Metazoan Taxonomic Class

Embryomic development of Homo sapiens

All human beings are developed from fertilized eggs that about 100 m in diameter. What happens during this process? Which regulators control the development process? In our laboratory, we are working on mechanisms how eggs develop into a well organized adult body using both experimental and bioinformatics approaches. Two kinds of regulators we focused on are maternal factors and transcription factor.


Maternal factors of Homo sapiens and Mus musculus

Due to the limited microarray data, maternal factors specifically expressed in eggs are avalible only for Homo sapiens and Mus musculus currently.


Transcription factors grouped by Pfam DBD
AF-4 Androgen recep ARID AT hook Basic BTB
BTD bZIP 1 bZIP 2 CBFB NFYA CBFD NFYB HMF CG-1
CP2 CSD CTF NFI CUT DM E2F TDP
Ets ETS PEA3 N Fork head GAGA GATA GCM
GCR GTF2I HLH HMG box Homeobox Hormone recep
HPD HSF DNA-bind HTH psq IRF IRF-3 LAG1-DNAbind
MBD MH1 Myb DNA-binding Myc N NDT80 PhoG Nrf1 DNA-bind
Oest recep P53 PAX PBC Pou Prog receptor
RFX DNA binding RHD Runt SAND SCAN SIM C
SRF-TF STAT1 TAZ2bind STAT alpha STAT bind STAT int STE
T-box TAFH TEA TF AP-2 TF Otx THAP
TIG TSC22 Tub Vert HS TF zf-BED zf-C2H2
zf-C2HC zf-C4 zf-LITAF-like zf-MIZ zf-NF-X1 Zn clus
Others

All other potential transcription factors are categorized into 'others'.