Basic Information
Gene ID ENSTRUG00000013090
Gene Name LOC101071462
Full Name Signal transducer and activator of transcription
Organism Takifugu rubripes [31033]

Cross Reference
UniProt H2U8H0 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSTRUP00000033236 Gene3D G3DSA:1.10.238.10 IPR011992 456 573 4.00e-43 EF-hand domain pair
ENSTRUP00000033236 Gene3D G3DSA:1.10.532.10 IPR013799 1 119 1.60e-33 STAT transcription factor, protein interaction
ENSTRUP00000033236 Gene3D G3DSA:1.20.1050.20 IPR013800 139 314 1.30e-46 STAT transcription factor, all-alpha
ENSTRUP00000033236 Gene3D G3DSA:2.60.40.630 IPR012345 315 454 3.90e-50 STAT transcription factor, DNA-binding, subdomain
ENSTRUP00000033236 Gene3D G3DSA:3.30.505.10 IPR000980 574 694 2.00e-41 SH2 domain
ENSTRUP00000033236 PANTHER PTHR11801 IPR001217 2 695 0.00e-00 Transcription factor STAT
ENSTRUP00000033236 Pfam PF00017 IPR000980 570 620 7.30e-09 SH2 domain
ENSTRUP00000033236 Pfam PF01017 IPR013800 138 312 3.90e-40 STAT transcription factor, all-alpha
ENSTRUP00000033236 Pfam PF02864 IPR013801 314 558 2.40e-82 STAT transcription factor, DNA-binding
ENSTRUP00000033236 Pfam PF02865 IPR013799 2 119 6.40e-29 STAT transcription factor, protein interaction
ENSTRUP00000033236 ProSiteProfiles PS50001 IPR000980 565 667 0.00e-00 SH2 domain
ENSTRUP00000033236 SMART SM00252 IPR000980 567 677 2.40e-03 SH2 domain
ENSTRUP00000033236 SMART SM00964 IPR013799 2 122 1.40e-48 STAT transcription factor, protein interaction
ENSTRUP00000033236 SUPERFAMILY SSF47655 IPR015988 138 313 0.00e-00 STAT transcription factor, coiled coil
ENSTRUP00000033236 SUPERFAMILY SSF48092 IPR013799 1 119 0.00e-00 STAT transcription factor, protein interaction
ENSTRUP00000033236 SUPERFAMILY SSF49417 IPR008967 315 560 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSTRUP00000033236 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSTRUP00000033236 PF01017 2e-40 STAT_alpha STAT protein, all-alpha domain
ENSTRUP00000033236 PF02865 6.4e-29 STAT_int STAT protein, protein interaction domain
ENSTRUP00000033236 PF00017 2.2e-09 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSTRUP00000033236 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSTRUP00000033236 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSTRUP00000033236 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSTRUP00000033236 GO:0005634 cellular_component nucleus
ENSTRUP00000033236 GO:0005737 cellular_component cytoplasm
ENSTRUP00000033236 GO:0003677 molecular_function DNA binding
ENSTRUP00000033236 GO:0004871 molecular_function signal transducer activity
ENSTRUP00000033236 GO:0005509 molecular_function calcium ion binding
ENSTRUP00000033236 GO:0019901 molecular_function protein kinase binding
ENSTRUP00000033236 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8083 Xiphophorus maculatus 102236235 69293 Gasterosteus aculeatus ENSGACG00000000707
7897 Latimeria chalumnae ENSLACG00000019027 9315 Macropus eugenii ENSMEUG00000010173
9258 Ornithorhynchus anatinus ENSOANG00000012739 99883 Tetraodon nigroviridis ENSTNIG00000014582