Basic Information
Gene ID 100981036
Gene Name IRX3
Full Name PREDICTED: iroquois-class homeodomain protein IRX-3 [Pan paniscus].
Organism Pan paniscus [9597]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003811607 Gene3D G3DSA:1.10.10.60 IPR009057 146 215 2.70e-25 Homeodomain-like
XP_003811607 Pfam PF05920 IPR008422 161 200 3.50e-14 Homeobox KN domain
XP_003811607 ProSitePatterns PS00027 IPR017970 179 202 - Homeobox, conserved site
XP_003811607 ProSiteProfiles PS50071 IPR001356 151 204 0.00e-00 Homeobox domain
XP_003811607 SMART SM00389 IPR001356 144 208 1.40e-14 Homeobox domain
XP_003811607 SMART SM00548 IPR003893 358 375 9.20e-09 Iroquois-class homeodomain protein
XP_003811607 SUPERFAMILY SSF46689 IPR009057 148 211 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003811607 PF05920 1.9e-14 Homeobox_KN Homeobox KN domain
XP_003811607 PF00046 3.7e-07 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003811607 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
XP_003811607 GO:0006351 biological_process transcription, DNA-templated
XP_003811607 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_003811607 GO:0007275 biological_process multicellular organismal development
XP_003811607 GO:0007399 biological_process nervous system development
XP_003811607 GO:0007420 biological_process brain development
XP_003811607 GO:0009953 biological_process dorsal/ventral pattern formation
XP_003811607 GO:0030154 biological_process cell differentiation
XP_003811607 GO:0045893 biological_process positive regulation of transcription, DNA-templated
XP_003811607 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
XP_003811607 GO:0005634 cellular_component nucleus
XP_003811607 GO:0003677 molecular_function DNA binding
XP_003811607 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_003811607 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9555 Papio anubis 101011296 9669 Mustela putorius furo 101673132
9615 Canis familiaris 487277 9796 Equus caballus ENSECAG00000023496
9371 Echinops telfairi ENSETEG00000020300 30611 Otolemur garnettii ENSOGAG00000029236
9601 Pongo abelii ENSPPYG00000007354 9305 Sarcophilus harrisii ENSSHAG00000012619
9823 Sus scrofa ENSSSCG00000002831 37347 Tupaia belangeri ENSTBEG00000008254
39432 Saimiri boliviensis 101051438 9646 Ailuropoda melanoleuca ENSAMEG00000016409
10141 Cavia porcellus ENSCPOG00000008794 9361 Dasypus novemcinctus ENSDNOG00000012985
10020 Dipodomys ordii ENSDORG00000011798 9595 Gorilla gorilla ENSGGOG00000014067
9315 Macropus eugenii ENSMEUG00000014864 30608 Microcebus murinus ENSMICG00000016860
9544 Macaca mulatta ENSMMUG00000001389 61853 Nomascus leucogenys ENSNLEG00000001184
9813 Procavia capensis ENSPCAG00000007496 9598 Pan troglodytes ENSPTRG00000008120
132908 Pteropus vampyrus ENSPVAG00000015986 43179 Ictidomys tridecemlineatus ENSSTOG00000019902

Paralogs
100988951