Basic Information
Gene ID ENSETEG00000016614
Gene Name ar
Full Name Androgen receptor
Organism Echinops telfairi [9371]

Cross Reference
UniProt Q2MDI0 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSETEP00000013478 Gene3D G3DSA:1.10.565.10 IPR008946 599 641 2.40e-10 Nuclear hormone receptor, ligand-binding
ENSETEP00000013478 Gene3D G3DSA:1.10.565.10 IPR008946 706 849 1.00e-51 Nuclear hormone receptor, ligand-binding
ENSETEP00000013478 Gene3D G3DSA:3.30.50.10 IPR013088 538 598 1.00e-25 Zinc finger, NHR/GATA-type
ENSETEP00000013478 Pfam PF00104 IPR000536 707 849 2.20e-20 Nuclear hormone receptor, ligand-binding, core
ENSETEP00000013478 Pfam PF00105 IPR001628 540 608 6.80e-27 Zinc finger, nuclear hormone receptor-type
ENSETEP00000013478 Pfam PF02166 IPR001103 6 443 1.50e-229 Androgen receptor
ENSETEP00000013478 PRINTS PR00047 IPR001628 542 558 1.90e-13 Zinc finger, nuclear hormone receptor-type
ENSETEP00000013478 PRINTS PR00047 IPR001628 558 573 1.90e-13 Zinc finger, nuclear hormone receptor-type
ENSETEP00000013478 PRINTS PR00047 IPR001628 591 599 1.90e-13 Zinc finger, nuclear hormone receptor-type
ENSETEP00000013478 PRINTS PR00047 IPR001628 599 607 1.90e-13 Zinc finger, nuclear hormone receptor-type
ENSETEP00000013478 PRINTS PR00521 IPR001103 164 183 2.70e-103 Androgen receptor
ENSETEP00000013478 PRINTS PR00521 IPR001103 212 232 2.70e-103 Androgen receptor
ENSETEP00000013478 PRINTS PR00521 IPR001103 258 278 2.70e-103 Androgen receptor
ENSETEP00000013478 PRINTS PR00521 IPR001103 27 45 2.70e-103 Androgen receptor
ENSETEP00000013478 PRINTS PR00521 IPR001103 295 315 2.70e-103 Androgen receptor
ENSETEP00000013478 PRINTS PR00521 IPR001103 340 362 2.70e-103 Androgen receptor
ENSETEP00000013478 PRINTS PR00521 IPR001103 376 395 2.70e-103 Androgen receptor
ENSETEP00000013478 PRINTS PR00521 IPR001103 426 443 2.70e-103 Androgen receptor
ENSETEP00000013478 PRINTS PR00521 IPR001103 6 25 2.70e-103 Androgen receptor
ENSETEP00000013478 ProSitePatterns PS00031 IPR001628 542 568 - Zinc finger, nuclear hormone receptor-type
ENSETEP00000013478 ProSiteProfiles PS51030 IPR001628 539 614 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSETEP00000013478 SMART SM00399 IPR001628 539 610 1.10e-34 Zinc finger, nuclear hormone receptor-type
ENSETEP00000013478 SMART SM00430 IPR000536 692 849 4.50e-16 Nuclear hormone receptor, ligand-binding, core
ENSETEP00000013478 SUPERFAMILY SSF48508 IPR008946 706 849 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSETEP00000013478 PF02166 0 Androgen_recep Androgen receptor
ENSETEP00000013478 PF00105 2.9e-27 zf-C4 Zinc finger, C4 type (two domains)
ENSETEP00000013478 PF00104 2.2e-20 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSETEP00000013478 GO:0006351 biological_process transcription, DNA-templated
ENSETEP00000013478 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSETEP00000013478 GO:0008284 biological_process positive regulation of cell proliferation
ENSETEP00000013478 GO:0030521 biological_process androgen receptor signaling pathway
ENSETEP00000013478 GO:0030522 biological_process intracellular receptor signaling pathway
ENSETEP00000013478 GO:0042327 biological_process positive regulation of phosphorylation
ENSETEP00000013478 GO:0043401 biological_process steroid hormone mediated signaling pathway
ENSETEP00000013478 GO:0045720 biological_process negative regulation of integrin biosynthetic process
ENSETEP00000013478 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSETEP00000013478 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSETEP00000013478 GO:0051092 biological_process positive regulation of NF-kappaB transcription factor activity
ENSETEP00000013478 GO:0090003 biological_process regulation of establishment of protein localization to plasma membrane
ENSETEP00000013478 GO:2001237 biological_process negative regulation of extrinsic apoptotic signaling pathway
ENSETEP00000013478 GO:0000790 cellular_component nuclear chromatin
ENSETEP00000013478 GO:0005634 cellular_component nucleus
ENSETEP00000013478 GO:0005737 cellular_component cytoplasm
ENSETEP00000013478 GO:0003677 molecular_function DNA binding
ENSETEP00000013478 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSETEP00000013478 GO:0003707 molecular_function steroid hormone receptor activity
ENSETEP00000013478 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSETEP00000013478 GO:0004882 molecular_function androgen receptor activity
ENSETEP00000013478 GO:0005496 molecular_function steroid binding
ENSETEP00000013478 GO:0008013 molecular_function beta-catenin binding
ENSETEP00000013478 GO:0008270 molecular_function zinc ion binding
ENSETEP00000013478 GO:0008289 molecular_function lipid binding
ENSETEP00000013478 GO:0043565 molecular_function sequence-specific DNA binding
ENSETEP00000013478 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSETEP00000013478 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7955 Danio rerio 100005148 9986 Oryctolagus cuniculus 100009193
9646 Ailuropoda melanoleuca 100464952 30611 Otolemur garnettii 100960541
9597 Pan paniscus 100976456 39432 Saimiri boliviensis 101040429
9685 Felis catus 101081787 9595 Gorilla gorilla 101143264
8083 Xiphophorus maculatus 102229873 59463 Myotis lucifugus 102427580
9913 Bos taurus 280675 28377 Anolis carolinensis ENSACAG00000009496
9615 Canis familiaris ENSCAFG00000016656 9358 Choloepus hoffmanni ENSCHOG00000004326
9796 Equus caballus ENSECAG00000010160 9365 Erinaceus europaeus ENSEEUG00000010162
10029 Cricetulus griseus 100752675 9555 Papio anubis 101020931
9669 Mustela putorius furo 101681169 43179 Ictidomys tridecemlineatus 101970574
10090 Mus musculus 11835 10116 Rattus norvegicus 24208
9483 Callithrix jacchus ENSCJAG00000003563 10141 Cavia porcellus ENSCPOG00000007636
10020 Dipodomys ordii ENSDORG00000010157 69293 Gasterosteus aculeatus ENSGACG00000020332
9031 Gallus gallus ENSGALG00000004596 9315 Macropus eugenii ENSMEUG00000016129
9544 Macaca mulatta ENSMMUG00000011437 61853 Nomascus leucogenys ENSNLEG00000000573
8128 Oreochromis niloticus ENSONIG00000012854 13735 Pelodiscus sinensis ENSPSIG00000010176
59729 Taeniopygia guttata ENSTGUG00000002760 9478 Tarsius syrichta ENSTSYG00000009965
9739 Tursiops truncatus ENSTTRG00000004230 8364 Xenopus tropicalis ENSXETG00000005089
8049 Gadus morhua ENSGMOG00000010216 7897 Latimeria chalumnae ENSLACG00000015024
9103 Meleagris gallopavo ENSMGAG00000010900 30608 Microcebus murinus ENSMICG00000014721
13616 Monodelphis domestica ENSMODG00000012412 8090 Oryzias latipes ENSORLG00000009520
9813 Procavia capensis ENSPCAG00000015018 132908 Pteropus vampyrus ENSPVAG00000001117
42254 Sorex araneus ENSSARG00000005970 9305 Sarcophilus harrisii ENSSHAG00000016645
9823 Sus scrofa ENSSSCG00000012371 37347 Tupaia belangeri ENSTBEG00000015310