Basic Information
Gene ID 16800 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Arhgef2; Kiaa0651, Lbcl1, Lfc
Full Name Rho guanine nucleotide exchange factor 2
Organism Mus musculus [10090]

Cross Reference
UniProt Q60875 UniGene Mm.482396
PDB NULL OMIM NULL
KEGG mmu:16800 UCSC uc008pwa.1

Protein Interactions
DIP NULL
IntAct Q60875
MINT MINT-2982807
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_032513 Gene3D G3DSA:1.20.900.10 IPR000219 215 450 5.80e-49 Dbl homology (DH) domain
NP_032513 Gene3D G3DSA:2.30.29.30 IPR011993 455 587 6.60e-45 Pleckstrin homology-like domain
NP_032513 PANTHER PTHR22825 IPR015721 1 983 0.00e-00 Rho GTP exchange factor
NP_032513 Pfam PF00169 IPR001849 475 571 1.60e-06 Pleckstrin homology domain
NP_032513 Pfam PF00621 IPR000219 240 432 1.60e-33 Dbl homology (DH) domain
NP_032513 ProSitePatterns PS00479 IPR002219 40 86 - Protein kinase C-like, phorbol ester/diacylglycerol binding
NP_032513 ProSiteProfiles PS50003 IPR001849 473 572 0.00e-00 Pleckstrin homology domain
NP_032513 ProSiteProfiles PS50010 IPR000219 236 433 0.00e-00 Dbl homology (DH) domain
NP_032513 ProSiteProfiles PS50081 IPR002219 39 86 0.00e-00 Protein kinase C-like, phorbol ester/diacylglycerol binding
NP_032513 SMART SM00109 IPR002219 40 86 1.70e-11 Protein kinase C-like, phorbol ester/diacylglycerol binding
NP_032513 SMART SM00233 IPR001849 474 574 3.30e-13 Pleckstrin homology domain
NP_032513 SMART SM00325 IPR000219 240 432 9.60e-61 Dbl homology (DH) domain
NP_032513 SUPERFAMILY SSF48065 IPR000219 216 452 0.00e-00 Dbl homology (DH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_032513 PF00621 6.3e-34 RhoGEF RhoGEF domain
NP_032513 PF00169 5.9e-07 PH PH domain
NP_032513 PF00130 8.3e-06 C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain)
NP_032513 PF14446 0.00023 Prok-RING_1 Prokaryotic RING finger family 1

Gene Ontology Annotation
Protein Entry Name Space Description
NP_032513 GO:0005737 cellular_component cytoplasm
NP_032513 GO:0005089 molecular_function Rho guanyl-nucleotide exchange factor activity