Basic Information
Gene ID 1385 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name CREB1
Full Name Cyclic AMP-responsive element-binding protein 1
Organism Homo sapiens [9606]

Cross Reference
UniProt P16220 UniGene Hs.516646
PDB 2LXT OMIM 612160
KEGG hsa:1385 UCSC uc002vcc.3

Protein Interactions
DIP DIP-765N
IntAct P16220
MINT MINT-1338714
STRING 9606.ENSP00000387699

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_604391 Pfam PF00170 IPR004827 281 338 4.30e-20 Basic-leucine zipper domain
NP_604391 Pfam PF02173 IPR003102 113 153 4.20e-21 Coactivator CBP, pKID
NP_604391 PRINTS PR00041 IPR001630 118 140 1.50e-62 cAMP response element binding (CREB) protein
NP_604391 PRINTS PR00041 IPR001630 167 182 1.50e-62 cAMP response element binding (CREB) protein
NP_604391 PRINTS PR00041 IPR001630 244 255 1.50e-62 cAMP response element binding (CREB) protein
NP_604391 PRINTS PR00041 IPR001630 280 296 1.50e-62 cAMP response element binding (CREB) protein
NP_604391 PRINTS PR00041 IPR001630 298 318 1.50e-62 cAMP response element binding (CREB) protein
NP_604391 PRINTS PR00041 IPR001630 318 335 1.50e-62 cAMP response element binding (CREB) protein
NP_604391 ProSitePatterns PS00036 IPR004827 289 303 - Basic-leucine zipper domain
NP_604391 ProSiteProfiles PS50217 IPR004827 283 334 0.00e-00 Basic-leucine zipper domain
NP_604391 ProSiteProfiles PS50953 IPR003102 101 160 0.00e-00 Coactivator CBP, pKID
NP_604391 SMART SM00338 IPR004827 281 339 4.10e-09 Basic-leucine zipper domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_604391 PF02173 1.6e-21 pKID pKID domain
NP_604391 PF00170 2e-20 bZIP_1 bZIP transcription factor
NP_604391 PF07716 3e-07 bZIP_2 Basic region leucine zipper

Gene Ontology Annotation
Protein Entry Name Space Description
NP_604391 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
NP_604391 GO:0005634 cellular_component nucleus
NP_604391 GO:0005667 cellular_component transcription factor complex
NP_604391 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity