Basic Information | |||
Gene ID | 172789 | ||
Gene Name | irx-1; C36F7.1 | ||
Full Name | Putative iroquois-class homeodomain protein irx-1 | ||
Organism | Caenorhabditis elegans [6239] |
Cross Reference | |||
UniProt | Q93348 | UniGene | Cel.6806 |
PDB | NULL | OMIM | NULL |
KEGG | cel:CELE_C36F7.1 | UCSC | C36F7.1 |
Protein Interactions | |
DIP | NULL |
IntAct | Q93348 |
MINT | NULL |
STRING | 6239.C36F7.1 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
C36F7.1 | Gene3D | G3DSA:1.10.10.60 | IPR009057 | 118 | 188 | 3.10e-25 | Homeodomain-like |
C36F7.1 | Pfam | PF05920 | IPR008422 | 133 | 172 | 5.90e-15 | Homeobox KN domain |
C36F7.1 | ProSitePatterns | PS00027 | IPR017970 | 151 | 174 | - | Homeobox, conserved site |
C36F7.1 | ProSiteProfiles | PS50071 | IPR001356 | 118 | 176 | 0.00e-00 | Homeobox domain |
C36F7.1 | SMART | SM00389 | IPR001356 | 116 | 180 | 2.30e-14 | Homeobox domain |
C36F7.1 | SMART | SM00548 | IPR003893 | 259 | 276 | 3.30e-08 | Iroquois-class homeodomain protein |
C36F7.1 | SUPERFAMILY | SSF46689 | IPR009057 | 119 | 184 | 0.00e-00 | Homeodomain-like |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
C36F7.1 | PF05920 | 2.6e-15 | Homeobox_KN | Homeobox KN domain |
C36F7.1 | PF00046 | 1.2e-07 | Homeobox | Homeobox domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
C36F7.1 | GO:0000122 | biological_process | negative regulation of transcription from RNA polymerase II promoter |
C36F7.1 | GO:0006351 | biological_process | transcription, DNA-templated |
C36F7.1 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
C36F7.1 | GO:0007275 | biological_process | multicellular organismal development |
C36F7.1 | GO:0007399 | biological_process | nervous system development |
C36F7.1 | GO:0007420 | biological_process | brain development |
C36F7.1 | GO:0009953 | biological_process | dorsal/ventral pattern formation |
C36F7.1 | GO:0009954 | biological_process | proximal/distal pattern formation |
C36F7.1 | GO:0030154 | biological_process | cell differentiation |
C36F7.1 | GO:0045665 | biological_process | negative regulation of neuron differentiation |
C36F7.1 | GO:0045666 | biological_process | positive regulation of neuron differentiation |
C36F7.1 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
C36F7.1 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
C36F7.1 | GO:0005634 | cellular_component | nucleus |
C36F7.1 | GO:0003677 | molecular_function | DNA binding |
C36F7.1 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
C36F7.1 | GO:0043565 | molecular_function | sequence-specific DNA binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
7425 | Nasonia vitripennis | 100121331 | 6087 | Hydra magnipapillata | 100211771 |
10224 | Saccoglossus kowalevskii | 100302711 | 9601 | Pongo abelii | 100445153 |
30195 | Bombus terrestris | 100649960 | 9597 | Pan paniscus | 100980714 |
39432 | Saimiri boliviensis | 101041270 | 31033 | Takifugu rubripes | 101067172 |
9606 | Homo sapiens | 153572 | 8364 | Xenopus tropicalis | 100038201 |
7029 | Acyrthosiphon pisum | 100165521 | 132113 | Bombus impatiens | 100743699 |
10029 | Cricetulus griseus | 100773873 | 7463 | Apis florea | 100863047 |
143995 | Megachile rotundata | 100877027 | 34638 | Metaseiulus occidentalis | 100903651 |
9555 | Papio anubis | 101011651 | 9595 | Gorilla gorilla | 101144938 |
8083 | Xiphophorus maculatus | 102227918 | 7897 | Latimeria chalumnae | 102364368 |
13735 | Pelodiscus sinensis | 102451318 | 7460 | Apis mellifera | 412839 |
9615 | Canis familiaris | 487276 | 7668 | Strongylocentrotus purpuratus | 590306 |
9544 | Macaca mulatta | 698232 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000013363 |
7719 | Ciona intestinalis | ENSCING00000006449 | 7955 | Danio rerio | ENSDARG00000036051 |
9361 | Dasypus novemcinctus | ENSDNOG00000002196 | 13616 | Monodelphis domestica | ENSMODG00000013202 |
9978 | Ochotona princeps | ENSOPRG00000012917 | 8090 | Oryzias latipes | ENSORLG00000013711 |
7757 | Petromyzon marinus | ENSPMAG00000002391 | 37347 | Tupaia belangeri | ENSTBEG00000008254 |
9478 | Tarsius syrichta | ENSTSYG00000006383 | 7227 | Drosophila melanogaster | 39441 |
9598 | Pan troglodytes | 454093 | 10090 | Mus musculus | 64379 |
7070 | Tribolium castaneum | 660345 | 28377 | Anolis carolinensis | ENSACAG00000000694 |
9913 | Bos taurus | ENSBTAG00000047499 | 9483 | Callithrix jacchus | ENSCJAG00000008516 |
10141 | Cavia porcellus | ENSCPOG00000011984 | 51511 | Ciona savignyi | ENSCSAVG00000005021 |
10020 | Dipodomys ordii | ENSDORG00000012265 | 9796 | Equus caballus | ENSECAG00000023545 |
9365 | Erinaceus europaeus | ENSEEUG00000015645 | 9371 | Echinops telfairi | ENSETEG00000020207 |
9685 | Felis catus | ENSFCAG00000023076 | 69293 | Gasterosteus aculeatus | ENSGACG00000016681 |
9031 | Gallus gallus | ENSGALG00000023738 | 8049 | Gadus morhua | ENSGMOG00000004163 |
9785 | Loxodonta africana | ENSLAFG00000000090 | 9315 | Macropus eugenii | ENSMEUG00000008376 |
9103 | Meleagris gallopavo | ENSMGAG00000007217 | 30608 | Microcebus murinus | ENSMICG00000002308 |
59463 | Myotis lucifugus | ENSMLUG00000002364 | 9669 | Mustela putorius furo | ENSMPUG00000003373 |
61853 | Nomascus leucogenys | ENSNLEG00000001193 | 9258 | Ornithorhynchus anatinus | ENSOANG00000001748 |
9986 | Oryctolagus cuniculus | ENSOCUG00000009172 | 30611 | Otolemur garnettii | ENSOGAG00000012910 |
8128 | Oreochromis niloticus | ENSONIG00000002803 | 9813 | Procavia capensis | ENSPCAG00000007992 |
132908 | Pteropus vampyrus | ENSPVAG00000001273 | 10116 | Rattus norvegicus | ENSRNOG00000011180 |
42254 | Sorex araneus | ENSSARG00000009535 | 9305 | Sarcophilus harrisii | ENSSHAG00000006589 |
9823 | Sus scrofa | ENSSSCG00000002830 | 43179 | Ictidomys tridecemlineatus | ENSSTOG00000023408 |
59729 | Taeniopygia guttata | ENSTGUG00000008517 | 99883 | Tetraodon nigroviridis | ENSTNIG00000013613 |
9739 | Tursiops truncatus | ENSTTRG00000006214 |