Basic Information
Gene ID 100606638
Gene Name EPAS1
Full Name Uncharacterized protein
Organism Nomascus leucogenys [61853]

Cross Reference
UniProt G1S4V4 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003262854 Pfam PF00989 IPR013767 101 171 4.90e-05 PAS fold
XP_003262854 Pfam PF08778 IPR014887 838 877 3.30e-20 HIF-1 alpha, transactivation domain, C-terminal
XP_003262854 Pfam PF11413 IPR021537 524 556 9.50e-18 Hypoxia-inducible factor, alpha subunit
XP_003262854 PRINTS PR00785 IPR001067 109 128 9.40e-07 Nuclear translocator
XP_003262854 PRINTS PR00785 IPR001067 251 268 9.40e-07 Nuclear translocator
XP_003262854 PRINTS PR00785 IPR001067 57 77 9.40e-07 Nuclear translocator
XP_003262854 ProSiteProfiles PS50112 IPR000014 100 155 0.00e-00 PAS domain
XP_003262854 ProSiteProfiles PS50112 IPR000014 257 308 0.00e-00 PAS domain
XP_003262854 ProSiteProfiles PS50888 IPR011598 22 75 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003262854 SMART SM00086 IPR001610 312 355 2.20e-11 PAC motif
XP_003262854 SMART SM00091 IPR000014 240 306 3.70e-10 PAS domain
XP_003262854 SMART SM00091 IPR000014 94 160 1.50e-11 PAS domain
XP_003262854 SMART SM00353 IPR011598 28 83 1.30e-11 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003262854 SUPERFAMILY SSF47459 IPR011598 19 80 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003262854 SUPERFAMILY SSF55785 IPR000014 103 209 0.00e-00 PAS domain
XP_003262854 SUPERFAMILY SSF55785 IPR000014 252 354 0.00e-00 PAS domain
XP_003262854 TIGRFAM TIGR00229 IPR000014 106 158 1.00e-05 PAS domain
XP_003262854 TIGRFAM TIGR00229 IPR000014 260 336 6.90e-08 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003262854 PF14598 2.4e-28 PAS_11 PAS domain
XP_003262854 PF08447 4.6e-25 PAS_3 PAS fold
XP_003262854 PF08778 1.7e-20 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
XP_003262854 PF11413 4.4e-18 HIF-1 Hypoxia-inducible factor-1
XP_003262854 PF00989 3.9e-14 PAS PAS fold
XP_003262854 PF13426 1.1e-10 PAS_9 PAS domain
XP_003262854 PF08448 1.1e-07 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003262854 GO:0001666 biological_process response to hypoxia
XP_003262854 GO:0045893 biological_process positive regulation of transcription, DNA-templated
XP_003262854 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
XP_003262854 GO:0071456 biological_process cellular response to hypoxia
XP_003262854 GO:0005634 cellular_component nucleus
XP_003262854 GO:0005737 cellular_component cytoplasm
XP_003262854 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_003262854 GO:0004871 molecular_function signal transducer activity
XP_003262854 GO:0035035 molecular_function histone acetyltransferase binding