[Proteopedia] New FirstGlance simplified, plus electron density maps

Eric Martz emartz at microbio.umass.edu
Sat Aug 21 20:37:00 EDT 2021


FirstGlance in Jmol <http://firstglance.jmol.org> is linked to every PDB 
entry in Proteopedia. *Educators* please note that FirstGlance enables 
exploration of protein structure with remarkable ease of use. A *new 
version*, just released, starts out in a "less detailed" or *simplified 
mode* for beginners. See secondary structure, hydrophobic cores, 
distribution of charges, salt bridges, cation-pi interactions, disulfide 
bonds and 6 other kinds of protein crosslinks with a few clicks each. 
Links go to explanations and illustrations of each of these in 
Proteopedia.Org 
<https://proteopedia.org/w/About_Macromolecular_Structure>. See 
non-covalent interactions with ligands. Isolate any moiety or hide 
components with a few clicks. Find by short sequence motifs, sequence 
numbers, etc.

Any view can be saved with a few clicks either as a static image, or as 
an animation ready to drop into a presentation slide (see examples 
<http://tinyurl.com/movingmolecules>). Excellent for student reports 
(see lesson plans 
<https://proteopedia.org/w/User:Eric_Martz/Introduction_to_Structural_Bioinformatics>). 


FirstGlance displays amino acid sequences and provides instructions 
<https://proteopedia.org/wiki/fgij/seqalign.htm> for doing multiple 
sequence alignments and clear visualization with MSAReveal.Org 
<http://msareveal.org>.

Press "Show more details" if you're up for any of: electron density maps 
<https://proteopedia.org/w/Electron_density_maps> (new and super easy), 
alternate locations (easily animated 
<https://proteopedia.org/w/Alternate_locations>), occupancy values, 
crystal contacts or the unit cell. See FirstGlance-generated animations 
of electron density maps 
<https://docs.google.com/presentation/d/1t-hAL5AWeGmXJdanNNusIbiLN0_c53laQe7PJrjQRe8/edit#slide=id.gead9198f4d_0_60>.

Please feel free to reply with questions or suggestions.

-Eric Martz

P.S. If problems with the new version, hold down the Shift key while 
reloading the page to force the browser's cache to update.

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