Basic Information | |||
Gene ID | 657515 | ||
Gene Name | ecr-a | ||
Full Name | Ecdysone receptor (Isoform A) | ||
Organism | Tribolium castaneum [7070] |
Cross Reference | |||
UniProt | A1JUG3 | UniGene | Tca.11903 |
PDB | 2NXX | OMIM | NULL |
KEGG | tca:657515 | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | A1JUG3 |
MINT | MINT-5223773 |
STRING | 7070.A1JUG3 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_001107650 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 242 | 283 | 9.20e-79 | Nuclear hormone receptor, ligand-binding |
NP_001107650 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 334 | 546 | 9.20e-79 | Nuclear hormone receptor, ligand-binding |
NP_001107650 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 188 | 241 | 3.00e-27 | Zinc finger, NHR/GATA-type |
NP_001107650 | Pfam | PF00104 | IPR000536 | 354 | 523 | 8.40e-32 | Nuclear hormone receptor, ligand-binding, core |
NP_001107650 | Pfam | PF00105 | IPR001628 | 187 | 254 | 3.20e-31 | Zinc finger, nuclear hormone receptor-type |
NP_001107650 | PRINTS | PR00047 | IPR001628 | 188 | 204 | 1.40e-18 | Zinc finger, nuclear hormone receptor-type |
NP_001107650 | PRINTS | PR00047 | IPR001628 | 204 | 219 | 1.40e-18 | Zinc finger, nuclear hormone receptor-type |
NP_001107650 | PRINTS | PR00047 | IPR001628 | 237 | 245 | 1.40e-18 | Zinc finger, nuclear hormone receptor-type |
NP_001107650 | PRINTS | PR00047 | IPR001628 | 245 | 253 | 1.40e-18 | Zinc finger, nuclear hormone receptor-type |
NP_001107650 | PRINTS | PR00398 | IPR001723 | 249 | 259 | 1.10e-26 | Steroid hormone receptor |
NP_001107650 | PRINTS | PR00398 | IPR001723 | 361 | 382 | 1.10e-26 | Steroid hormone receptor |
NP_001107650 | PRINTS | PR00398 | IPR001723 | 382 | 398 | 1.10e-26 | Steroid hormone receptor |
NP_001107650 | PRINTS | PR00398 | IPR001723 | 449 | 464 | 1.10e-26 | Steroid hormone receptor |
NP_001107650 | PRINTS | PR00398 | IPR001723 | 506 | 523 | 1.10e-26 | Steroid hormone receptor |
NP_001107650 | PRINTS | PR01283 | IPR003069 | 176 | 187 | 3.40e-69 | Ecdysteroid receptor |
NP_001107650 | PRINTS | PR01283 | IPR003069 | 254 | 263 | 3.40e-69 | Ecdysteroid receptor |
NP_001107650 | PRINTS | PR01283 | IPR003069 | 314 | 339 | 3.40e-69 | Ecdysteroid receptor |
NP_001107650 | PRINTS | PR01283 | IPR003069 | 346 | 365 | 3.40e-69 | Ecdysteroid receptor |
NP_001107650 | PRINTS | PR01283 | IPR003069 | 408 | 421 | 3.40e-69 | Ecdysteroid receptor |
NP_001107650 | PRINTS | PR01283 | IPR003069 | 436 | 454 | 3.40e-69 | Ecdysteroid receptor |
NP_001107650 | PRINTS | PR01283 | IPR003069 | 508 | 525 | 3.40e-69 | Ecdysteroid receptor |
NP_001107650 | PRINTS | PR01283 | IPR003069 | 527 | 545 | 3.40e-69 | Ecdysteroid receptor |
NP_001107650 | ProSitePatterns | PS00031 | IPR001628 | 188 | 214 | - | Zinc finger, nuclear hormone receptor-type |
NP_001107650 | ProSiteProfiles | PS51030 | IPR001628 | 185 | 260 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
NP_001107650 | SMART | SM00399 | IPR001628 | 185 | 256 | 4.10e-45 | Zinc finger, nuclear hormone receptor-type |
NP_001107650 | SMART | SM00430 | IPR000536 | 360 | 518 | 3.80e-41 | Nuclear hormone receptor, ligand-binding, core |
NP_001107650 | SUPERFAMILY | SSF48508 | IPR008946 | 313 | 545 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_001107650 | PF00104 | 5.3e-32 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
NP_001107650 | PF00105 | 1.2e-31 | zf-C4 | Zinc finger, C4 type (two domains) |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_001107650 | GO:0006351 | biological_process | transcription, DNA-templated |
NP_001107650 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
NP_001107650 | GO:0035076 | biological_process | ecdysone receptor-mediated signaling pathway |
NP_001107650 | GO:0043401 | biological_process | steroid hormone mediated signaling pathway |
NP_001107650 | GO:0005634 | cellular_component | nucleus |
NP_001107650 | GO:0003677 | molecular_function | DNA binding |
NP_001107650 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
NP_001107650 | GO:0003707 | molecular_function | steroid hormone receptor activity |
NP_001107650 | GO:0004884 | molecular_function | ecdysteroid hormone receptor activity |
NP_001107650 | GO:0005496 | molecular_function | steroid binding |
NP_001107650 | GO:0008270 | molecular_function | zinc ion binding |
NP_001107650 | GO:0043565 | molecular_function | sequence-specific DNA binding |
NP_001107650 | GO:0046872 | molecular_function | metal ion binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9796 | Equus caballus | 100052399 | 9646 | Ailuropoda melanoleuca | 100474551 |
28377 | Anolis carolinensis | 100567692 | 61853 | Nomascus leucogenys | 100605954 |
30195 | Bombus terrestris | 100646757 | 9785 | Loxodonta africana | 100673961 |
10029 | Cricetulus griseus | 100756988 | 143995 | Megachile rotundata | 100883359 |
39432 | Saimiri boliviensis | 101027381 | 31033 | Takifugu rubripes | 101078607 |
8083 | Xiphophorus maculatus | 102221658 | 9258 | Ornithorhynchus anatinus | 100074592 |
7425 | Nasonia vitripennis | 100119033 | 7029 | Acyrthosiphon pisum | 100160393 |
59729 | Taeniopygia guttata | 100219563 | 10224 | Saccoglossus kowalevskii | 100313647 |
9601 | Pongo abelii | 100453246 | 9103 | Meleagris gallopavo | 100545018 |
8128 | Oreochromis niloticus | 100702741 | 132113 | Bombus impatiens | 100749603 |
7463 | Apis florea | 100872217 | 34638 | Metaseiulus occidentalis | 100908536 |
9597 | Pan paniscus | 100971327 | 9555 | Papio anubis | 100997292 |
9595 | Gorilla gorilla | 101126697 | 9669 | Mustela putorius furo | 101692562 |
43179 | Ictidomys tridecemlineatus | 101976065 | 7897 | Latimeria chalumnae | 102366585 |
13735 | Pelodiscus sinensis | 102462146 | 10090 | Mus musculus | 22259 |
7227 | Drosophila melanogaster | 35540 | 9031 | Gallus gallus | 395221 |
9823 | Sus scrofa | 397553 | 7460 | Apis mellifera | 406084 |
7668 | Strongylocentrotus purpuratus | 574588 | 10116 | Rattus norvegicus | 58852 |
9544 | Macaca mulatta | 695618 | 9913 | Bos taurus | ENSBTAG00000013596 |
9615 | Canis familiaris | ENSCAFG00000008824 | 9483 | Callithrix jacchus | ENSCJAG00000004439 |
10141 | Cavia porcellus | ENSCPOG00000013362 | 10020 | Dipodomys ordii | ENSDORG00000007747 |
9365 | Erinaceus europaeus | ENSEEUG00000003283 | 9371 | Echinops telfairi | ENSETEG00000000415 |
9685 | Felis catus | ENSFCAG00000002528 | 69293 | Gasterosteus aculeatus | ENSGACG00000017167 |
9315 | Macropus eugenii | ENSMEUG00000002853 | 59463 | Myotis lucifugus | ENSMLUG00000017646 |
13616 | Monodelphis domestica | ENSMODG00000019906 | 9986 | Oryctolagus cuniculus | ENSOCUG00000002095 |
30611 | Otolemur garnettii | ENSOGAG00000012593 | 9978 | Ochotona princeps | ENSOPRG00000009497 |
8090 | Oryzias latipes | ENSORLG00000001286 | 9813 | Procavia capensis | ENSPCAG00000016194 |
9598 | Pan troglodytes | ENSPTRG00000003560 | 132908 | Pteropus vampyrus | ENSPVAG00000001768 |
37347 | Tupaia belangeri | ENSTBEG00000000492 | 99883 | Tetraodon nigroviridis | ENSTNIG00000009590 |
9739 | Tursiops truncatus | ENSTTRG00000014149 | 9606 | Homo sapiens | 9971 |
9358 | Choloepus hoffmanni | ENSCHOG00000001621 | 7719 | Ciona intestinalis | ENSCING00000007203 |
7955 | Danio rerio | ENSDARG00000057741 | 8049 | Gadus morhua | ENSGMOG00000005399 |
30608 | Microcebus murinus | ENSMICG00000007066 | 7757 | Petromyzon marinus | ENSPMAG00000005715 |
9305 | Sarcophilus harrisii | ENSSHAG00000010518 | 9478 | Tarsius syrichta | ENSTSYG00000001532 |
30538 | Vicugna pacos | ENSVPAG00000011840 | 8364 | Xenopus tropicalis | ENSXETG00000030372 |