Basic Information
Gene ID ENSCING00000014406
Gene Name ap4
Full Name Uncharacterized protein
Organism Ciona intestinalis [7719]

Cross Reference
UniProt F6ZWX3 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSCINP00000026074 Gene3D G3DSA:4.10.280.10 IPR011598 98 167 4.40e-16 Myc-type, basic helix-loop-helix (bHLH) domain
ENSCINP00000026074 Pfam PF00010 IPR011598 98 149 3.70e-16 Myc-type, basic helix-loop-helix (bHLH) domain
ENSCINP00000026074 ProSiteProfiles PS50888 IPR011598 97 148 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSCINP00000026074 SMART SM00353 IPR011598 103 154 8.30e-17 Myc-type, basic helix-loop-helix (bHLH) domain
ENSCINP00000026074 SUPERFAMILY SSF47459 IPR011598 95 174 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSCINP00000026074 PF00010 8.2e-17 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSCINP00000026074 GO:0006366 biological_process transcription from RNA polymerase II promoter
ENSCINP00000026074 GO:0006461 biological_process protein complex assembly
ENSCINP00000026074 GO:0006978 biological_process DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
ENSCINP00000026074 GO:0008285 biological_process negative regulation of cell proliferation
ENSCINP00000026074 GO:0043065 biological_process positive regulation of apoptotic process
ENSCINP00000026074 GO:0043066 biological_process negative regulation of apoptotic process
ENSCINP00000026074 GO:0043392 biological_process negative regulation of DNA binding
ENSCINP00000026074 GO:0043922 biological_process negative regulation by host of viral transcription
ENSCINP00000026074 GO:0043923 biological_process positive regulation by host of viral transcription
ENSCINP00000026074 GO:0045736 biological_process negative regulation of cyclin-dependent protein serine/threonine kinase activity
ENSCINP00000026074 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ENSCINP00000026074 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSCINP00000026074 GO:0071157 biological_process negative regulation of cell cycle arrest
ENSCINP00000026074 GO:0071549 biological_process cellular response to dexamethasone stimulus
ENSCINP00000026074 GO:2001269 biological_process positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
ENSCINP00000026074 GO:0005634 cellular_component nucleus
ENSCINP00000026074 GO:0017053 cellular_component transcriptional repressor complex
ENSCINP00000026074 GO:0000978 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding
ENSCINP00000026074 GO:0001077 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
ENSCINP00000026074 GO:0003677 molecular_function DNA binding
ENSCINP00000026074 GO:0003705 molecular_function RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
ENSCINP00000026074 GO:0003713 molecular_function transcription coactivator activity
ENSCINP00000026074 GO:0005515 molecular_function protein binding
ENSCINP00000026074 GO:0042803 molecular_function protein homodimerization activity
ENSCINP00000026074 GO:0042826 molecular_function histone deacetylase binding
ENSCINP00000026074 GO:0043565 molecular_function sequence-specific DNA binding
ENSCINP00000026074 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSCINP00000026074 GO:0046982 molecular_function protein heterodimerization activity
ENSCINP00000026074 GO:0070888 molecular_function E-box binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100069711 10224 Saccoglossus kowalevskii 100375636
28377 Anolis carolinensis 100556024 400682 Amphimedon queenslandica 100635737
10141 Cavia porcellus 100718065 34638 Metaseiulus occidentalis 100902969
30611 Otolemur garnettii 100944090 9555 Papio anubis 101005019
9685 Felis catus 101095461 9595 Gorilla gorilla 101146500
8083 Xiphophorus maculatus 102231357 59463 Myotis lucifugus 102420659
7227 Drosophila melanogaster 34956 7668 Strongylocentrotus purpuratus 578637
7029 Acyrthosiphon pisum 100161809 9483 Callithrix jacchus 100391868
9646 Ailuropoda melanoleuca 100474477 30195 Bombus terrestris 100644452
9785 Loxodonta africana 100663165 7425 Nasonia vitripennis 100679356
132113 Bombus impatiens 100748243 10029 Cricetulus griseus 100751080
143995 Megachile rotundata 100883438 9305 Sarcophilus harrisii 100925765
9597 Pan paniscus 100983876 39432 Saimiri boliviensis 101043319
8090 Oryzias latipes 101175405 43179 Ictidomys tridecemlineatus 101973956
10116 Rattus norvegicus 360482 7070 Tribolium castaneum 656093
7460 Apis mellifera 726729 51511 Ciona savignyi ENSCSAVG00000000333
10020 Dipodomys ordii ENSDORG00000004656 8049 Gadus morhua ENSGMOG00000014930
7897 Latimeria chalumnae ENSLACG00000000328 9598 Pan troglodytes ENSPTRG00000007713
59729 Taeniopygia guttata ENSTGUG00000003940 9739 Tursiops truncatus ENSTTRG00000002710
30538 Vicugna pacos ENSVPAG00000008001 9365 Erinaceus europaeus ENSEEUG00000006004
9371 Echinops telfairi ENSETEG00000008634 69293 Gasterosteus aculeatus ENSGACG00000011329
9031 Gallus gallus ENSGALG00000027823 9315 Macropus eugenii ENSMEUG00000000888
9103 Meleagris gallopavo ENSMGAG00000009411 9669 Mustela putorius furo ENSMPUG00000015023
9258 Ornithorhynchus anatinus ENSOANG00000019858 9986 Oryctolagus cuniculus ENSOCUG00000024550
9978 Ochotona princeps ENSOPRG00000001061 9813 Procavia capensis ENSPCAG00000011134
9601 Pongo abelii ENSPPYG00000007054 13735 Pelodiscus sinensis ENSPSIG00000009002
132908 Pteropus vampyrus ENSPVAG00000005418 37347 Tupaia belangeri ENSTBEG00000014089
99883 Tetraodon nigroviridis ENSTNIG00000009740 31033 Takifugu rubripes ENSTRUG00000006111