Basic Information | |||
Gene ID | 16800 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | Arhgef2; Kiaa0651, Lbcl1, Lfc | ||
Full Name | Rho guanine nucleotide exchange factor 2 | ||
Organism | Mus musculus [10090] |
Cross Reference | |||
UniProt | Q60875 | UniGene | Mm.482396 |
PDB | NULL | OMIM | NULL |
KEGG | mmu:16800 | UCSC | uc008pwa.1 |
Protein Interactions | |
DIP | NULL |
IntAct | Q60875 |
MINT | MINT-2982807 |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_032513 | Gene3D | G3DSA:1.20.900.10 | IPR000219 | 215 | 450 | 5.80e-49 | Dbl homology (DH) domain |
NP_032513 | Gene3D | G3DSA:2.30.29.30 | IPR011993 | 455 | 587 | 6.60e-45 | Pleckstrin homology-like domain |
NP_032513 | PANTHER | PTHR22825 | IPR015721 | 1 | 983 | 0.00e-00 | Rho GTP exchange factor |
NP_032513 | Pfam | PF00169 | IPR001849 | 475 | 571 | 1.60e-06 | Pleckstrin homology domain |
NP_032513 | Pfam | PF00621 | IPR000219 | 240 | 432 | 1.60e-33 | Dbl homology (DH) domain |
NP_032513 | ProSitePatterns | PS00479 | IPR002219 | 40 | 86 | - | Protein kinase C-like, phorbol ester/diacylglycerol binding |
NP_032513 | ProSiteProfiles | PS50003 | IPR001849 | 473 | 572 | 0.00e-00 | Pleckstrin homology domain |
NP_032513 | ProSiteProfiles | PS50010 | IPR000219 | 236 | 433 | 0.00e-00 | Dbl homology (DH) domain |
NP_032513 | ProSiteProfiles | PS50081 | IPR002219 | 39 | 86 | 0.00e-00 | Protein kinase C-like, phorbol ester/diacylglycerol binding |
NP_032513 | SMART | SM00109 | IPR002219 | 40 | 86 | 1.70e-11 | Protein kinase C-like, phorbol ester/diacylglycerol binding |
NP_032513 | SMART | SM00233 | IPR001849 | 474 | 574 | 3.30e-13 | Pleckstrin homology domain |
NP_032513 | SMART | SM00325 | IPR000219 | 240 | 432 | 9.60e-61 | Dbl homology (DH) domain |
NP_032513 | SUPERFAMILY | SSF48065 | IPR000219 | 216 | 452 | 0.00e-00 | Dbl homology (DH) domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_032513 | PF00621 | 6.3e-34 | RhoGEF | RhoGEF domain |
NP_032513 | PF00169 | 5.9e-07 | PH | PH domain |
NP_032513 | PF00130 | 8.3e-06 | C1_1 | Phorbol esters/diacylglycerol binding domain (C1 domain) |
NP_032513 | PF14446 | 0.00023 | Prok-RING_1 | Prokaryotic RING finger family 1 |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_032513 | GO:0005737 | cellular_component | cytoplasm |
NP_032513 | GO:0005089 | molecular_function | Rho guanyl-nucleotide exchange factor activity |