> In anycase I wonder why C++ is not a choice of bioinformatics work, > considering now it is pretty portable. But that's the topic of another > discussion. > I correct myself. I found not many, but a few projects. I had a look at one of them libGenome, here in Bioinformatics.org. These projects look promising. There are also libraries for individual file format manupulation. But my original idea is still true, none of these libraries are comprehensive at present. Cheers, Malay