Basic Information
Gene ID ENSMODG00000018647
Gene Name HES4
Full Name Uncharacterized protein
Organism Monodelphis domestica [13616]

Cross Reference
UniProt H9H763 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMODP00000023250 Gene3D G3DSA:4.10.280.10 IPR011598 33 93 1.80e-14 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMODP00000023250 Pfam PF00010 IPR011598 35 92 1.50e-14 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMODP00000023250 Pfam PF07527 IPR003650 109 150 5.40e-20 Orange
ENSMODP00000023250 ProSiteProfiles PS50888 IPR011598 34 91 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMODP00000023250 ProSiteProfiles PS51054 IPR003650 110 143 0.00e-00 Orange
ENSMODP00000023250 SMART SM00353 IPR011598 40 97 1.50e-16 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMODP00000023250 SMART SM00511 IPR018352 108 152 1.50e-20 Orange subgroup
ENSMODP00000023250 SUPERFAMILY SSF47459 IPR011598 25 94 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMODP00000023250 PF07527 3e-20 Hairy_orange Hairy Orange
ENSMODP00000023250 PF00010 5.8e-15 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMODP00000023250 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSMODP00000023250 GO:0006351 biological_process transcription, DNA-templated
ENSMODP00000023250 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMODP00000023250 GO:0007219 biological_process Notch signaling pathway
ENSMODP00000023250 GO:0007275 biological_process multicellular organismal development
ENSMODP00000023250 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ENSMODP00000023250 GO:0005634 cellular_component nucleus
ENSMODP00000023250 GO:0003677 molecular_function DNA binding
ENSMODP00000023250 GO:0043565 molecular_function sequence-specific DNA binding
ENSMODP00000023250 GO:0046982 molecular_function protein heterodimerization activity
ENSMODP00000023250 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8364 Xenopus tropicalis 100038090 7029 Acyrthosiphon pisum 100163408
28377 Anolis carolinensis 100558625 30195 Bombus terrestris 100643950
8128 Oreochromis niloticus 100700093 132113 Bombus impatiens 100741422
31033 Takifugu rubripes 101070803 7897 Latimeria chalumnae 102354272
13735 Pelodiscus sinensis 102463824 7227 Drosophila melanogaster 35800
9031 Gallus gallus 395128 7719 Ciona intestinalis ENSCING00000003929
9361 Dasypus novemcinctus ENSDNOG00000024495 9371 Echinops telfairi ENSETEG00000019989
69293 Gasterosteus aculeatus ENSGACG00000007334 8049 Gadus morhua ENSGMOG00000000092
9315 Macropus eugenii ENSMEUG00000013941 9103 Meleagris gallopavo ENSMGAG00000007566
8090 Oryzias latipes ENSORLG00000005453 99883 Tetraodon nigroviridis ENSTNIG00000015161
8083 Xiphophorus maculatus ENSXMAG00000003794