Basic Information
Gene ID 100468516
Gene Name TP53
Full Name Cellular tumor antigen p53
Organism Ailuropoda melanoleuca [9646]

Cross Reference
UniProt G1MEP6 UniGene NULL
PDB NULL OMIM NULL
KEGG aml:100468516 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_002924483 Gene3D G3DSA:2.60.40.720 IPR012346 81 283 2.00e-96 p53/RUNT-type transcription factor, DNA-binding domain
XP_002924483 Gene3D G3DSA:4.10.170.10 IPR010991 307 347 7.90e-20 p53, tetramerisation domain
XP_002924483 PANTHER PTHR11447 IPR002117 1 381 0.00e-00 p53 tumour suppressor family
XP_002924483 Pfam PF00870 IPR011615 82 276 1.60e-108 p53, DNA-binding domain
XP_002924483 Pfam PF07710 IPR010991 307 346 7.50e-18 p53, tetramerisation domain
XP_002924483 Pfam PF08563 IPR013872 5 29 2.30e-11 p53 transactivation domain
XP_002924483 PRINTS PR00386 IPR002117 103 129 1.70e-85 p53 tumour suppressor family
XP_002924483 PRINTS PR00386 IPR002117 145 166 1.70e-85 p53 tumour suppressor family
XP_002924483 PRINTS PR00386 IPR002117 201 222 1.70e-85 p53 tumour suppressor family
XP_002924483 PRINTS PR00386 IPR002117 224 246 1.70e-85 p53 tumour suppressor family
XP_002924483 PRINTS PR00386 IPR002117 252 274 1.70e-85 p53 tumour suppressor family
XP_002924483 PRINTS PR00386 IPR002117 314 338 1.70e-85 p53 tumour suppressor family
XP_002924483 ProSitePatterns PS00348 IPR002117 225 237 - p53 tumour suppressor family
XP_002924483 SUPERFAMILY SSF47719 IPR010991 307 346 0.00e-00 p53, tetramerisation domain
XP_002924483 SUPERFAMILY SSF49417 IPR008967 84 275 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_002924483 PF00870 0 P53 P53 DNA-binding domain
XP_002924483 PF07710 3.6e-18 P53_tetramer P53 tetramerisation motif
XP_002924483 PF08563 8.9e-12 P53_TAD P53 transactivation motif

Gene Ontology Annotation
Protein Entry Name Space Description
XP_002924483 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
XP_002924483 GO:0000733 biological_process DNA strand renaturation
XP_002924483 GO:0006289 biological_process nucleotide-excision repair
XP_002924483 GO:0006351 biological_process transcription, DNA-templated
XP_002924483 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_002924483 GO:0006915 biological_process apoptotic process
XP_002924483 GO:0006978 biological_process DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
XP_002924483 GO:0007049 biological_process cell cycle
XP_002924483 GO:0007275 biological_process multicellular organismal development
XP_002924483 GO:0007569 biological_process cell aging
XP_002924483 GO:0010165 biological_process response to X-ray
XP_002924483 GO:0010332 biological_process response to gamma radiation
XP_002924483 GO:0012501 biological_process programmed cell death
XP_002924483 GO:0030308 biological_process negative regulation of cell growth
XP_002924483 GO:0031065 biological_process positive regulation of histone deacetylation
XP_002924483 GO:0034644 biological_process cellular response to UV
XP_002924483 GO:0042771 biological_process intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
XP_002924483 GO:0043525 biological_process positive regulation of neuron apoptotic process
XP_002924483 GO:0051262 biological_process protein tetramerization
XP_002924483 GO:0090200 biological_process positive regulation of release of cytochrome c from mitochondria
XP_002924483 GO:0097252 biological_process oligodendrocyte apoptotic process
XP_002924483 GO:0005634 cellular_component nucleus
XP_002924483 GO:0005657 cellular_component replication fork
XP_002924483 GO:0005730 cellular_component nucleolus
XP_002924483 GO:0005737 cellular_component cytoplasm
XP_002924483 GO:0005739 cellular_component mitochondrion
XP_002924483 GO:0005759 cellular_component mitochondrial matrix
XP_002924483 GO:0005783 cellular_component endoplasmic reticulum
XP_002924483 GO:0005829 cellular_component cytosol
XP_002924483 GO:0003677 molecular_function DNA binding
XP_002924483 GO:0003682 molecular_function chromatin binding
XP_002924483 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_002924483 GO:0005507 molecular_function copper ion binding
XP_002924483 GO:0005524 molecular_function ATP binding
XP_002924483 GO:0044212 molecular_function transcription regulatory region DNA binding
XP_002924483 GO:0046872 molecular_function metal ion binding