Basic Information
Gene ID 1655 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name DDX5; G17P1, HELR, HLR1
Full Name Probable ATP-dependent RNA helicase DDX5
Organism Homo sapiens [9606]

Cross Reference
UniProt P17844 UniGene Hs.279806
PDB 4A4D OMIM 180630
KEGG hsa:1655 UCSC uc002jej.2

Protein Interactions
DIP DIP-29844N
IntAct P17844
MINT MINT-5000516
STRING 9606.ENSP00000225792

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000462885 Pfam PF00270 IPR011545 118 288 2.40e-41 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
ENSP00000462885 Pfam PF00271 IPR001650 361 435 9.20e-26 Helicase, C-terminal
ENSP00000462885 Pfam PF08061 IPR012587 498 532 5.40e-19 P68HR
ENSP00000462885 Pfam PF08061 IPR012587 551 583 1.30e-16 P68HR
ENSP00000462885 ProSitePatterns PS00039 IPR000629 246 254 - RNA helicase, ATP-dependent, DEAD-box, conserved site
ENSP00000462885 ProSiteProfiles PS51192 IPR014001 125 300 0.00e-00 Helicase, superfamily 1/2, ATP-binding domain
ENSP00000462885 ProSiteProfiles PS51194 IPR001650 328 475 0.00e-00 Helicase, C-terminal
ENSP00000462885 ProSiteProfiles PS51195 IPR014014 94 122 0.00e-00 RNA helicase, DEAD-box type, Q motif
ENSP00000462885 SMART SM00487 IPR014001 113 316 2.60e-66 Helicase, superfamily 1/2, ATP-binding domain
ENSP00000462885 SMART SM00490 IPR001650 355 436 1.20e-34 Helicase, C-terminal
ENSP00000462885 SUPERFAMILY SSF52540 IPR027417 166 453 0.00e-00 P-loop containing nucleoside triphosphate hydrolase

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000462885 PF00270 5.89947e-42 DEAD DEAD/DEAH box helicase
ENSP00000462885 PF08061 3.7e-36 P68HR P68HR (NUC004) repeat
ENSP00000462885 PF00271 3e-26 Helicase_C Helicase conserved C-terminal domain
ENSP00000462885 PF04851 0.00062 ResIII Type III restriction enzyme, res subunit

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000462885 GO:0006200 biological_process ATP catabolic process
ENSP00000462885 GO:0006351 biological_process transcription, DNA-templated
ENSP00000462885 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSP00000462885 GO:2001014 biological_process regulation of skeletal muscle cell differentiation
ENSP00000462885 GO:0005634 cellular_component nucleus
ENSP00000462885 GO:0005730 cellular_component nucleolus
ENSP00000462885 GO:0003713 molecular_function transcription coactivator activity
ENSP00000462885 GO:0003723 molecular_function RNA binding
ENSP00000462885 GO:0003724 molecular_function RNA helicase activity
ENSP00000462885 GO:0005524 molecular_function ATP binding
ENSP00000462885 GO:0008026 molecular_function ATP-dependent helicase activity
ENSP00000462885 GO:0030331 molecular_function estrogen receptor binding