66 119 1.70e-31 DM DNA-binding domain
ENSP00000383909 SUPERFAMILY SSF46934 IPR009060 310 355 0.00e-00 UBA-like
ENSP00000383909 SUPERFAMILY SSF82927 IPR001275 64 112 0.00e-00 DM DNA-binding domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000383909 PF00751 2.4e-23 DM DM DNA binding domain
ENSP00000383909 PF03474 7.6e-18 DMA DMRTA motif

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000383909 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000383909 GO:0005634 cellular_component nucleus
ENSP00000383909 GO:0003677 molecular_function DNA binding
ENSP00000383909 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000383909 GO:0043565 molecular_function sequence-specific DNA binding
ENSP00000383909 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100394865 30195 Bombus terrestris 100648249
34638 Metaseiulus occidentalis 100900775 9597 Pan paniscus 100975415
39432 Saimiri boliviensis 101042107 6239 Caenorhabditis elegans 184287
7668 Strongylocentrotus purpuratus 581867 13616 Monodelphis domestica 100016059
7029 Acyrthosiphon pisum 100163006 6087 Hydra magnipapillata 100204042
10224 Saccoglossus kowalevskii 100374921 9823 Sus scrofa 100517627
8128 Oreochromis niloticus 100692595 7463 Apis florea 100870783
143995 Megachile rotundata 100880032 9555 Papio anubis 100998209
8083 Xiphophorus maculatus 102221849 10090 Mus musculus 242620
7227 Drosophila melanogaster 43495 9598 Pan troglodytes 469318
7070 Tribolium castaneum 664586 9913 Bos taurus ENSBTAG00000033352
9615 Canis familiaris ENSCAFG00000030863 9358 Choloepus hoffmanni ENSCHOG00000000826
7719 Ciona intestinalis ENSCING00000005905 10020 Dipodomys ordii ENSDORG00000015486
9796 Equus caballus ENSECAG00000022281 9365 Erinaceus europaeus ENSEEUG00000010425
9685 Felis catus ENSFCAG00000008588 8049 Gadus morhua ENSGMOG00000000998
7897 Latimeria chalumnae ENSLACG00000012046 9785 Loxodonta africana ENSLAFG00000021953
59463 Myotis lucifugus ENSMLUG00000006249 9669 Mustela putorius furo ENSMPUG00000007160
9986 Oryctolagus cuniculus ENSOCUG00000001019 30611 Otolemur garnettii ENSOGAG00000012178
8090 Oryzias latipes ENSORLG00000004153 9601 Pongo abelii ENSPPYG00000001366
13735 Pelodiscus sinensis ENSPSIG00000013048 132908 Pteropus vampyrus ENSPVAG00000005723
10116 Rattus norvegicus ENSRNOG00000008105 9305 Sarcophilus harrisii ENSSHAG00000006920
43179 Ictidomys tridecemlineatus ENSSTOG00000024624 37347 Tupaia belangeri ENSTBEG00000015360
99883 Tetraodon nigroviridis ENSTNIG00000015486 31033 Takifugu rubripes ENSTRUG00000001824
9478 Tarsius syrichta ENSTSYG00000011375 9739 Tursiops truncatus ENSTTRG00000015206
8364 Xenopus tropicalis ENSXETG00000002846 28377 Anolis carolinensis ENSACAG00000007289
9646 Ailuropoda melanoleuca ENSAMEG00000017464 10141 Cavia porcellus ENSCPOG00000024909
51511 Ciona savignyi ENSCSAVG00000010848 9371 Echinops telfairi ENSETEG00000000334
69293 Gasterosteus aculeatus ENSGACG00000011145 9595 Gorilla gorilla ENSGGOG00000013269
9315 Macropus eugenii ENSMEUG00000008505 30608 Microcebus murinus ENSMICG00000003290
9544 Macaca mulatta ENSMMUG00000019055 9258 Ornithorhynchus anatinus ENSOANG00000002763
9978 Ochotona princeps ENSOPRG00000013060 9813 Procavia capensis ENSPCAG00000006879
7757 Petromyzon marinus ENSPMAG00000003668 30538 Vicugna pacos ENSVPAG00000007442