Basic Information
Gene ID ENSPTRG00000017548
Gene Name MSX2
Full Name Homeobox protein MSX-2
Organism Pan troglodytes [9598]

Cross Reference
UniProt H2QS17 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPTRP00000029971 Gene3D G3DSA:1.10.10.60 IPR009057 118 201 5.00e-27 Homeodomain-like
ENSPTRP00000029971 Pfam PF00046 IPR001356 143 199 5.30e-22 Homeobox domain
ENSPTRP00000029971 PRINTS PR00024 IPR020479 164 175 1.10e-06 Homeodomain, metazoa
ENSPTRP00000029971 PRINTS PR00024 IPR020479 179 189 1.10e-06 Homeodomain, metazoa
ENSPTRP00000029971 PRINTS PR00024 IPR020479 189 198 1.10e-06 Homeodomain, metazoa
ENSPTRP00000029971 ProSitePatterns PS00027 IPR017970 175 198 - Homeobox, conserved site
ENSPTRP00000029971 ProSiteProfiles PS50071 IPR001356 140 200 0.00e-00 Homeobox domain
ENSPTRP00000029971 SMART SM00389 IPR001356 142 204 1.20e-27 Homeobox domain
ENSPTRP00000029971 SUPERFAMILY SSF46689 IPR009057 121 201 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPTRP00000029971 PF00046 3.4e-22 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPTRP00000029971 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSPTRP00000029971 GO:0001649 biological_process osteoblast differentiation
ENSPTRP00000029971 GO:0002063 biological_process chondrocyte development
ENSPTRP00000029971 GO:0002076 biological_process osteoblast development
ENSPTRP00000029971 GO:0003148 biological_process outflow tract septum morphogenesis
ENSPTRP00000029971 GO:0003198 biological_process epithelial to mesenchymal transition involved in endocardial cushion formation
ENSPTRP00000029971 GO:0003416 biological_process endochondral bone growth
ENSPTRP00000029971 GO:0006351 biological_process transcription, DNA-templated
ENSPTRP00000029971 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSPTRP00000029971 GO:0007275 biological_process multicellular organismal development
ENSPTRP00000029971 GO:0008285 biological_process negative regulation of cell proliferation
ENSPTRP00000029971 GO:0009952 biological_process anterior/posterior pattern specification
ENSPTRP00000029971 GO:0023019 biological_process signal transduction involved in regulation of gene expression
ENSPTRP00000029971 GO:0030513 biological_process positive regulation of BMP signaling pathway
ENSPTRP00000029971 GO:0032792 biological_process negative regulation of CREB transcription factor activity
ENSPTRP00000029971 GO:0035115 biological_process embryonic forelimb morphogenesis
ENSPTRP00000029971 GO:0035116 biological_process embryonic hindlimb morphogenesis
ENSPTRP00000029971 GO:0035313 biological_process wound healing, spreading of epidermal cells
ENSPTRP00000029971 GO:0035880 biological_process embryonic nail plate morphogenesis
ENSPTRP00000029971 GO:0042640 biological_process anagen
ENSPTRP00000029971 GO:0043066 biological_process negative regulation of apoptotic process
ENSPTRP00000029971 GO:0045599 biological_process negative regulation of fat cell differentiation
ENSPTRP00000029971 GO:0045617 biological_process negative regulation of keratinocyte differentiation
ENSPTRP00000029971 GO:0045669 biological_process positive regulation of osteoblast differentiation
ENSPTRP00000029971 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ENSPTRP00000029971 GO:0051795 biological_process positive regulation of catagen
ENSPTRP00000029971 GO:0060346 biological_process bone trabecula formation
ENSPTRP00000029971 GO:0060364 biological_process frontal suture morphogenesis
ENSPTRP00000029971 GO:0060444 biological_process branching involved in mammary gland duct morphogenesis
ENSPTRP00000029971 GO:0061312 biological_process BMP signaling pathway involved in heart development
ENSPTRP00000029971 GO:0070166 biological_process enamel mineralization
ENSPTRP00000029971 GO:0071363 biological_process cellular response to growth factor stimulus
ENSPTRP00000029971 GO:0071392 biological_process cellular response to estradiol stimulus
ENSPTRP00000029971 GO:0090427 biological_process activation of meiosis
ENSPTRP00000029971 GO:2000678 biological_process negative regulation of transcription regulatory region DNA binding
ENSPTRP00000029971 GO:2001055 biological_process positive regulation of mesenchymal cell apoptotic process
ENSPTRP00000029971 GO:0005634 cellular_component nucleus
ENSPTRP00000029971 GO:0005667 cellular_component transcription factor complex
ENSPTRP00000029971 GO:0005737 cellular_component cytoplasm
ENSPTRP00000029971 GO:0003677 molecular_function DNA binding
ENSPTRP00000029971 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPTRP00000029971 GO:0003712 molecular_function transcription cofactor activity
ENSPTRP00000029971 GO:0008134 molecular_function transcription factor binding
ENSPTRP00000029971 GO:0043565 molecular_function sequence-specific DNA binding
ENSPTRP00000029971 GO:0044212 molecular_function transcription regulatory region DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100026817 7425 Nasonia vitripennis 100114980
28377 Anolis carolinensis 100561295 7029 Acyrthosiphon pisum 100575011
61853 Nomascus leucogenys 100581634 400682 Amphimedon queenslandica 100631603
132113 Bombus impatiens 100741791 10029 Cricetulus griseus 100761249
7463 Apis florea 100868820 143995 Megachile rotundata 100881753
9597 Pan paniscus 100987321 39432 Saimiri boliviensis 101033932
9595 Gorilla gorilla 101131683 9669 Mustela putorius furo 101686304
43179 Ictidomys tridecemlineatus 101974502 7897 Latimeria chalumnae 102346883
59463 Myotis lucifugus 102426942 10116 Rattus norvegicus 25483
7227 Drosophila melanogaster 45285 9913 Bos taurus 540230
7070 Tribolium castaneum 641531 9544 Macaca mulatta 694227
9358 Choloepus hoffmanni ENSCHOG00000004913 7719 Ciona intestinalis ENSCING00000009129
9483 Callithrix jacchus ENSCJAG00000019138 10141 Cavia porcellus ENSCPOG00000003596
7955 Danio rerio ENSDARG00000006982 10020 Dipodomys ordii ENSDORG00000008104
9365 Erinaceus europaeus ENSEEUG00000012182 9371 Echinops telfairi ENSETEG00000018267
9685 Felis catus ENSFCAG00000031424 9785 Loxodonta africana ENSLAFG00000031082
9103 Meleagris gallopavo ENSMGAG00000003712 9258 Ornithorhynchus anatinus ENSOANG00000001111
9978 Ochotona princeps ENSOPRG00000007719 7757 Petromyzon marinus ENSPMAG00000003709
9601 Pongo abelii ENSPPYG00000016061 13735 Pelodiscus sinensis ENSPSIG00000010376
8090 Oryzias latipes 100049217 9796 Equus caballus 100058880
30195 Bombus terrestris 100649911 34638 Metaseiulus occidentalis 100900625
9555 Papio anubis 101008621 7460 Apis mellifera 724412
9315 Macropus eugenii ENSMEUG00000005940 132908 Pteropus vampyrus ENSPVAG00000006409
9305 Sarcophilus harrisii ENSSHAG00000009505 37347 Tupaia belangeri ENSTBEG00000014273
9739 Tursiops truncatus ENSTTRG00000015120 8364 Xenopus tropicalis ENSXETG00000009168