Basic Information
Gene ID 1870 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name E2F2
Full Name Transcription factor E2F2
Organism Homo sapiens [9606]

Cross Reference
UniProt Q14209 UniGene Hs.194333
PDB 1N4M OMIM 600426
KEGG hsa:1870 UCSC uc001bhe.2

Protein Interactions
DIP DIP-258N
IntAct Q14209
MINT MINT-249663
STRING 9606.ENSP00000355249

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000355249 Gene3D G3DSA:1.10.10.10 IPR011991 126 195 9.60e-28 Winged helix-turn-helix DNA-binding domain
ENSP00000355249 PANTHER PTHR12081 IPR015633 7 437 0.00e-00 E2F Family
ENSP00000355249 Pfam PF02319 IPR003316 129 194 6.00e-24 Transcription factor E2F/dimerisation partner (TDP)

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000355249 PF02319 3.3e-24 E2F_TDP E2F/DP family winged-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000355249 GO:0005667 cellular_component transcription factor complex
ENSP00000355249 GO:0003677 molecular_function DNA binding
ENSP00000355249 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100163786 6087 Hydra magnipapillata 100201375
9483 Callithrix jacchus 100414776 8128 Oreochromis niloticus 100691560
9597 Pan paniscus 100984393 39432 Saimiri boliviensis 101042612
9669 Mustela putorius furo 101678713 61853 Nomascus leucogenys 100583853
9555 Papio anubis 101015623 9685 Felis catus 101098067
9796 Equus caballus ENSECAG00000023922 9365 Erinaceus europaeus ENSEEUG00000013383
8049 Gadus morhua ENSGMOG00000002446 9315 Macropus eugenii ENSMEUG00000005057
9103 Meleagris gallopavo ENSMGAG00000001492 132908 Pteropus vampyrus ENSPVAG00000008827
59729 Taeniopygia guttata ENSTGUG00000000907 8083 Xiphophorus maculatus ENSXMAG00000012568
9598 Pan troglodytes 469153 7955 Danio rerio 568846
7070 Tribolium castaneum 656396 9544 Macaca mulatta 710200
28377 Anolis carolinensis ENSACAG00000013716 9913 Bos taurus ENSBTAG00000014400
9615 Canis familiaris ENSCAFG00000013273 10141 Cavia porcellus ENSCPOG00000008746
10020 Dipodomys ordii ENSDORG00000003554 9371 Echinops telfairi ENSETEG00000014208
69293 Gasterosteus aculeatus ENSGACG00000009567 9031 Gallus gallus ENSGALG00000026792
9595 Gorilla gorilla ENSGGOG00000003033 7897 Latimeria chalumnae ENSLACG00000008759
9785 Loxodonta africana ENSLAFG00000004607 59463 Myotis lucifugus ENSMLUG00000008836
13616 Monodelphis domestica ENSMODG00000012776 9258 Ornithorhynchus anatinus ENSOANG00000014967
9986 Oryctolagus cuniculus ENSOCUG00000023896 30611 Otolemur garnettii ENSOGAG00000012045
9978 Ochotona princeps ENSOPRG00000005316 8090 Oryzias latipes ENSORLG00000014356
9813 Procavia capensis ENSPCAG00000003284 13735 Pelodiscus sinensis ENSPSIG00000015227
9305 Sarcophilus harrisii ENSSHAG00000008739 43179 Ictidomys tridecemlineatus ENSSTOG00000009576
37347 Tupaia belangeri ENSTBEG00000012271 99883 Tetraodon nigroviridis ENSTNIG00000017264
31033 Takifugu rubripes ENSTRUG00000011729 9478 Tarsius syrichta ENSTSYG00000010010
9739 Tursiops truncatus ENSTTRG00000016110