Basic Information
Gene ID 11279 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name KLF8; BKLF3, ZNF741
Full Name Krueppel-like factor 8
Organism Homo sapiens [9606]

Cross Reference
UniProt O95600 UniGene Hs.646614
PDB NULL OMIM 300286
KEGG hsa:11279 UCSC uc011mop.2

Protein Interactions
DIP NULL
IntAct O95600
MINT MINT-7969747
STRING 9606.ENSP00000417303

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000417303 Gene3D G3DSA:3.30.160.60 IPR013087 269 294 3.20e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000417303 Gene3D G3DSA:3.30.160.60 IPR013087 295 325 4.60e-20 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000417303 Gene3D G3DSA:3.30.160.60 IPR013087 326 356 9.10e-11 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000417303 ProSitePatterns PS00028 IPR007087 276 298 - Zinc finger, C2H2
ENSP00000417303 ProSitePatterns PS00028 IPR007087 306 328 - Zinc finger, C2H2
ENSP00000417303 ProSitePatterns PS00028 IPR007087 336 356 - Zinc finger, C2H2
ENSP00000417303 ProSiteProfiles PS50157 IPR007087 274 303 0.00e-00 Zinc finger, C2H2
ENSP00000417303 ProSiteProfiles PS50157 IPR007087 304 333 0.00e-00 Zinc finger, C2H2
ENSP00000417303 ProSiteProfiles PS50157 IPR007087 334 359 0.00e-00 Zinc finger, C2H2
ENSP00000417303 SMART SM00355 IPR015880 274 298 4.10e-05 Zinc finger, C2H2-like
ENSP00000417303 SMART SM00355 IPR015880 304 328 3.00e-07 Zinc finger, C2H2-like
ENSP00000417303 SMART SM00355 IPR015880 334 356 1.90e-05 Zinc finger, C2H2-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000417303 PF00096 7.4e-13 zf-C2H2 Zinc finger, C2H2 type
ENSP00000417303 PF13465 1.9e-11 zf-H2C2_2 Zinc-finger double domain
ENSP00000417303 PF13894 2.7e-08 zf-C2H2_4 C2H2-type zinc finger

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000417303 GO:0005634 cellular_component nucleus
ENSP00000417303 GO:0003677 molecular_function DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9258 Ornithorhynchus anatinus 100073693 7425 Nasonia vitripennis 100115031
10224 Saccoglossus kowalevskii 100368725 9601 Pongo abelii 100442771
30195 Bombus terrestris 100643418 132113 Bombus impatiens 100745798
10029 Cricetulus griseus 100751247 7463 Apis florea 100871278
143995 Megachile rotundata 100881458 34638 Metaseiulus occidentalis 100908396
9597 Pan paniscus 100983920 9555 Papio anubis 100997551
8083 Xiphophorus maculatus 102219801 7897 Latimeria chalumnae 102350431
13735 Pelodiscus sinensis 102457138 7029 Acyrthosiphon pisum 100159231
61853 Nomascus leucogenys 100580000 8128 Oreochromis niloticus 100704719
39432 Saimiri boliviensis 101050744 6087 Hydra magnipapillata 101241620
9031 Gallus gallus 418817 7460 Apis mellifera 552397
7070 Tribolium castaneum 660309 28377 Anolis carolinensis ENSACAG00000006389
9646 Ailuropoda melanoleuca ENSAMEG00000012545 9913 Bos taurus ENSBTAG00000044007
9615 Canis familiaris ENSCAFG00000016508 7955 Danio rerio ENSDARG00000032197
10020 Dipodomys ordii ENSDORG00000015820 9796 Equus caballus ENSECAG00000016062
9371 Echinops telfairi ENSETEG00000016171 9785 Loxodonta africana ENSLAFG00000016849
8090 Oryzias latipes ENSORLG00000015374 9305 Sarcophilus harrisii ENSSHAG00000002694
31033 Takifugu rubripes ENSTRUG00000009714 8364 Xenopus tropicalis ENSXETG00000009616
7227 Drosophila melanogaster FBgn0261705 6239 Caenorhabditis elegans 186179
10090 Mus musculus 245671 7668 Strongylocentrotus purpuratus 574751
9358 Choloepus hoffmanni ENSCHOG00000003950 7719 Ciona intestinalis ENSCING00000014976
9483 Callithrix jacchus ENSCJAG00000007304 10141 Cavia porcellus ENSCPOG00000010165
51511 Ciona savignyi ENSCSAVG00000002903 9365 Erinaceus europaeus ENSEEUG00000014292
9685 Felis catus ENSFCAG00000012644 69293 Gasterosteus aculeatus ENSGACG00000001883
9595 Gorilla gorilla ENSGGOG00000008188 8049 Gadus morhua ENSGMOG00000019561
9315 Macropus eugenii ENSMEUG00000003709 9103 Meleagris gallopavo ENSMGAG00000014947
30608 Microcebus murinus ENSMICG00000001146 59463 Myotis lucifugus ENSMLUG00000016695
9544 Macaca mulatta ENSMMUG00000014678 13616 Monodelphis domestica ENSMODG00000010883
9669 Mustela putorius furo ENSMPUG00000000194 9986 Oryctolagus cuniculus ENSOCUG00000004244
30611 Otolemur garnettii ENSOGAG00000013642 9978 Ochotona princeps ENSOPRG00000009033
7757 Petromyzon marinus ENSPMAG00000001851 9598 Pan troglodytes ENSPTRG00000005929
132908 Pteropus vampyrus ENSPVAG00000000264 10116 Rattus norvegicus ENSRNOG00000009145
42254 Sorex araneus ENSSARG00000013181 9823 Sus scrofa ENSSSCG00000009462
43179 Ictidomys tridecemlineatus ENSSTOG00000012012 37347 Tupaia belangeri ENSTBEG00000016621
59729 Taeniopygia guttata ENSTGUG00000005539 99883 Tetraodon nigroviridis ENSTNIG00000004690
9478 Tarsius syrichta ENSTSYG00000011477 9739 Tursiops truncatus ENSTTRG00000008773
30538 Vicugna pacos ENSVPAG00000000179