Basic Information
Gene ID 12753 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Clock
Full Name Circadian locomoter output cycles protein kaput
Organism Mus musculus [10090]

Cross Reference
UniProt O08785 UniGene Mm.392894
PDB 4F3L OMIM NULL
KEGG mmu:12753 UCSC uc008xuq.1

Protein Interactions
DIP DIP-30958N
IntAct O08785
MINT MINT-4654078
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_031741 Gene3D G3DSA:4.10.280.10 IPR011598 35 87 2.60e-12 Myc-type, basic helix-loop-helix (bHLH) domain
NP_031741 Pfam PF00010 IPR011598 35 83 4.90e-09 Myc-type, basic helix-loop-helix (bHLH) domain
NP_031741 Pfam PF00989 IPR013767 110 176 7.70e-08 PAS fold
NP_031741 PRINTS PR00785 IPR001067 100 123 2.40e-12 Nuclear translocator
NP_031741 PRINTS PR00785 IPR001067 275 292 2.40e-12 Nuclear translocator
NP_031741 PRINTS PR00785 IPR001067 49 64 2.40e-12 Nuclear translocator
NP_031741 ProSiteProfiles PS50112 IPR000014 107 177 0.00e-00 PAS domain
NP_031741 ProSiteProfiles PS50112 IPR000014 285 332 0.00e-00 PAS domain
NP_031741 ProSiteProfiles PS50888 IPR011598 34 84 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
NP_031741 SMART SM00086 IPR001610 336 379 3.00e-09 PAC motif
NP_031741 SMART SM00091 IPR000014 109 175 7.50e-09 PAS domain
NP_031741 SMART SM00091 IPR000014 264 330 1.40e-06 PAS domain
NP_031741 SMART SM00353 IPR011598 40 90 2.60e-14 Myc-type, basic helix-loop-helix (bHLH) domain
NP_031741 SUPERFAMILY SSF47459 IPR011598 31 104 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
NP_031741 SUPERFAMILY SSF55785 IPR000014 118 185 0.00e-00 PAS domain
NP_031741 SUPERFAMILY SSF55785 IPR000014 274 376 0.00e-00 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_031741 PF14598 1.9e-24 PAS_11 PAS domain
NP_031741 PF08447 1.8e-15 PAS_3 PAS fold
NP_031741 PF00989 1.8e-10 PAS PAS fold
NP_031741 PF00010 1.8e-09 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
NP_031741 GO:0006351 biological_process transcription, DNA-templated
NP_031741 GO:0006355 biological_process regulation of transcription, DNA-templated
NP_031741 GO:0006974 biological_process cellular response to DNA damage stimulus
NP_031741 GO:0007165 biological_process signal transduction
NP_031741 GO:0032922 biological_process circadian regulation of gene expression
NP_031741 GO:0048511 biological_process rhythmic process
NP_031741 GO:0005634 cellular_component nucleus
NP_031741 GO:0005667 cellular_component transcription factor complex
NP_031741 GO:0005694 cellular_component chromosome
NP_031741 GO:0005737 cellular_component cytoplasm
NP_031741 GO:0001047 molecular_function core promoter binding
NP_031741 GO:0003677 molecular_function DNA binding
NP_031741 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_031741 GO:0004402 molecular_function histone acetyltransferase activity
NP_031741 GO:0004871 molecular_function signal transducer activity
NP_031741 GO:0046983 molecular_function protein dimerization activity