TB Drug Target Database User Guide

• What is TB Drug Target Database ?
• Search Options
• Target Informations
• Target name
• Targeted By
• Function
• Experimental Status
• Molecular Weight
• Protein Analysis
• Isoelectric
• Antigenic Sites
• Tmap
• Pepinfo
• Hydropathy Plot
• Helical Wheel
• Pepplot
• Garnier
• H-T-H
• Secondary Structure
• Amino Acid Sequence   Length
• Pdb Structure
• Amino   acid  Sequence
• Length  of   Nucleotide  Sequence
• Position
• GC   Content
• Nucleotide  Sequence
• Drug Details
• Drug Name
• Synonyms
• Drug Class
• Year of Introduction
• Molecular Target
• Genes Involved in Drug Resistance
• CAS No:
• Route
• Side effects
• Toxicity
• Cost
• Usual Adult Dosage
• Form
• Brand Name
• Manufacturer
• Molecular Formula
• Molecular Weight in g/mol
• Hydrogen Bond Donor Count
• Hydrogen Bond Acceptor Count
• Rotatable Bond Count
• IUPAC Name
• SMILES
• InChI
• References

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What is TB Drug Target Database ?

TB Drug Target Database contains information on the antituberculer drugs, the possible inhibitors recorded in literatures and the target proteins for the treatment of TB. Informations are avilable on the drugs including their Strructural details, also the outputs of the analysis of the target proteins are made available.

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Search Options

In TB Drug Target Database you can search the Target using


• Project TargetId. For eg.Rv2043c for Pyrazinamidase/nicotinamidase.
• Target name keywords will be helpful
• Status of the target For eg:Selected, Cloned, Expressed, Test Target, etc



In TB Drug Target Database you can search the Drug / Inhibitors using


• Drug Name/Ligand Name Synonyms of the drug/inhibitors, Keywords are help ful
• Also you can view the list of drugs / inhibitors available by following the link List of Antitubercular Drugs

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Target Informations

TB Drug Target Database provides the following Information regarding various Targets involved for the available Drugs / Inhibitors.

Target name

The Target name is the name of the protein target for the target sequence.

Targeted By

Targeted By gives the name and link of the Drug / Inhibitor for the given target protein.

Function

Function gives the role of the target protein in Mycobacterium Tuberculosis.

Experimental Status

The status of the target sequence whether it is.


• * Selected
• * Cloned
• * Expressed
• * Soluble
• * Purified
• * Crystallized
• * Diffraction-quality Crystals
• * Diffraction
• * HSQC
• * NMR Assigned
• * Crystal Structure
• * NMR Structure
• * In PDB
• * Work Stopped
• * Test Target
• * Other
.

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