Basic Information
Gene ID 6926 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name TBX3
Full Name T-box transcription factor TBX3
Organism Homo sapiens [9606]

Cross Reference
UniProt O15119 UniGene Hs.744016
PDB 1H6F OMIM 601621
KEGG hsa:6926 UCSC uc001tvu.1

Protein Interactions
DIP NULL
IntAct O15119
MINT MINT-7970169
STRING 9606.ENSP00000257566

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000257566 Gene3D G3DSA:2.60.40.820 IPR001699 101 309 1.60e-92 Transcription factor, T-box
ENSP00000257566 PANTHER PTHR11267 IPR001699 1 743 0.00e-00 Transcription factor, T-box
ENSP00000257566 Pfam PF00907 IPR001699 104 305 2.10e-79 Transcription factor, T-box
ENSP00000257566 Pfam PF12598 IPR022582 323 410 3.90e-27 Transcription factor, T-box, region of unknown function
ENSP00000257566 PRINTS PR00937 IPR001699 120 144 4.00e-23 Transcription factor, T-box
ENSP00000257566 PRINTS PR00937 IPR001699 276 289 4.00e-23 Transcription factor, T-box
ENSP00000257566 PRINTS PR00937 IPR001699 297 305 4.00e-23 Transcription factor, T-box
ENSP00000257566 ProSitePatterns PS01264 IPR018186 186 204 - Transcription factor, T-box, conserved site
ENSP00000257566 ProSitePatterns PS01283 IPR018186 112 131 - Transcription factor, T-box, conserved site
ENSP00000257566 ProSiteProfiles PS50252 IPR001699 107 305 0.00e-00 Transcription factor, T-box
ENSP00000257566 SMART SM00425 IPR001699 102 310 2.10e-127 Transcription factor, T-box
ENSP00000257566 SUPERFAMILY SSF49417 IPR008967 103 305 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000257566 PF00907 0 T-box T-box
ENSP00000257566 PF12598 9.7e-28 TBX T-box transcription factor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000257566 GO:0006351 biological_process transcription, DNA-templated
ENSP00000257566 GO:0005634 cellular_component nucleus
ENSP00000257566 GO:0003677 molecular_function DNA binding
ENSP00000257566 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9258 Ornithorhynchus anatinus 100078876 7029 Acyrthosiphon pisum 100158703
10224 Saccoglossus kowalevskii 100303520 9823 Sus scrofa 100622658
30195 Bombus terrestris 100642252 8128 Oreochromis niloticus 100698260
132113 Bombus impatiens 100740497 10029 Cricetulus griseus 100751320
143995 Megachile rotundata 100879038 34638 Metaseiulus occidentalis 100906277
9597 Pan paniscus 100985552 9555 Papio anubis 101020127
39432 Saimiri boliviensis 101037725 31033 Takifugu rubripes 101069968
43179 Ictidomys tridecemlineatus 101971131 8083 Xiphophorus maculatus 102231429
7897 Latimeria chalumnae 102364919 6239 Caenorhabditis elegans 175698
10116 Rattus norvegicus 303398 9031 Gallus gallus 374202
7668 Strongylocentrotus purpuratus 592389 7070 Tribolium castaneum 661159
7955 Danio rerio 30253 7227 Drosophila melanogaster 31379
8049 Gadus morhua ENSGMOG00000011728 9978 Ochotona princeps ENSOPRG00000004462
9598 Pan troglodytes 740308 28377 Anolis carolinensis ENSACAG00000000716
9646 Ailuropoda melanoleuca ENSAMEG00000001090 9913 Bos taurus ENSBTAG00000021706
9615 Canis familiaris ENSCAFG00000009216 7719 Ciona intestinalis ENSCING00000008678
9483 Callithrix jacchus ENSCJAG00000001256 10141 Cavia porcellus ENSCPOG00000003952
9361 Dasypus novemcinctus ENSDNOG00000008614 10020 Dipodomys ordii ENSDORG00000000223
9796 Equus caballus ENSECAG00000012861 9365 Erinaceus europaeus ENSEEUG00000008506
9371 Echinops telfairi ENSETEG00000014287 9685 Felis catus ENSFCAG00000024116
69293 Gasterosteus aculeatus ENSGACG00000016783 9595 Gorilla gorilla ENSGGOG00000004238
9785 Loxodonta africana ENSLAFG00000002948 9315 Macropus eugenii ENSMEUG00000013490
9103 Meleagris gallopavo ENSMGAG00000010084 30608 Microcebus murinus ENSMICG00000010947
59463 Myotis lucifugus ENSMLUG00000007567 9544 Macaca mulatta ENSMMUG00000009859
13616 Monodelphis domestica ENSMODG00000012059 9669 Mustela putorius furo ENSMPUG00000002720
61853 Nomascus leucogenys ENSNLEG00000000423 9986 Oryctolagus cuniculus ENSOCUG00000014595
30611 Otolemur garnettii ENSOGAG00000014815 8090 Oryzias latipes ENSORLG00000007316
9813 Procavia capensis ENSPCAG00000009570 9601 Pongo abelii ENSPPYG00000008798
13735 Pelodiscus sinensis ENSPSIG00000006299 132908 Pteropus vampyrus ENSPVAG00000008090
9305 Sarcophilus harrisii ENSSHAG00000004253 37347 Tupaia belangeri ENSTBEG00000014612
59729 Taeniopygia guttata ENSTGUG00000007813 99883 Tetraodon nigroviridis ENSTNIG00000009035
9478 Tarsius syrichta ENSTSYG00000008994 9739 Tursiops truncatus ENSTTRG00000003216
8364 Xenopus tropicalis ENSXETG00000006579