Basic Information
Gene ID 100935401
Gene Name ESR1
Full Name Estrogen receptor
Organism Sarcophilus harrisii [9305]

Cross Reference
UniProt G3WR97 UniGene NULL
PDB NULL OMIM NULL
KEGG shr:100935401 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003769593 Gene3D G3DSA:1.10.565.10 IPR008946 233 263 4.30e-100 Nuclear hormone receptor, ligand-binding
XP_003769593 Gene3D G3DSA:1.10.565.10 IPR008946 305 542 4.30e-100 Nuclear hormone receptor, ligand-binding
XP_003769593 Gene3D G3DSA:3.30.50.10 IPR013088 179 232 9.50e-28 Zinc finger, NHR/GATA-type
XP_003769593 Pfam PF00104 IPR000536 321 518 9.20e-30 Nuclear hormone receptor, ligand-binding, core
XP_003769593 Pfam PF00105 IPR001628 178 246 2.20e-31 Zinc finger, nuclear hormone receptor-type
XP_003769593 Pfam PF02159 IPR001292 42 175 5.70e-50 Oestrogen receptor
XP_003769593 Pfam PF12743 IPR024736 546 588 6.00e-23 Oestrogen-type nuclear receptor final C-terminal domain
XP_003769593 PIRSF PIRSF002527 IPR024178 42 583 1.80e-294 Oestrogen receptor/oestrogen-related receptor
XP_003769593 PIRSF PIRSF500101 IPR001292 1 588 0.00e-00 Oestrogen receptor
XP_003769593 PRINTS PR00047 IPR001628 179 195 7.80e-17 Zinc finger, nuclear hormone receptor-type
XP_003769593 PRINTS PR00047 IPR001628 195 210 7.80e-17 Zinc finger, nuclear hormone receptor-type
XP_003769593 PRINTS PR00047 IPR001628 228 236 7.80e-17 Zinc finger, nuclear hormone receptor-type
XP_003769593 PRINTS PR00047 IPR001628 236 244 7.80e-17 Zinc finger, nuclear hormone receptor-type
XP_003769593 PRINTS PR00398 IPR001723 240 250 5.40e-27 Steroid hormone receptor
XP_003769593 PRINTS PR00398 IPR001723 343 364 5.40e-27 Steroid hormone receptor
XP_003769593 PRINTS PR00398 IPR001723 364 380 5.40e-27 Steroid hormone receptor
XP_003769593 PRINTS PR00398 IPR001723 432 447 5.40e-27 Steroid hormone receptor
XP_003769593 PRINTS PR00398 IPR001723 500 517 5.40e-27 Steroid hormone receptor
XP_003769593 PRINTS PR00543 IPR001292 110 126 3.40e-69 Oestrogen receptor
XP_003769593 PRINTS PR00543 IPR001292 127 146 3.40e-69 Oestrogen receptor
XP_003769593 PRINTS PR00543 IPR001292 148 167 3.40e-69 Oestrogen receptor
XP_003769593 PRINTS PR00543 IPR001292 26 43 3.40e-69 Oestrogen receptor
XP_003769593 PRINTS PR00543 IPR001292 45 62 3.40e-69 Oestrogen receptor
XP_003769593 PRINTS PR00543 IPR001292 6 24 3.40e-69 Oestrogen receptor
XP_003769593 PRINTS PR00543 IPR001292 67 82 3.40e-69 Oestrogen receptor
XP_003769593 PRINTS PR00543 IPR001292 92 106 3.40e-69 Oestrogen receptor
XP_003769593 ProSitePatterns PS00031 IPR001628 179 205 - Zinc finger, nuclear hormone receptor-type
XP_003769593 ProSiteProfiles PS51030 IPR001628 176 251 0.00e-00 Zinc finger, nuclear hormone receptor-type
XP_003769593 SMART SM00399 IPR001628 176 247 6.40e-40 Zinc finger, nuclear hormone receptor-type
XP_003769593 SMART SM00430 IPR000536 342 512 3.30e-37 Nuclear hormone receptor, ligand-binding, core
XP_003769593 SUPERFAMILY SSF48508 IPR008946 300 541 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003769593 PF02159 0 Oest_recep Oestrogen receptor
XP_003769593 PF00105 1.3e-31 zf-C4 Zinc finger, C4 type (two domains)
XP_003769593 PF00104 5.8e-30 Hormone_recep Ligand-binding domain of nuclear hormone receptor
XP_003769593 PF12743 2.5e-23 ESR1_C Oestrogen-type nuclear receptor final C-terminal

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003769593 GO:0006351 biological_process transcription, DNA-templated
XP_003769593 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_003769593 GO:0007200 biological_process phospholipase C-activating G-protein coupled receptor signaling pathway
XP_003769593 GO:0007204 biological_process positive regulation of cytosolic calcium ion concentration
XP_003769593 GO:0010863 biological_process positive regulation of phospholipase C activity
XP_003769593 GO:0030518 biological_process intracellular steroid hormone receptor signaling pathway
XP_003769593 GO:0043124 biological_process negative regulation of I-kappaB kinase/NF-kappaB signaling
XP_003769593 GO:0043433 biological_process negative regulation of sequence-specific DNA binding transcription factor activity
XP_003769593 GO:0045429 biological_process positive regulation of nitric oxide biosynthetic process
XP_003769593 GO:0051000 biological_process positive regulation of nitric-oxide synthase activity
XP_003769593 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
XP_003769593 GO:0071392 biological_process cellular response to estradiol stimulus
XP_003769593 GO:0005634 cellular_component nucleus
XP_003769593 GO:0005794 cellular_component Golgi apparatus
XP_003769593 GO:0005886 cellular_component plasma membrane
XP_003769593 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_003769593 GO:0003707 molecular_function steroid hormone receptor activity
XP_003769593 GO:0005496 molecular_function steroid binding
XP_003769593 GO:0008270 molecular_function zinc ion binding
XP_003769593 GO:0030284 molecular_function estrogen receptor activity
XP_003769593 GO:0043565 molecular_function sequence-specific DNA binding