Basic Information
Gene ID 176360
Gene Name hlh-11; F58A4.7
Full Name Helix-loop-helix protein 11
Organism Caenorhabditis elegans [6239]

Cross Reference
UniProt P34474 UniGene Cel.17799
PDB NULL OMIM NULL
KEGG cel:CELE_F58A4.7 UCSC F58A4.7a.1

Protein Interactions
DIP NULL
IntAct P34474
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
F58A4.7b.2 Gene3D G3DSA:4.10.280.10 IPR011598 109 161 2.80e-11 Myc-type, basic helix-loop-helix (bHLH) domain
F58A4.7b.2 Pfam PF00010 IPR011598 113 163 5.70e-13 Myc-type, basic helix-loop-helix (bHLH) domain
F58A4.7b.2 ProSiteProfiles PS50888 IPR011598 112 163 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
F58A4.7b.2 SMART SM00353 IPR011598 118 169 2.30e-15 Myc-type, basic helix-loop-helix (bHLH) domain
F58A4.7b.2 SUPERFAMILY SSF47459 IPR011598 107 166 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
F58A4.7b.2 PF00010 3.4e-13 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
F58A4.7b.2 GO:0006366 biological_process transcription from RNA polymerase II promoter
F58A4.7b.2 GO:0006461 biological_process protein complex assembly
F58A4.7b.2 GO:0006978 biological_process DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
F58A4.7b.2 GO:0008285 biological_process negative regulation of cell proliferation
F58A4.7b.2 GO:0043065 biological_process positive regulation of apoptotic process
F58A4.7b.2 GO:0043066 biological_process negative regulation of apoptotic process
F58A4.7b.2 GO:0043392 biological_process negative regulation of DNA binding
F58A4.7b.2 GO:0043922 biological_process negative regulation by host of viral transcription
F58A4.7b.2 GO:0043923 biological_process positive regulation by host of viral transcription
F58A4.7b.2 GO:0045736 biological_process negative regulation of cyclin-dependent protein serine/threonine kinase activity
F58A4.7b.2 GO:0045892 biological_process negative regulation of transcription, DNA-templated
F58A4.7b.2 GO:0045893 biological_process positive regulation of transcription, DNA-templated
F58A4.7b.2 GO:0071157 biological_process negative regulation of cell cycle arrest
F58A4.7b.2 GO:0071549 biological_process cellular response to dexamethasone stimulus
F58A4.7b.2 GO:2001269 biological_process positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
F58A4.7b.2 GO:0005634 cellular_component nucleus
F58A4.7b.2 GO:0017053 cellular_component transcriptional repressor complex
F58A4.7b.2 GO:0000978 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding
F58A4.7b.2 GO:0001077 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
F58A4.7b.2 GO:0003677 molecular_function DNA binding
F58A4.7b.2 GO:0003705 molecular_function RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
F58A4.7b.2 GO:0003713 molecular_function transcription coactivator activity
F58A4.7b.2 GO:0005515 molecular_function protein binding
F58A4.7b.2 GO:0042803 molecular_function protein homodimerization activity
F58A4.7b.2 GO:0042826 molecular_function histone deacetylase binding
F58A4.7b.2 GO:0043565 molecular_function sequence-specific DNA binding
F58A4.7b.2 GO:0044212 molecular_function transcription regulatory region DNA binding
F58A4.7b.2 GO:0046982 molecular_function protein heterodimerization activity
F58A4.7b.2 GO:0070888 molecular_function E-box binding