Basic Information
Gene ID 100049268
Gene Name wt1; Wt1a
Full Name Wilms' tumor suppressor 1
Organism Oryzias latipes [8090]

Cross Reference
UniProt Q8JIR9 UniGene Ola.169
PDB NULL OMIM NULL
KEGG ola:100049268 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 8090.ENSORLP00000015554

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSORLP00000015559 Gene3D G3DSA:3.30.160.60 IPR013087 275 304 1.90e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSORLP00000015559 Gene3D G3DSA:3.30.160.60 IPR013087 305 335 4.30e-18 Zinc finger C2H2-type/integrase DNA-binding domain
ENSORLP00000015559 Gene3D G3DSA:3.30.160.60 IPR013087 336 369 9.10e-16 Zinc finger C2H2-type/integrase DNA-binding domain
ENSORLP00000015559 Gene3D G3DSA:3.30.160.60 IPR013087 371 399 5.80e-10 Zinc finger C2H2-type/integrase DNA-binding domain
ENSORLP00000015559 Pfam PF00096 IPR007087 375 399 6.30e-03 Zinc finger, C2H2
ENSORLP00000015559 Pfam PF02165 IPR000976 1 229 3.60e-103 Wilm's tumour protein, N-terminal
ENSORLP00000015559 Pfam PF02165 IPR000976 228 282 1.90e-24 Wilm's tumour protein, N-terminal
ENSORLP00000015559 PRINTS PR00049 IPR017987 1 17 2.60e-08 Wilm's tumour protein
ENSORLP00000015559 PRINTS PR00049 IPR017987 19 35 2.60e-08 Wilm's tumour protein
ENSORLP00000015559 ProSitePatterns PS00028 IPR007087 286 308 - Zinc finger, C2H2
ENSORLP00000015559 ProSitePatterns PS00028 IPR007087 316 338 - Zinc finger, C2H2
ENSORLP00000015559 ProSitePatterns PS00028 IPR007087 346 366 - Zinc finger, C2H2
ENSORLP00000015559 ProSitePatterns PS00028 IPR007087 377 399 - Zinc finger, C2H2
ENSORLP00000015559 ProSiteProfiles PS50157 IPR007087 284 313 0.00e-00 Zinc finger, C2H2
ENSORLP00000015559 ProSiteProfiles PS50157 IPR007087 314 343 0.00e-00 Zinc finger, C2H2
ENSORLP00000015559 ProSiteProfiles PS50157 IPR007087 344 371 0.00e-00 Zinc finger, C2H2
ENSORLP00000015559 ProSiteProfiles PS50157 IPR007087 375 404 0.00e-00 Zinc finger, C2H2
ENSORLP00000015559 SMART SM00355 IPR015880 284 308 4.40e-04 Zinc finger, C2H2-like
ENSORLP00000015559 SMART SM00355 IPR015880 314 338 1.50e-07 Zinc finger, C2H2-like
ENSORLP00000015559 SMART SM00355 IPR015880 344 366 6.80e-05 Zinc finger, C2H2-like
ENSORLP00000015559 SMART SM00355 IPR015880 375 399 5.20e-05 Zinc finger, C2H2-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSORLP00000015559 PF02165 0 WT1 Wilm's tumour protein
ENSORLP00000015559 PF00096 1.7e-17 zf-C2H2 Zinc finger, C2H2 type
ENSORLP00000015559 PF13465 1.4e-16 zf-H2C2_2 Zinc-finger double domain
ENSORLP00000015559 PF13894 3.5e-10 zf-C2H2_4 C2H2-type zinc finger

Gene Ontology Annotation
Protein Entry Name Space Description
ENSORLP00000015559 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSORLP00000015559 GO:0006351 biological_process transcription, DNA-templated
ENSORLP00000015559 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSORLP00000015559 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSORLP00000015559 GO:0005634 cellular_component nucleus
ENSORLP00000015559 GO:0005737 cellular_component cytoplasm
ENSORLP00000015559 GO:0016607 cellular_component nuclear speck
ENSORLP00000015559 GO:0003676 molecular_function nucleic acid binding
ENSORLP00000015559 GO:0003677 molecular_function DNA binding
ENSORLP00000015559 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSORLP00000015559 GO:0003723 molecular_function RNA binding
ENSORLP00000015559 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
59729 Taeniopygia guttata 100222371 9597 Pan paniscus 100974201
39432 Saimiri boliviensis 101027475 7897 Latimeria chalumnae 102355188
7955 Danio rerio 30245 9615 Canis familiaris ENSCAFG00000007426
9483 Callithrix jacchus ENSCJAG00000005900 9361 Dasypus novemcinctus ENSDNOG00000003652
10020 Dipodomys ordii ENSDORG00000013725 9796 Equus caballus ENSECAG00000022308
9365 Erinaceus europaeus ENSEEUG00000007221 9371 Echinops telfairi ENSETEG00000000684
9685 Felis catus ENSFCAG00000000308 9103 Meleagris gallopavo ENSMGAG00000001489
13616 Monodelphis domestica ENSMODG00000009646 9669 Mustela putorius furo ENSMPUG00000011307
30611 Otolemur garnettii ENSOGAG00000007118 8128 Oreochromis niloticus ENSONIG00000011043
42254 Sorex araneus ENSSARG00000000207 9305 Sarcophilus harrisii ENSSHAG00000017390
9823 Sus scrofa ENSSSCG00000013316 43179 Ictidomys tridecemlineatus ENSSTOG00000023716
30538 Vicugna pacos ENSVPAG00000007788 10029 Cricetulus griseus 100767732
28377 Anolis carolinensis ENSACAG00000002480 9646 Ailuropoda melanoleuca ENSAMEG00000006957
9913 Bos taurus ENSBTAG00000047268 69293 Gasterosteus aculeatus ENSGACG00000003299
9031 Gallus gallus ENSGALG00000012115 9595 Gorilla gorilla ENSGGOG00000011586
9785 Loxodonta africana ENSLAFG00000006160 30608 Microcebus murinus ENSMICG00000004097
59463 Myotis lucifugus ENSMLUG00000027523 9544 Macaca mulatta ENSMMUG00000009881
10090 Mus musculus ENSMUSG00000016458 61853 Nomascus leucogenys ENSNLEG00000017890
9258 Ornithorhynchus anatinus ENSOANG00000015147 9986 Oryctolagus cuniculus ENSOCUG00000005882
9978 Ochotona princeps ENSOPRG00000015709 9813 Procavia capensis ENSPCAG00000002213
7757 Petromyzon marinus ENSPMAG00000008950 9601 Pongo abelii ENSPPYG00000029822
13735 Pelodiscus sinensis ENSPSIG00000013679 9598 Pan troglodytes ENSPTRG00000003476
132908 Pteropus vampyrus ENSPVAG00000006895 37347 Tupaia belangeri ENSTBEG00000007282
99883 Tetraodon nigroviridis ENSTNIG00000007794 9739 Tursiops truncatus ENSTTRG00000012819
8364 Xenopus tropicalis ENSXETG00000008172 8083 Xiphophorus maculatus ENSXMAG00000005139