Basic Information
Gene ID 172981
Gene Name daf-16; R13H8.1
Full Name Forkhead box protein O
Organism Caenorhabditis elegans [6239]

Cross Reference
UniProt O16850 UniGene Cel.18378
PDB NULL OMIM NULL
KEGG cel:CELE_R13H8.1 UCSC R13H8.1c

Protein Interactions
DIP DIP-25581N
IntAct O16850
MINT MINT-1069794
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
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REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
R13H8.1h Gene3D G3DSA:1.10.10.10 IPR011991 167 256 1.90e-41 Winged helix-turn-helix DNA-binding domain
R13H8.1h Pfam PF00250 IPR001766 178 263 8.90e-22 Transcription factor, fork head
R13H8.1h PRINTS PR00053 IPR001766 175 188 5.30e-12 Transcription factor, fork head
R13H8.1h PRINTS PR00053 IPR001766 196 213 5.30e-12 Transcription factor, fork head
R13H8.1h PRINTS PR00053 IPR001766 224 241 5.30e-12 Transcription factor, fork head
R13H8.1h ProSitePatterns PS00658 IPR018122 224 230 - Transcription factor, fork head, conserved site
R13H8.1h ProSiteProfiles PS50039 IPR001766 175 268 0.00e-00 Transcription factor, fork head
R13H8.1h SMART SM00339 IPR001766 173 262 3.70e-45 Transcription factor, fork head

Pfam Annotation
Protein Pfam ID E.value Name Description
R13H8.1h PF00250 3.7e-22 Fork_head Fork head domain

Gene Ontology Annotation
Protein Entry Name Space Description
R13H8.1h GO:0006351 biological_process transcription, DNA-templated
R13H8.1h GO:0006355 biological_process regulation of transcription, DNA-templated
R13H8.1h GO:0007049 biological_process cell cycle
R13H8.1h GO:0007275 biological_process multicellular organismal development
R13H8.1h GO:0008285 biological_process negative regulation of cell proliferation
R13H8.1h GO:0010259 biological_process multicellular organismal aging
R13H8.1h GO:0019216 biological_process regulation of lipid metabolic process
R13H8.1h GO:0030154 biological_process cell differentiation
R13H8.1h GO:0030308 biological_process negative regulation of cell growth
R13H8.1h GO:0040008 biological_process regulation of growth
R13H8.1h GO:0042593 biological_process glucose homeostasis
R13H8.1h GO:0046627 biological_process negative regulation of insulin receptor signaling pathway
R13H8.1h GO:0005634 cellular_component nucleus
R13H8.1h GO:0005737 cellular_component cytoplasm
R13H8.1h GO:0003677 molecular_function DNA binding
R13H8.1h GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
R13H8.1h GO:0043565 molecular_function sequence-specific DNA binding