Basic Information
Gene ID 17127 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Smad3; Madh3
Full Name Mothers against decapentaplegic homolog 3
Organism Mus musculus [10090]

Cross Reference
UniProt Q8BUN5 UniGene Mm.7320
PDB NULL OMIM NULL
KEGG mmu:17127 UCSC uc009qbi.1

Protein Interactions
DIP DIP-29717N
IntAct Q8BUN5
MINT MINT-262056
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_058049 Gene3D G3DSA:2.60.200.10 IPR017855 224 425 8.10e-99 SMAD domain-like
NP_058049 Gene3D G3DSA:3.90.520.10 IPR013019 2 143 1.10e-64 MAD homology, MH1
NP_058049 PANTHER PTHR13703 IPR013790 1 425 0.00e-00 Dwarfin
NP_058049 Pfam PF03165 IPR003619 31 131 1.20e-43 MAD homology 1, Dwarfin-type
NP_058049 Pfam PF03166 IPR001132 227 402 2.20e-77 SMAD domain, Dwarfin-type
NP_058049 ProSiteProfiles PS51075 IPR013019 10 136 0.00e-00 MAD homology, MH1
NP_058049 ProSiteProfiles PS51076 IPR001132 232 425 0.00e-00 SMAD domain, Dwarfin-type
NP_058049 SMART SM00523 IPR003619 26 134 1.10e-70 MAD homology 1, Dwarfin-type
NP_058049 SMART SM00524 IPR001132 230 401 1.40e-111 SMAD domain, Dwarfin-type
NP_058049 SUPERFAMILY SSF49879 IPR008984 176 416 0.00e-00 SMAD/FHA domain
NP_058049 SUPERFAMILY SSF56366 IPR013019 10 131 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_058049 PF03166 0 MH2 MH2 domain
NP_058049 PF03165 6.16571e-44 MH1 MH1 domain
NP_058049 PF10401 6.5e-05 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
NP_058049 GO:0006351 biological_process transcription, DNA-templated
NP_058049 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
NP_058049 GO:0005634 cellular_component nucleus
NP_058049 GO:0005667 cellular_component transcription factor complex
NP_058049 GO:0005737 cellular_component cytoplasm
NP_058049 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity