Basic Information
Gene ID ENSDARG00000055588
Gene Name stat5.2
Full Name Signal transducer and activator of transcription
Organism Danio rerio [7955]

Cross Reference
UniProt A4QNT9 UniGene Dr.140952
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSDARP00000110501 Gene3D G3DSA:1.10.238.10 IPR011992 473 598 1.50e-47 EF-hand domain pair
ENSDARP00000110501 Gene3D G3DSA:1.10.532.10 IPR013799 1 125 6.40e-46 STAT transcription factor, protein interaction
ENSDARP00000110501 Gene3D G3DSA:1.20.1050.20 IPR013800 140 332 3.20e-60 STAT transcription factor, all-alpha
ENSDARP00000110501 Gene3D G3DSA:2.60.40.630 IPR012345 333 472 4.00e-64 STAT transcription factor, DNA-binding, subdomain
ENSDARP00000110501 Gene3D G3DSA:3.30.505.10 IPR000980 600 710 8.00e-42 SH2 domain
ENSDARP00000110501 PANTHER PTHR11801 IPR001217 2 780 0.00e-00 Transcription factor STAT
ENSDARP00000110501 Pfam PF00017 IPR000980 596 661 5.20e-10 SH2 domain
ENSDARP00000110501 Pfam PF01017 IPR013800 139 330 3.10e-57 STAT transcription factor, all-alpha
ENSDARP00000110501 Pfam PF02864 IPR013801 332 584 5.20e-92 STAT transcription factor, DNA-binding
ENSDARP00000110501 Pfam PF02865 IPR013799 2 125 3.50e-46 STAT transcription factor, protein interaction
ENSDARP00000110501 ProSiteProfiles PS50001 IPR000980 590 691 0.00e-00 SH2 domain
ENSDARP00000110501 SMART SM00252 IPR000980 588 681 4.40e-08 SH2 domain
ENSDARP00000110501 SMART SM00964 IPR013799 2 126 2.50e-58 STAT transcription factor, protein interaction
ENSDARP00000110501 SUPERFAMILY SSF47655 IPR015988 138 332 0.00e-00 STAT transcription factor, coiled coil
ENSDARP00000110501 SUPERFAMILY SSF48092 IPR013799 1 125 0.00e-00 STAT transcription factor, protein interaction
ENSDARP00000110501 SUPERFAMILY SSF49417 IPR008967 326 585 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSDARP00000110501 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSDARP00000110501 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSDARP00000110501 PF02865 0 STAT_int STAT protein, protein interaction domain
ENSDARP00000110501 PF00017 8e-11 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSDARP00000110501 GO:0001553 biological_process luteinization
ENSDARP00000110501 GO:0001779 biological_process natural killer cell differentiation
ENSDARP00000110501 GO:0006351 biological_process transcription, DNA-templated
ENSDARP00000110501 GO:0007259 biological_process JAK-STAT cascade
ENSDARP00000110501 GO:0007565 biological_process female pregnancy
ENSDARP00000110501 GO:0007595 biological_process lactation
ENSDARP00000110501 GO:0019218 biological_process regulation of steroid metabolic process
ENSDARP00000110501 GO:0019915 biological_process lipid storage
ENSDARP00000110501 GO:0030155 biological_process regulation of cell adhesion
ENSDARP00000110501 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSDARP00000110501 GO:0038161 biological_process prolactin signaling pathway
ENSDARP00000110501 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSDARP00000110501 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSDARP00000110501 GO:0043029 biological_process T cell homeostasis
ENSDARP00000110501 GO:0043066 biological_process negative regulation of apoptotic process
ENSDARP00000110501 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSDARP00000110501 GO:0045579 biological_process positive regulation of B cell differentiation
ENSDARP00000110501 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSDARP00000110501 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSDARP00000110501 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSDARP00000110501 GO:0046543 biological_process development of secondary female sexual characteristics
ENSDARP00000110501 GO:0050729 biological_process positive regulation of inflammatory response
ENSDARP00000110501 GO:0005634 cellular_component nucleus
ENSDARP00000110501 GO:0005737 cellular_component cytoplasm
ENSDARP00000110501 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSDARP00000110501 GO:0004871 molecular_function signal transducer activity
ENSDARP00000110501 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
28377 Anolis carolinensis ENSACAG00000009680 34638 Metaseiulus occidentalis 100907258

Paralogs
ENSDARG00000019392