Basic Information
Gene ID 18072 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Nhlh2; Hen2
Full Name Helix-loop-helix protein 2
Organism Mus musculus [10090]

Cross Reference
UniProt Q64221 UniGene Mm.137286
PDB NULL OMIM NULL
KEGG mmu:18072 UCSC uc008qro.2

Protein Interactions
DIP NULL
IntAct Q64221
MINT NULL
STRING 10090.ENSMUSP00000064355

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000064355 Gene3D G3DSA:4.10.280.10 IPR011598 71 134 7.50e-21 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMUSP00000064355 Pfam PF00010 IPR011598 79 129 1.10e-18 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMUSP00000064355 ProSiteProfiles PS50888 IPR011598 77 129 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMUSP00000064355 SMART SM00353 IPR011598 83 135 2.70e-19 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMUSP00000064355 SUPERFAMILY SSF47459 IPR011598 77 134 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000064355 PF00010 1.1e-18 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000064355 GO:0006351 biological_process transcription, DNA-templated
ENSMUSP00000064355 GO:0005634 cellular_component nucleus
ENSMUSP00000064355 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100058552 7425 Nasonia vitripennis 100122259
7029 Acyrthosiphon pisum 100166107 9601 Pongo abelii 100434968
9823 Sus scrofa 100512227 61853 Nomascus leucogenys 100591267
30195 Bombus terrestris 100644528 9785 Loxodonta africana 100661144
8128 Oreochromis niloticus 100691335 10141 Cavia porcellus 100723052
132113 Bombus impatiens 100740753 10029 Cricetulus griseus 100761552
7463 Apis florea 100871681 7668 Strongylocentrotus purpuratus 100890854
30611 Otolemur garnettii 100950845 9597 Pan paniscus 100994413
9555 Papio anubis 101000891 9595 Gorilla gorilla 101152442
9669 Mustela putorius furo 101692215 8083 Xiphophorus maculatus 102232923
7897 Latimeria chalumnae 102354796 59463 Myotis lucifugus 102419785
143995 Megachile rotundata 100879325 9305 Sarcophilus harrisii 100927527
39432 Saimiri boliviensis 101049184 31033 Takifugu rubripes 101069975
43179 Ictidomys tridecemlineatus 101954474 9606 Homo sapiens 4807
9646 Ailuropoda melanoleuca ENSAMEG00000010851 9483 Callithrix jacchus ENSCJAG00000012807
9103 Meleagris gallopavo ENSMGAG00000016096 9739 Tursiops truncatus ENSTTRG00000003112
6239 Caenorhabditis elegans 183427 10116 Rattus norvegicus 289230
7227 Drosophila melanogaster 31397 9615 Canis familiaris 483135
9913 Bos taurus 525699 28377 Anolis carolinensis ENSACAG00000010649
9361 Dasypus novemcinctus ENSDNOG00000008961 9371 Echinops telfairi ENSETEG00000009677
9685 Felis catus ENSFCAG00000028313 69293 Gasterosteus aculeatus ENSGACG00000014053
9031 Gallus gallus ENSGALG00000025817 8049 Gadus morhua ENSGMOG00000020309
9315 Macropus eugenii ENSMEUG00000003022 30608 Microcebus murinus ENSMICG00000002851
9986 Oryctolagus cuniculus ENSOCUG00000015744 9978 Ochotona princeps ENSOPRG00000006661
9813 Procavia capensis ENSPCAG00000009061 132908 Pteropus vampyrus ENSPVAG00000012688
59729 Taeniopygia guttata ENSTGUG00000013389 99883 Tetraodon nigroviridis ENSTNIG00000010331
9478 Tarsius syrichta ENSTSYG00000000582 8364 Xenopus tropicalis ENSXETG00000005841