[BiO BB] how to identify the function and structure of a novel sequence

Yaoqi Zhou yqzhou at buffalo.edu
Mon Feb 5 11:46:06 EST 2007


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On Feb 2, 2007, at 5:04 PM, Li Xue wrote:

> hello all,
>
> I have a novel sequence(the protein sequence, DNA sequence, the  
> coding sequence, and the cDNA sequence).
>
> I tried BLASTn, BLASTx, and PSI-BLAST with default parameters and  
> modified parameters which loosed the restriction to try to find  
> distantly related matches. What I got are only unknown sequences  
> and hypothetical sequences.
>
> I also tried EBI Interpro with default parameters. No hits.
>
> Can someone offer some ways to identify the function and the  
> structure of  a new sequence? Thank you.
>
> Li
>
>
>
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