Basic Information
Gene ID 114109 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Nkx2-5; Csx, Nkx-2.5, Nkx2e
Full Name Homeobox protein Nkx-2.5
Organism Rattus norvegicus [10116]

Cross Reference
UniProt O35767 UniGene Rn.6179
PDB NULL OMIM NULL
KEGG rno:114109 UCSC RGD:620520

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 10116.ENSRNOP00000028155

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSRNOP00000028155 Gene3D G3DSA:1.10.10.60 IPR009057 123 198 2.00e-26 Homeodomain-like
ENSRNOP00000028155 Pfam PF00046 IPR001356 138 194 7.80e-21 Homeobox domain
ENSRNOP00000028155 PRINTS PR00024 IPR020479 159 170 1.70e-06 Homeodomain, metazoa
ENSRNOP00000028155 PRINTS PR00024 IPR020479 174 184 1.70e-06 Homeodomain, metazoa
ENSRNOP00000028155 PRINTS PR00024 IPR020479 184 193 1.70e-06 Homeodomain, metazoa
ENSRNOP00000028155 ProSitePatterns PS00027 IPR017970 170 193 - Homeobox, conserved site
ENSRNOP00000028155 ProSiteProfiles PS50071 IPR001356 135 195 0.00e-00 Homeobox domain
ENSRNOP00000028155 SMART SM00389 IPR001356 137 199 5.20e-26 Homeobox domain
ENSRNOP00000028155 SUPERFAMILY SSF46689 IPR009057 129 196 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSRNOP00000028155 PF00046 4.3e-21 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSRNOP00000028155 GO:0005634 cellular_component nucleus
ENSRNOP00000028155 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSRNOP00000028155 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8364 Xenopus tropicalis 100038094 9823 Sus scrofa 100521411
9555 Papio anubis 101002465 9669 Mustela putorius furo 101690011
7897 Latimeria chalumnae 102366680 7425 Nasonia vitripennis 100116335
7029 Acyrthosiphon pisum 100159676 10224 Saccoglossus kowalevskii 100303529
30195 Bombus terrestris 100648043 8128 Oreochromis niloticus 100709334
132113 Bombus impatiens 100741068 10029 Cricetulus griseus 100772699
7463 Apis florea 100868936 143995 Megachile rotundata 100881540
9305 Sarcophilus harrisii 100925222 30611 Otolemur garnettii 100943700
9597 Pan paniscus 100982957 39432 Saimiri boliviensis 101039504
9685 Felis catus 101090739 9595 Gorilla gorilla 101124584
43179 Ictidomys tridecemlineatus 101976370 8083 Xiphophorus maculatus 102219020
9606 Homo sapiens 1482 7227 Drosophila melanogaster 3355151
9598 Pan troglodytes 462273 9913 Bos taurus 538870
7070 Tribolium castaneum 656094 9544 Macaca mulatta 703795
7460 Apis mellifera 724373 28377 Anolis carolinensis ENSACAG00000003684
9646 Ailuropoda melanoleuca ENSAMEG00000011319 9615 Canis familiaris ENSCAFG00000009469
10141 Cavia porcellus ENSCPOG00000026347 51511 Ciona savignyi ENSCSAVG00000006091
7955 Danio rerio ENSDARG00000018004 9361 Dasypus novemcinctus ENSDNOG00000015890
10020 Dipodomys ordii ENSDORG00000003645 9796 Equus caballus ENSECAG00000023495
69293 Gasterosteus aculeatus ENSGACG00000018433 8049 Gadus morhua ENSGMOG00000015370
9315 Macropus eugenii ENSMEUG00000011672 9103 Meleagris gallopavo ENSMGAG00000003616
30608 Microcebus murinus ENSMICG00000017468 61853 Nomascus leucogenys ENSNLEG00000010047
9258 Ornithorhynchus anatinus ENSOANG00000022656 9986 Oryctolagus cuniculus ENSOCUG00000004296
9978 Ochotona princeps ENSOPRG00000002368 8090 Oryzias latipes ENSORLG00000007346
9601 Pongo abelii ENSPPYG00000016055 13735 Pelodiscus sinensis ENSPSIG00000014981
37347 Tupaia belangeri ENSTBEG00000011031 59729 Taeniopygia guttata ENSTGUG00000009415
31033 Takifugu rubripes ENSTRUG00000010802 10090 Mus musculus 18089
7668 Strongylocentrotus purpuratus 577823 9483 Callithrix jacchus ENSCJAG00000017049
9365 Erinaceus europaeus ENSEEUG00000013947 9371 Echinops telfairi ENSETEG00000000957
9031 Gallus gallus ENSGALG00000002886 9785 Loxodonta africana ENSLAFG00000029311
59463 Myotis lucifugus ENSMLUG00000012413 13616 Monodelphis domestica ENSMODG00000016788
9813 Procavia capensis ENSPCAG00000013736 7757 Petromyzon marinus ENSPMAG00000000997
132908 Pteropus vampyrus ENSPVAG00000003246 42254 Sorex araneus ENSSARG00000002300
99883 Tetraodon nigroviridis ENSTNIG00000017075 9739 Tursiops truncatus ENSTTRG00000004510