Basic Information
Gene ID 15375 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Foxa1; Hnf3a, Tcf-3a, Tcf3a
Full Name Hepatocyte nuclear factor 3-alpha
Organism Mus musculus [10090]

Cross Reference
UniProt P35582 UniGene Mm.4578
PDB NULL OMIM NULL
KEGG mmu:15375 UCSC uc007nps.1

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000041118 Gene3D G3DSA:1.10.10.10 IPR011991 164 257 6.30e-42 Winged helix-turn-helix DNA-binding domain
ENSMUSP00000041118 Pfam PF00250 IPR001766 170 265 1.40e-46 Transcription factor, fork head
ENSMUSP00000041118 Pfam PF08430 IPR013638 17 169 5.60e-28 Fork-head N-terminal
ENSMUSP00000041118 Pfam PF09354 IPR018533 393 457 3.00e-19 Forkhead box protein, C-terminal
ENSMUSP00000041118 PRINTS PR00053 IPR001766 170 183 8.00e-25 Transcription factor, fork head
ENSMUSP00000041118 PRINTS PR00053 IPR001766 191 208 8.00e-25 Transcription factor, fork head
ENSMUSP00000041118 PRINTS PR00053 IPR001766 214 231 8.00e-25 Transcription factor, fork head
ENSMUSP00000041118 ProSitePatterns PS00657 IPR018122 170 183 - Transcription factor, fork head, conserved site
ENSMUSP00000041118 ProSitePatterns PS00658 IPR018122 214 220 - Transcription factor, fork head, conserved site
ENSMUSP00000041118 ProSiteProfiles PS50039 IPR001766 170 264 0.00e-00 Transcription factor, fork head
ENSMUSP00000041118 SMART SM00339 IPR001766 168 258 1.30e-64 Transcription factor, fork head

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000041118 PF00250 0 Fork_head Fork head domain
ENSMUSP00000041118 PF08430 5.6e-28 Fork_head_N Forkhead N-terminal region
ENSMUSP00000041118 PF09354 3e-19 HNF_C HNF3 C-terminal domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000041118 GO:0006351 biological_process transcription, DNA-templated
ENSMUSP00000041118 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMUSP00000041118 GO:0005634 cellular_component nucleus
ENSMUSP00000041118 GO:0003677 molecular_function DNA binding
ENSMUSP00000041118 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000041118 GO:0008134 molecular_function transcription factor binding
ENSMUSP00000041118 GO:0019904 molecular_function protein domain specific binding
ENSMUSP00000041118 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9785 Loxodonta africana 100662656 9597 Pan paniscus 100971902
9555 Papio anubis 101003858 39432 Saimiri boliviensis 101042650
43179 Ictidomys tridecemlineatus 101971697 8083 Xiphophorus maculatus 102231744
7897 Latimeria chalumnae 102367282 13735 Pelodiscus sinensis 102462414
9913 Bos taurus 503579 28377 Anolis carolinensis ENSACAG00000001256
9646 Ailuropoda melanoleuca ENSAMEG00000008009 9615 Canis familiaris ENSCAFG00000013743
10141 Cavia porcellus ENSCPOG00000026606 7955 Danio rerio ENSDARG00000019150
9371 Echinops telfairi ENSETEG00000011013 9685 Felis catus ENSFCAG00000028305
9595 Gorilla gorilla ENSGGOG00000022617 9315 Macropus eugenii ENSMEUG00000000643
30608 Microcebus murinus ENSMICG00000003135 13616 Monodelphis domestica ENSMODG00000012030
9669 Mustela putorius furo ENSMPUG00000016255 30611 Otolemur garnettii ENSOGAG00000031319
9978 Ochotona princeps ENSOPRG00000006120 9601 Pongo abelii ENSPPYG00000005758
9598 Pan troglodytes ENSPTRG00000006285 132908 Pteropus vampyrus ENSPVAG00000014588
10116 Rattus norvegicus ENSRNOG00000009284 42254 Sorex araneus ENSSARG00000008208
9305 Sarcophilus harrisii ENSSHAG00000001593 37347 Tupaia belangeri ENSTBEG00000007681
99883 Tetraodon nigroviridis ENSTNIG00000002587 31033 Takifugu rubripes ENSTRUG00000006136
9739 Tursiops truncatus ENSTTRG00000002855 30538 Vicugna pacos ENSVPAG00000009933
8364 Xenopus tropicalis ENSXETG00000025867 59463 Myotis lucifugus ENSMLUG00000029779
9544 Macaca mulatta ENSMMUG00000009653