Basic Information
Gene ID 100971244
Gene Name EZH2
Full Name PREDICTED: histone-lysine N-methyltransferase EZH2 isoform 1 [Panpaniscus].
Organism Pan paniscus [9597]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003820556 Pfam PF00856 IPR001214 631 734 1.30e-22 SET domain
XP_003820556 Pfam PF11616 IPR021654 47 76 6.80e-19 WD repeat binding protein EZH2
XP_003820556 ProSiteProfiles PS50280 IPR001214 620 735 0.00e-00 SET domain
XP_003820556 ProSiteProfiles PS51633 IPR026489 511 613 0.00e-00 CXC domain
XP_003820556 SMART SM00317 IPR001214 620 741 2.10e-40 SET domain
XP_003820556 SMART SM00717 IPR001005 167 258 1.70e-05 SANT/Myb domain
XP_003820556 SMART SM00717 IPR001005 436 484 3.30e-03 SANT/Myb domain

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003820556 PF00856 1.3e-22 SET SET domain
XP_003820556 PF11616 3.1e-19 EZH2_WD-Binding WD repeat binding protein EZH2

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003820556 GO:0006351 biological_process transcription, DNA-templated
XP_003820556 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_003820556 GO:0005634 cellular_component nucleus
XP_003820556 GO:0035098 cellular_component ESC/E(Z) complex
XP_003820556 GO:0003682 molecular_function chromatin binding
XP_003820556 GO:0018024 molecular_function histone-lysine N-methyltransferase activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9986 Oryctolagus cuniculus 100345157 30195 Bombus terrestris 100647736
7029 Acyrthosiphon pisum 100168406 9823 Sus scrofa 100625497
132113 Bombus impatiens 100747000 10029 Cricetulus griseus 100758055
143995 Megachile rotundata 100883902 9555 Papio anubis 101001043
9031 Gallus gallus 420784 9615 Canis familiaris 475511
9598 Pan troglodytes 745437 28377 Anolis carolinensis ENSACAG00000013910
9483 Callithrix jacchus ENSCJAG00000016360 10141 Cavia porcellus ENSCPOG00000003710
8049 Gadus morhua ENSGMOG00000015628 9785 Loxodonta africana ENSLAFG00000001578
30608 Microcebus murinus ENSMICG00000011127 9544 Macaca mulatta ENSMMUG00000013494
13616 Monodelphis domestica ENSMODG00000001852 61853 Nomascus leucogenys ENSNLEG00000003596
9978 Ochotona princeps ENSOPRG00000007788 9601 Pongo abelii ENSPPYG00000018147
9305 Sarcophilus harrisii ENSSHAG00000017743 37347 Tupaia belangeri ENSTBEG00000015636
59729 Taeniopygia guttata ENSTGUG00000001770 99883 Tetraodon nigroviridis ENSTNIG00000001024
9478 Tarsius syrichta ENSTSYG00000000831 30538 Vicugna pacos ENSVPAG00000001437
8364 Xenopus tropicalis ENSXETG00000020146 39432 Saimiri boliviensis 101051611
43179 Ictidomys tridecemlineatus 101968825 9358 Choloepus hoffmanni ENSCHOG00000013009
51511 Ciona savignyi ENSCSAVG00000002002 9361 Dasypus novemcinctus ENSDNOG00000013912
10020 Dipodomys ordii ENSDORG00000007731 9685 Felis catus ENSFCAG00000008618
9595 Gorilla gorilla ENSGGOG00000014846 59463 Myotis lucifugus ENSMLUG00000002498
9669 Mustela putorius furo ENSMPUG00000007249 9258 Ornithorhynchus anatinus ENSOANG00000000279
30611 Otolemur garnettii ENSOGAG00000010387 13735 Pelodiscus sinensis ENSPSIG00000014933
31033 Takifugu rubripes ENSTRUG00000015011