Basic Information
Gene ID 16842 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Lef1; Lef-1
Full Name Lymphoid enhancer-binding factor 1
Organism Mus musculus [10090]

Cross Reference
UniProt P27782 UniGene Mm.255219
PDB 3OUX OMIM NULL
KEGG mmu:16842 UCSC uc008rjf.1

Protein Interactions
DIP DIP-35132N
IntAct P27782
MINT MINT-8177749
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_034833 Gene3D G3DSA:1.10.30.10 IPR009071 295 377 8.20e-29 High mobility group box domain
NP_034833 Gene3D G3DSA:4.10.900.10 IPR027397 1 67 2.30e-26 Catenin binding domain
NP_034833 PANTHER PTHR10373 IPR024940 1 397 0.00e-00 Transcription factor TCF/LEF
NP_034833 PANTHER PTHR10373:SF11 IPR028769 1 397 0.00e-00 Lymphoid enhancer-binding factor 1
NP_034833 Pfam PF00505 IPR009071 297 364 1.20e-21 High mobility group box domain
NP_034833 Pfam PF08347 IPR013558 1 211 1.00e-72 CTNNB1 binding, N-teminal
NP_034833 ProSiteProfiles PS50118 IPR009071 297 365 0.00e-00 High mobility group box domain
NP_034833 SMART SM00398 IPR009071 296 366 2.50e-25 High mobility group box domain
NP_034833 SUPERFAMILY SSF47095 IPR009071 296 377 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_034833 PF08347 0 CTNNB1_binding N-terminal CTNNB1 binding
NP_034833 PF00505 1.2e-21 HMG_box HMG (high mobility group) box
NP_034833 PF09011 2.6e-08 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
NP_034833 GO:0060070 biological_process canonical Wnt signaling pathway
NP_034833 GO:0005634 cellular_component nucleus
NP_034833 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_034833 GO:0008013 molecular_function beta-catenin binding