Basic Information
Gene ID 745437
Gene Name EZH2
Full Name Enhancer of zeste homolog 2
Organism Pan troglodytes [9598]

Cross Reference
UniProt H2QVK6 UniGene NULL
PDB NULL OMIM NULL
KEGG ptr:745437 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPTRP00000033970 Pfam PF00856 IPR001214 623 726 1.30e-22 SET domain
ENSPTRP00000033970 Pfam PF11616 IPR021654 39 68 6.80e-19 WD repeat binding protein EZH2
ENSPTRP00000033970 ProSiteProfiles PS50280 IPR001214 612 727 0.00e-00 SET domain
ENSPTRP00000033970 ProSiteProfiles PS51633 IPR026489 503 605 0.00e-00 CXC domain
ENSPTRP00000033970 SMART SM00317 IPR001214 612 733 2.10e-40 SET domain
ENSPTRP00000033970 SMART SM00717 IPR001005 159 250 1.70e-05 SANT/Myb domain
ENSPTRP00000033970 SMART SM00717 IPR001005 428 476 3.30e-03 SANT/Myb domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPTRP00000033970 PF00856 1.3e-22 SET SET domain
ENSPTRP00000033970 PF11616 3e-19 EZH2_WD-Binding WD repeat binding protein EZH2

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPTRP00000033970 GO:0006351 biological_process transcription, DNA-templated
ENSPTRP00000033970 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSPTRP00000033970 GO:0005634 cellular_component nucleus
ENSPTRP00000033970 GO:0035098 cellular_component ESC/E(Z) complex
ENSPTRP00000033970 GO:0003682 molecular_function chromatin binding
ENSPTRP00000033970 GO:0018024 molecular_function histone-lysine N-methyltransferase activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100168406 9986 Oryctolagus cuniculus 100345157
9823 Sus scrofa 100625497 30195 Bombus terrestris 100647736
132113 Bombus impatiens 100747000 10029 Cricetulus griseus 100758055
9597 Pan paniscus 100971244 9555 Papio anubis 101001043
39432 Saimiri boliviensis 101051611 43179 Ictidomys tridecemlineatus 101968825
9031 Gallus gallus 420784 9615 Canis familiaris 475511
143995 Megachile rotundata 100883902 9483 Callithrix jacchus ENSCJAG00000016360
10141 Cavia porcellus ENSCPOG00000003710 30608 Microcebus murinus ENSMICG00000011127
9978 Ochotona princeps ENSOPRG00000007788 99883 Tetraodon nigroviridis ENSTNIG00000001024
28377 Anolis carolinensis ENSACAG00000013910 9358 Choloepus hoffmanni ENSCHOG00000013009
51511 Ciona savignyi ENSCSAVG00000002002 9361 Dasypus novemcinctus ENSDNOG00000013912
10020 Dipodomys ordii ENSDORG00000007731 9685 Felis catus ENSFCAG00000008618
9595 Gorilla gorilla ENSGGOG00000014846 8049 Gadus morhua ENSGMOG00000015628
9785 Loxodonta africana ENSLAFG00000001578 59463 Myotis lucifugus ENSMLUG00000002498
9544 Macaca mulatta ENSMMUG00000013494 13616 Monodelphis domestica ENSMODG00000001852
9669 Mustela putorius furo ENSMPUG00000007249 61853 Nomascus leucogenys ENSNLEG00000003596
9258 Ornithorhynchus anatinus ENSOANG00000000279 30611 Otolemur garnettii ENSOGAG00000010387
9601 Pongo abelii ENSPPYG00000018147 13735 Pelodiscus sinensis ENSPSIG00000014933
9305 Sarcophilus harrisii ENSSHAG00000017743 37347 Tupaia belangeri ENSTBEG00000015636
59729 Taeniopygia guttata ENSTGUG00000001770 31033 Takifugu rubripes ENSTRUG00000015011
9478 Tarsius syrichta ENSTSYG00000000831 30538 Vicugna pacos ENSVPAG00000001437
8364 Xenopus tropicalis ENSXETG00000020146