Basic Information | |||
Gene ID | ENSPPYG00000004680 | ||
Gene Name | STAT6 | ||
Full Name | Signal transducer and activator of transcription | ||
Organism | Pongo abelii [9601] |
Cross Reference | |||
UniProt | H2NHS4 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSPPYP00000005333 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 416 | 541 | 2.40e-41 | EF-hand domain pair |
ENSPPYP00000005333 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 1 | 114 | 6.10e-23 | STAT transcription factor, protein interaction |
ENSPPYP00000005333 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 115 | 273 | 4.80e-22 | STAT transcription factor, all-alpha |
ENSPPYP00000005333 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 275 | 415 | 3.10e-43 | STAT transcription factor, DNA-binding, subdomain |
ENSPPYP00000005333 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 542 | 650 | 6.70e-37 | SH2 domain |
ENSPPYP00000005333 | PANTHER | PTHR11801 | IPR001217 | 2 | 718 | 0.00e-00 | Transcription factor STAT |
ENSPPYP00000005333 | Pfam | PF00017 | IPR000980 | 538 | 616 | 3.70e-10 | SH2 domain |
ENSPPYP00000005333 | Pfam | PF01017 | IPR013800 | 178 | 271 | 2.40e-21 | STAT transcription factor, all-alpha |
ENSPPYP00000005333 | Pfam | PF02864 | IPR013801 | 273 | 527 | 6.40e-94 | STAT transcription factor, DNA-binding |
ENSPPYP00000005333 | Pfam | PF02865 | IPR013799 | 2 | 115 | 3.30e-24 | STAT transcription factor, protein interaction |
ENSPPYP00000005333 | Pfam | PF14596 | IPR028187 | 655 | 847 | 1.40e-114 | STAT6, C-terminal |
ENSPPYP00000005333 | ProSiteProfiles | PS50001 | IPR000980 | 517 | 632 | 0.00e-00 | SH2 domain |
ENSPPYP00000005333 | SMART | SM00252 | IPR000980 | 540 | 622 | 1.60e-07 | SH2 domain |
ENSPPYP00000005333 | SMART | SM00964 | IPR013799 | 2 | 116 | 1.80e-40 | STAT transcription factor, protein interaction |
ENSPPYP00000005333 | SUPERFAMILY | SSF47655 | IPR015988 | 112 | 273 | 0.00e-00 | STAT transcription factor, coiled coil |
ENSPPYP00000005333 | SUPERFAMILY | SSF48092 | IPR013799 | 1 | 115 | 0.00e-00 | STAT transcription factor, protein interaction |
ENSPPYP00000005333 | SUPERFAMILY | SSF49417 | IPR008967 | 265 | 528 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSPPYP00000005333 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
ENSPPYP00000005333 | PF14596 | 0 | STAT6_C | STAT6 C-terminal |
ENSPPYP00000005333 | PF01017 | 4.7e-25 | STAT_alpha | STAT protein, all-alpha domain |
ENSPPYP00000005333 | PF02865 | 8.6e-25 | STAT_int | STAT protein, protein interaction domain |
ENSPPYP00000005333 | PF00017 | 1.8e-10 | SH2 | SH2 domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSPPYP00000005333 | GO:0001553 | biological_process | luteinization |
ENSPPYP00000005333 | GO:0001779 | biological_process | natural killer cell differentiation |
ENSPPYP00000005333 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSPPYP00000005333 | GO:0007259 | biological_process | JAK-STAT cascade |
ENSPPYP00000005333 | GO:0007565 | biological_process | female pregnancy |
ENSPPYP00000005333 | GO:0007595 | biological_process | lactation |
ENSPPYP00000005333 | GO:0019218 | biological_process | regulation of steroid metabolic process |
ENSPPYP00000005333 | GO:0019915 | biological_process | lipid storage |
ENSPPYP00000005333 | GO:0030155 | biological_process | regulation of cell adhesion |
ENSPPYP00000005333 | GO:0030856 | biological_process | regulation of epithelial cell differentiation |
ENSPPYP00000005333 | GO:0038161 | biological_process | prolactin signaling pathway |
ENSPPYP00000005333 | GO:0040018 | biological_process | positive regulation of multicellular organism growth |
ENSPPYP00000005333 | GO:0042104 | biological_process | positive regulation of activated T cell proliferation |
ENSPPYP00000005333 | GO:0043029 | biological_process | T cell homeostasis |
ENSPPYP00000005333 | GO:0045086 | biological_process | positive regulation of interleukin-2 biosynthetic process |
ENSPPYP00000005333 | GO:0045579 | biological_process | positive regulation of B cell differentiation |
ENSPPYP00000005333 | GO:0045647 | biological_process | negative regulation of erythrocyte differentiation |
ENSPPYP00000005333 | GO:0045931 | biological_process | positive regulation of mitotic cell cycle |
ENSPPYP00000005333 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
ENSPPYP00000005333 | GO:0046543 | biological_process | development of secondary female sexual characteristics |
ENSPPYP00000005333 | GO:0050729 | biological_process | positive regulation of inflammatory response |
ENSPPYP00000005333 | GO:0005634 | cellular_component | nucleus |
ENSPPYP00000005333 | GO:0005737 | cellular_component | cytoplasm |
ENSPPYP00000005333 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSPPYP00000005333 | GO:0004871 | molecular_function | signal transducer activity |
ENSPPYP00000005333 | GO:0005509 | molecular_function | calcium ion binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9483 | Callithrix jacchus | ENSCJAG00000010327 | 10020 | Dipodomys ordii | ENSDORG00000012548 |
9785 | Loxodonta africana | ENSLAFG00000005970 | 30608 | Microcebus murinus | ENSMICG00000009087 |
9796 | Equus caballus | 100050053 | 9823 | Sus scrofa | 100627682 |
10029 | Cricetulus griseus | 100753838 | 30611 | Otolemur garnettii | 100949888 |
9597 | Pan paniscus | 100989067 | 9555 | Papio anubis | 101023204 |
39432 | Saimiri boliviensis | 101029869 | 31033 | Takifugu rubripes | 101065277 |
9685 | Felis catus | 101089873 | 9595 | Gorilla gorilla | 101130575 |
9669 | Mustela putorius furo | 101676980 | 43179 | Ictidomys tridecemlineatus | 101967693 |
9544 | Macaca mulatta | 714159 | 28377 | Anolis carolinensis | ENSACAG00000009680 |
9365 | Erinaceus europaeus | ENSEEUG00000005856 | 9371 | Echinops telfairi | ENSETEG00000014957 |
9315 | Macropus eugenii | ENSMEUG00000016670 | 59463 | Myotis lucifugus | ENSMLUG00000006689 |
13616 | Monodelphis domestica | ENSMODG00000019411 | 61853 | Nomascus leucogenys | ENSNLEG00000017396 |
9978 | Ochotona princeps | ENSOPRG00000013409 | 9813 | Procavia capensis | ENSPCAG00000009432 |
132908 | Pteropus vampyrus | ENSPVAG00000003949 | 42254 | Sorex araneus | ENSSARG00000001630 |
37347 | Tupaia belangeri | ENSTBEG00000013664 | 59729 | Taeniopygia guttata | ENSTGUG00000015716 |
99883 | Tetraodon nigroviridis | ENSTNIG00000015103 | 9478 | Tarsius syrichta | ENSTSYG00000000267 |
9739 | Tursiops truncatus | ENSTTRG00000013064 | 8364 | Xenopus tropicalis | ENSXETG00000004431 |
8083 | Xiphophorus maculatus | ENSXMAG00000010611 | 9598 | Pan troglodytes | ENSPTRG00000005121 |