Basic Information
Gene ID 17126 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Smad2; Madh2, Madr2
Full Name Mothers against decapentaplegic homolog 2
Organism Mus musculus [10090]

Cross Reference
UniProt Q62432 UniGene Mm.490934
PDB NULL OMIM NULL
KEGG mmu:17126 UCSC uc008fqo.2

Protein Interactions
DIP NULL
IntAct Q62432
MINT MINT-99148
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_034884 Gene3D G3DSA:2.60.200.10 IPR017855 266 467 7.90e-100 SMAD domain-like
NP_034884 Gene3D G3DSA:3.90.520.10 IPR013019 2 183 3.80e-59 MAD homology, MH1
NP_034884 PANTHER PTHR13703 IPR013790 1 467 0.00e-00 Dwarfin
NP_034884 Pfam PF03165 IPR003619 41 171 6.90e-43 MAD homology 1, Dwarfin-type
NP_034884 Pfam PF03166 IPR001132 269 444 1.50e-77 SMAD domain, Dwarfin-type
NP_034884 ProSiteProfiles PS51075 IPR013019 10 176 0.00e-00 MAD homology, MH1
NP_034884 ProSiteProfiles PS51076 IPR001132 274 467 0.00e-00 SMAD domain, Dwarfin-type
NP_034884 SMART SM00523 IPR003619 36 174 2.10e-67 MAD homology 1, Dwarfin-type
NP_034884 SMART SM00524 IPR001132 272 443 4.60e-111 SMAD domain, Dwarfin-type
NP_034884 SUPERFAMILY SSF49879 IPR008984 217 458 0.00e-00 SMAD/FHA domain
NP_034884 SUPERFAMILY SSF56366 IPR013019 111 171 0.00e-00 MAD homology, MH1
NP_034884 SUPERFAMILY SSF56366 IPR013019 31 80 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_034884 PF03166 0 MH2 MH2 domain
NP_034884 PF03165 3.79752e-43 MH1 MH1 domain
NP_034884 PF10401 2.4e-05 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
NP_034884 GO:0006351 biological_process transcription, DNA-templated
NP_034884 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
NP_034884 GO:0005634 cellular_component nucleus
NP_034884 GO:0005667 cellular_component transcription factor complex
NP_034884 GO:0005737 cellular_component cytoplasm
NP_034884 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity