Basic Information
Gene ID 18171 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Nr1i2; Pxr
Full Name Nuclear receptor subfamily 1 group I member 2
Organism Mus musculus [10090]

Cross Reference
UniProt O54915 UniGene Mm.8509
PDB NULL OMIM NULL
KEGG mmu:18171 UCSC uc007zeq.1

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000023504 Gene3D G3DSA:1.10.565.10 IPR008946 203 427 6.80e-64 Nuclear hormone receptor, ligand-binding
ENSMUSP00000023504 Gene3D G3DSA:1.10.565.10 IPR008946 93 123 6.80e-64 Nuclear hormone receptor, ligand-binding
ENSMUSP00000023504 Gene3D G3DSA:3.30.50.10 IPR013088 38 92 4.20e-23 Zinc finger, NHR/GATA-type
ENSMUSP00000023504 Pfam PF00104 IPR000536 237 407 5.10e-19 Nuclear hormone receptor, ligand-binding, core
ENSMUSP00000023504 Pfam PF00105 IPR001628 37 106 5.10e-27 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000023504 PRINTS PR00047 IPR001628 38 54 1.30e-17 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000023504 PRINTS PR00047 IPR001628 54 69 1.30e-17 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000023504 PRINTS PR00047 IPR001628 88 96 1.30e-17 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000023504 PRINTS PR00047 IPR001628 96 104 1.30e-17 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000023504 PRINTS PR00398 IPR001723 100 110 6.20e-20 Steroid hormone receptor
ENSMUSP00000023504 PRINTS PR00398 IPR001723 243 264 6.20e-20 Steroid hormone receptor
ENSMUSP00000023504 PRINTS PR00398 IPR001723 264 280 6.20e-20 Steroid hormone receptor
ENSMUSP00000023504 PRINTS PR00398 IPR001723 330 345 6.20e-20 Steroid hormone receptor
ENSMUSP00000023504 PRINTS PR00398 IPR001723 389 406 6.20e-20 Steroid hormone receptor
ENSMUSP00000023504 ProSitePatterns PS00031 IPR001628 38 64 - Zinc finger, nuclear hormone receptor-type
ENSMUSP00000023504 ProSiteProfiles PS51030 IPR001628 35 111 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000023504 SMART SM00399 IPR001628 35 107 2.00e-35 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000023504 SMART SM00430 IPR000536 242 401 1.50e-37 Nuclear hormone receptor, ligand-binding, core
ENSMUSP00000023504 SUPERFAMILY SSF48508 IPR008946 140 427 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000023504 PF00105 2.4e-27 zf-C4 Zinc finger, C4 type (two domains)
ENSMUSP00000023504 PF00104 5.1e-19 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000023504 GO:0006351 biological_process transcription, DNA-templated
ENSMUSP00000023504 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMUSP00000023504 GO:0043401 biological_process steroid hormone mediated signaling pathway
ENSMUSP00000023504 GO:0005634 cellular_component nucleus
ENSMUSP00000023504 GO:0003677 molecular_function DNA binding
ENSMUSP00000023504 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000023504 GO:0003707 molecular_function steroid hormone receptor activity
ENSMUSP00000023504 GO:0008270 molecular_function zinc ion binding
ENSMUSP00000023504 GO:0043565 molecular_function sequence-specific DNA binding
ENSMUSP00000023504 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9986 Oryctolagus cuniculus 100008739 8128 Oreochromis niloticus 100534472
9597 Pan paniscus 100971952 9555 Papio anubis 101024860
39432 Saimiri boliviensis 101051844 9595 Gorilla gorilla 101124311
9913 Bos taurus 493713 8083 Xiphophorus maculatus ENSXMAG00000003990
9598 Pan troglodytes 745458 9646 Ailuropoda melanoleuca ENSAMEG00000007006
9615 Canis familiaris ENSCAFG00000011094 9483 Callithrix jacchus ENSCJAG00000008854
10141 Cavia porcellus ENSCPOG00000020161 10020 Dipodomys ordii ENSDORG00000003966
9796 Equus caballus ENSECAG00000008728 9365 Erinaceus europaeus ENSEEUG00000004541
9371 Echinops telfairi ENSETEG00000018117 9685 Felis catus ENSFCAG00000006092
7897 Latimeria chalumnae ENSLACG00000010334 9785 Loxodonta africana ENSLAFG00000007829
9315 Macropus eugenii ENSMEUG00000000113 30608 Microcebus murinus ENSMICG00000008054
59463 Myotis lucifugus ENSMLUG00000002877 9544 Macaca mulatta ENSMMUG00000001976
13616 Monodelphis domestica ENSMODG00000018212 9669 Mustela putorius furo ENSMPUG00000008376
61853 Nomascus leucogenys ENSNLEG00000005060 30611 Otolemur garnettii ENSOGAG00000006017
9978 Ochotona princeps ENSOPRG00000010448 8090 Oryzias latipes ENSORLG00000017953
9601 Pongo abelii ENSPPYG00000013508 13735 Pelodiscus sinensis ENSPSIG00000004437
132908 Pteropus vampyrus ENSPVAG00000000884 9305 Sarcophilus harrisii ENSSHAG00000004437
9823 Sus scrofa ENSSSCG00000011890 43179 Ictidomys tridecemlineatus ENSSTOG00000014988
99883 Tetraodon nigroviridis ENSTNIG00000013932 31033 Takifugu rubripes ENSTRUG00000003245
9478 Tarsius syrichta ENSTSYG00000010757 9739 Tursiops truncatus ENSTTRG00000016650
30538 Vicugna pacos ENSVPAG00000009309 8364 Xenopus tropicalis ENSXETG00000018029