Basic Information | |||
Gene ID | 1655 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | DDX5; G17P1, HELR, HLR1 | ||
Full Name | Probable ATP-dependent RNA helicase DDX5 | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | P17844 | UniGene | Hs.279806 |
PDB | 4A4D | OMIM | 180630 |
KEGG | hsa:1655 | UCSC | uc002jej.2 |
Protein Interactions | |
DIP | DIP-29844N |
IntAct | P17844 |
MINT | MINT-5000516 |
STRING | 9606.ENSP00000225792 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSP00000462885 | Pfam | PF00270 | IPR011545 | 118 | 288 | 2.40e-41 | DNA/RNA helicase, DEAD/DEAH box type, N-terminal |
ENSP00000462885 | Pfam | PF00271 | IPR001650 | 361 | 435 | 9.20e-26 | Helicase, C-terminal |
ENSP00000462885 | Pfam | PF08061 | IPR012587 | 498 | 532 | 5.40e-19 | P68HR |
ENSP00000462885 | Pfam | PF08061 | IPR012587 | 551 | 583 | 1.30e-16 | P68HR |
ENSP00000462885 | ProSitePatterns | PS00039 | IPR000629 | 246 | 254 | - | RNA helicase, ATP-dependent, DEAD-box, conserved site |
ENSP00000462885 | ProSiteProfiles | PS51192 | IPR014001 | 125 | 300 | 0.00e-00 | Helicase, superfamily 1/2, ATP-binding domain |
ENSP00000462885 | ProSiteProfiles | PS51194 | IPR001650 | 328 | 475 | 0.00e-00 | Helicase, C-terminal |
ENSP00000462885 | ProSiteProfiles | PS51195 | IPR014014 | 94 | 122 | 0.00e-00 | RNA helicase, DEAD-box type, Q motif |
ENSP00000462885 | SMART | SM00487 | IPR014001 | 113 | 316 | 2.60e-66 | Helicase, superfamily 1/2, ATP-binding domain |
ENSP00000462885 | SMART | SM00490 | IPR001650 | 355 | 436 | 1.20e-34 | Helicase, C-terminal |
ENSP00000462885 | SUPERFAMILY | SSF52540 | IPR027417 | 166 | 453 | 0.00e-00 | P-loop containing nucleoside triphosphate hydrolase |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSP00000462885 | PF00270 | 5.89947e-42 | DEAD | DEAD/DEAH box helicase |
ENSP00000462885 | PF08061 | 3.7e-36 | P68HR | P68HR (NUC004) repeat |
ENSP00000462885 | PF00271 | 3e-26 | Helicase_C | Helicase conserved C-terminal domain |
ENSP00000462885 | PF04851 | 0.00062 | ResIII | Type III restriction enzyme, res subunit |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSP00000462885 | GO:0006200 | biological_process | ATP catabolic process |
ENSP00000462885 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSP00000462885 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
ENSP00000462885 | GO:2001014 | biological_process | regulation of skeletal muscle cell differentiation |
ENSP00000462885 | GO:0005634 | cellular_component | nucleus |
ENSP00000462885 | GO:0005730 | cellular_component | nucleolus |
ENSP00000462885 | GO:0003713 | molecular_function | transcription coactivator activity |
ENSP00000462885 | GO:0003723 | molecular_function | RNA binding |
ENSP00000462885 | GO:0003724 | molecular_function | RNA helicase activity |
ENSP00000462885 | GO:0005524 | molecular_function | ATP binding |
ENSP00000462885 | GO:0008026 | molecular_function | ATP-dependent helicase activity |
ENSP00000462885 | GO:0030331 | molecular_function | estrogen receptor binding |