[BiO BB] calculate internal thermodynamic stability profiles

[hongyan wang]

  Hi, All,
   
  Does any body know any free internet-based  software that can give an analysis of internal thermodynamic stability profiles for siRNA/shRNA . I need to assess  the stability of the First Four nucleotides on either end of some siRNA -- perfect matched and mismatched.  S-fold won't give the profile of the end nucleotides and mismatched siRNAs. Thanks very much in advance.
   
  Hongyan Wang
   
   



		
---------------------------------
Brings words and photos together (easily) with
 PhotoMail  - it's free and works with Yahoo! Mail.
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://www.bioinformatics.org/pipermail/bbb/attachments/20060313/3909e340/attachment.html>