Basic Information
Gene ID 12916 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Crem
Full Name cAMP-responsive element modulator
Organism Mus musculus [10090]

Cross Reference
UniProt P27699 UniGene Mm.5244
PDB NULL OMIM NULL
KEGG mmu:12916 UCSC uc012ayv.1

Protein Interactions
DIP NULL
IntAct P27699
MINT NULL
STRING NULL

Ensembl/RefSeq
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ENSEMBL
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ENSEMBL
ENSEMBL
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InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000121233 Pfam PF00170 IPR004827 297 353 5.30e-20 Basic-leucine zipper domain
ENSMUSP00000121233 Pfam PF02173 IPR003102 115 153 1.10e-17 Coactivator CBP, pKID
ENSMUSP00000121233 PRINTS PR00041 IPR001630 118 140 4.70e-59 cAMP response element binding (CREB) protein
ENSMUSP00000121233 PRINTS PR00041 IPR001630 167 182 4.70e-59 cAMP response element binding (CREB) protein
ENSMUSP00000121233 PRINTS PR00041 IPR001630 258 269 4.70e-59 cAMP response element binding (CREB) protein
ENSMUSP00000121233 PRINTS PR00041 IPR001630 296 312 4.70e-59 cAMP response element binding (CREB) protein
ENSMUSP00000121233 PRINTS PR00041 IPR001630 314 334 4.70e-59 cAMP response element binding (CREB) protein
ENSMUSP00000121233 PRINTS PR00041 IPR001630 334 351 4.70e-59 cAMP response element binding (CREB) protein
ENSMUSP00000121233 ProSitePatterns PS00036 IPR004827 305 319 - Basic-leucine zipper domain
ENSMUSP00000121233 ProSiteProfiles PS50217 IPR004827 299 350 0.00e-00 Basic-leucine zipper domain
ENSMUSP00000121233 ProSiteProfiles PS50953 IPR003102 101 160 0.00e-00 Coactivator CBP, pKID
ENSMUSP00000121233 SMART SM00338 IPR004827 297 354 9.00e-10 Basic-leucine zipper domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000121233 PF00170 2.8e-20 bZIP_1 bZIP transcription factor
ENSMUSP00000121233 PF02173 4.1e-18 pKID pKID domain
ENSMUSP00000121233 PF07716 2.5e-07 bZIP_2 Basic region leucine zipper

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000121233 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSMUSP00000121233 GO:0005634 cellular_component nucleus
ENSMUSP00000121233 GO:0005667 cellular_component transcription factor complex
ENSMUSP00000121233 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100160473 6087 Hydra magnipapillata 100200223
9601 Pongo abelii 100433182 9823 Sus scrofa 100512363
61853 Nomascus leucogenys 100586647 400682 Amphimedon queenslandica 100638625
30195 Bombus terrestris 100651248 132113 Bombus impatiens 100741354
10029 Cricetulus griseus 100767867 143995 Megachile rotundata 100876424
34638 Metaseiulus occidentalis 100899865 9597 Pan paniscus 100988448
9555 Papio anubis 101010751 39432 Saimiri boliviensis 101037962
7897 Latimeria chalumnae 102356299 7463 Apis florea 100863848
7668 Strongylocentrotus purpuratus 100889197 8083 Xiphophorus maculatus 102221737
13735 Pelodiscus sinensis 102447026 28377 Anolis carolinensis ENSACAG00000000947
9358 Choloepus hoffmanni ENSCHOG00000006471 10141 Cavia porcellus ENSCPOG00000015442
9365 Erinaceus europaeus ENSEEUG00000003158 9685 Felis catus ENSFCAG00000006017
69293 Gasterosteus aculeatus ENSGACG00000014712 9315 Macropus eugenii ENSMEUG00000005351
13616 Monodelphis domestica ENSMODG00000015970 7757 Petromyzon marinus ENSPMAG00000005844
9606 Homo sapiens 1390 7227 Drosophila melanogaster 32817
9031 Gallus gallus 395099 9615 Canis familiaris 403887
7460 Apis mellifera 409401 7955 Danio rerio 573207
7070 Tribolium castaneum 656052 9544 Macaca mulatta 698636
9646 Ailuropoda melanoleuca ENSAMEG00000007902 9913 Bos taurus ENSBTAG00000005474
9483 Callithrix jacchus ENSCJAG00000014066 51511 Ciona savignyi ENSCSAVG00000005696
9361 Dasypus novemcinctus ENSDNOG00000000427 10020 Dipodomys ordii ENSDORG00000001162
9796 Equus caballus ENSECAG00000011220 9371 Echinops telfairi ENSETEG00000004357
9595 Gorilla gorilla ENSGGOG00000003999 8049 Gadus morhua ENSGMOG00000016260
9785 Loxodonta africana ENSLAFG00000000007 9103 Meleagris gallopavo ENSMGAG00000005858
30608 Microcebus murinus ENSMICG00000000835 59463 Myotis lucifugus ENSMLUG00000015031
9669 Mustela putorius furo ENSMPUG00000005982 9258 Ornithorhynchus anatinus ENSOANG00000006077
9986 Oryctolagus cuniculus ENSOCUG00000001657 30611 Otolemur garnettii ENSOGAG00000013986
8128 Oreochromis niloticus ENSONIG00000013380 9978 Ochotona princeps ENSOPRG00000002385
8090 Oryzias latipes ENSORLG00000002359 9813 Procavia capensis ENSPCAG00000010193
132908 Pteropus vampyrus ENSPVAG00000005072 10116 Rattus norvegicus ENSRNOG00000046154
42254 Sorex araneus ENSSARG00000011010 9305 Sarcophilus harrisii ENSSHAG00000017148
43179 Ictidomys tridecemlineatus ENSSTOG00000005403 37347 Tupaia belangeri ENSTBEG00000004847
59729 Taeniopygia guttata ENSTGUG00000000919 99883 Tetraodon nigroviridis ENSTNIG00000008335
31033 Takifugu rubripes ENSTRUG00000007984 9478 Tarsius syrichta ENSTSYG00000012085
9739 Tursiops truncatus ENSTTRG00000015733 30538 Vicugna pacos ENSVPAG00000007496
8364 Xenopus tropicalis ENSXETG00000016392