Basic Information | |||
Gene ID | 704678 | ||
Gene Name | HIF1A | ||
Full Name | Hypoxia-inducible factor 1-alpha isoform 2 | ||
Organism | Macaca mulatta [9544] |
Cross Reference | |||
UniProt | F7HKJ4 | UniGene | Mmu.4843 |
PDB | NULL | OMIM | NULL |
KEGG | mcc:704678 | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
XP_001099149 | Pfam | PF00989 | IPR013767 | 94 | 149 | 2.00e-05 | PAS fold |
XP_001099149 | Pfam | PF08778 | IPR014887 | 787 | 826 | 1.50e-22 | HIF-1 alpha, transactivation domain, C-terminal |
XP_001099149 | Pfam | PF11413 | IPR021537 | 550 | 582 | 4.80e-16 | Hypoxia-inducible factor, alpha subunit |
XP_001099149 | PRINTS | PR01080 | IPR001321 | 201 | 224 | 3.10e-48 | Hypoxia-inducible factor-1 alpha |
XP_001099149 | PRINTS | PR01080 | IPR001321 | 360 | 378 | 3.10e-48 | Hypoxia-inducible factor-1 alpha |
XP_001099149 | PRINTS | PR01080 | IPR001321 | 417 | 435 | 3.10e-48 | Hypoxia-inducible factor-1 alpha |
XP_001099149 | PRINTS | PR01080 | IPR001321 | 457 | 477 | 3.10e-48 | Hypoxia-inducible factor-1 alpha |
XP_001099149 | ProSiteProfiles | PS50112 | IPR000014 | 247 | 298 | 0.00e-00 | PAS domain |
XP_001099149 | ProSiteProfiles | PS50112 | IPR000014 | 93 | 148 | 0.00e-00 | PAS domain |
XP_001099149 | ProSiteProfiles | PS50888 | IPR011598 | 17 | 70 | 0.00e-00 | Myc-type, basic helix-loop-helix (bHLH) domain |
XP_001099149 | SMART | SM00086 | IPR001610 | 302 | 345 | 2.60e-11 | PAC motif |
XP_001099149 | SMART | SM00091 | IPR000014 | 230 | 296 | 8.20e-11 | PAS domain |
XP_001099149 | SMART | SM00091 | IPR000014 | 87 | 153 | 1.50e-12 | PAS domain |
XP_001099149 | SMART | SM00353 | IPR011598 | 23 | 78 | 2.80e-11 | Myc-type, basic helix-loop-helix (bHLH) domain |
XP_001099149 | SUPERFAMILY | SSF47459 | IPR011598 | 15 | 71 | 0.00e-00 | Myc-type, basic helix-loop-helix (bHLH) domain |
XP_001099149 | SUPERFAMILY | SSF55785 | IPR000014 | 242 | 343 | 0.00e-00 | PAS domain |
XP_001099149 | SUPERFAMILY | SSF55785 | IPR000014 | 96 | 207 | 0.00e-00 | PAS domain |
XP_001099149 | TIGRFAM | TIGR00229 | IPR000014 | 100 | 153 | 5.10e-06 | PAS domain |
XP_001099149 | TIGRFAM | TIGR00229 | IPR000014 | 249 | 330 | 2.20e-08 | PAS domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
XP_001099149 | PF14598 | 2.6e-26 | PAS_11 | PAS domain |
XP_001099149 | PF08447 | 9.1e-26 | PAS_3 | PAS fold |
XP_001099149 | PF08778 | 7.7e-23 | HIF-1a_CTAD | HIF-1 alpha C terminal transactivation domain |
XP_001099149 | PF11413 | 2e-16 | HIF-1 | Hypoxia-inducible factor-1 |
XP_001099149 | PF00989 | 1.1e-15 | PAS | PAS fold |
XP_001099149 | PF13426 | 1.7e-12 | PAS_9 | PAS domain |
XP_001099149 | PF08448 | 1.6e-07 | PAS_4 | PAS fold |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
XP_001099149 | GO:0001666 | biological_process | response to hypoxia |
XP_001099149 | GO:0006351 | biological_process | transcription, DNA-templated |
XP_001099149 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
XP_001099149 | GO:0007165 | biological_process | signal transduction |
XP_001099149 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
XP_001099149 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
XP_001099149 | GO:0071456 | biological_process | cellular response to hypoxia |
XP_001099149 | GO:0005634 | cellular_component | nucleus |
XP_001099149 | GO:0005737 | cellular_component | cytoplasm |
XP_001099149 | GO:0003677 | molecular_function | DNA binding |
XP_001099149 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
XP_001099149 | GO:0004871 | molecular_function | signal transducer activity |
XP_001099149 | GO:0035035 | molecular_function | histone acetyltransferase binding |
XP_001099149 | GO:0046983 | molecular_function | protein dimerization activity |