Basic Information
Gene ID 18741 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Pitx2; Arp1, Brx1, Otlx2, Ptx2, Rgs
Full Name Pituitary homeobox 2
Organism Mus musculus [10090]

Cross Reference
UniProt P97474 UniGene Mm.246804
PDB NULL OMIM NULL
KEGG mmu:18741 UCSC uc008rhv.1

Protein Interactions
DIP NULL
IntAct P97474
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000047359 Gene3D G3DSA:1.10.10.60 IPR009057 66 154 4.10e-29 Homeodomain-like
ENSMUSP00000047359 Pfam PF00046 IPR001356 93 149 2.00e-22 Homeobox domain
ENSMUSP00000047359 Pfam PF03826 IPR003654 281 300 8.50e-10 OAR domain
ENSMUSP00000047359 PIRSF PIRSF000563 IPR016233 1 322 1.90e-207 Homeobox protein Pitx/unc30
ENSMUSP00000047359 ProSitePatterns PS00027 IPR017970 125 148 - Homeobox, conserved site
ENSMUSP00000047359 ProSiteProfiles PS50071 IPR001356 90 150 0.00e-00 Homeobox domain
ENSMUSP00000047359 ProSiteProfiles PS50803 IPR003654 286 299 0.00e-00 OAR domain
ENSMUSP00000047359 SMART SM00389 IPR001356 92 154 2.70e-28 Homeobox domain
ENSMUSP00000047359 SUPERFAMILY SSF46689 IPR009057 85 156 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000047359 PF00046 1.2e-22 Homeobox Homeobox domain
ENSMUSP00000047359 PF03826 8.5e-10 OAR OAR domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000047359 GO:0005634 cellular_component nucleus
ENSMUSP00000047359 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100119888 8090 Oryzias latipes 100144366
6087 Hydra magnipapillata 100211037 34638 Metaseiulus occidentalis 100903936
30611 Otolemur garnettii 100953182 9685 Felis catus 101081219
9595 Gorilla gorilla 101152607 7897 Latimeria chalumnae 102361884
59463 Myotis lucifugus 102439037 13735 Pelodiscus sinensis 102451016
9986 Oryctolagus cuniculus 100009361 13616 Monodelphis domestica 100014280
7029 Acyrthosiphon pisum 100167981 10224 Saccoglossus kowalevskii 100303524
9483 Callithrix jacchus 100415191 28377 Anolis carolinensis 100558975
8128 Oreochromis niloticus 100690583 10029 Cricetulus griseus 100755816
9597 Pan paniscus 100977891 9555 Papio anubis 101001412
39432 Saimiri boliviensis 101042994 31033 Takifugu rubripes 101065143
9669 Mustela putorius furo 101681029 43179 Ictidomys tridecemlineatus 101965650
8083 Xiphophorus maculatus 102237832 7227 Drosophila melanogaster 43664
9598 Pan troglodytes 461438 9615 Canis familiaris 481513
9606 Homo sapiens 5308 10116 Rattus norvegicus 54284
7668 Strongylocentrotus purpuratus 576991 9358 Choloepus hoffmanni ENSCHOG00000011257
7719 Ciona intestinalis ENSCING00000005285 10141 Cavia porcellus ENSCPOG00000009459
51511 Ciona savignyi ENSCSAVG00000005374 7955 Danio rerio ENSDARG00000042785
10020 Dipodomys ordii ENSDORG00000002323 9796 Equus caballus ENSECAG00000014725
9365 Erinaceus europaeus ENSEEUG00000010498 9371 Echinops telfairi ENSETEG00000019990
9031 Gallus gallus ENSGALG00000026881 8049 Gadus morhua ENSGMOG00000017974
9785 Loxodonta africana ENSLAFG00000021420 9315 Macropus eugenii ENSMEUG00000002044
9258 Ornithorhynchus anatinus ENSOANG00000003670 9978 Ochotona princeps ENSOPRG00000011424
9813 Procavia capensis ENSPCAG00000006124 132908 Pteropus vampyrus ENSPVAG00000011068
42254 Sorex araneus ENSSARG00000012726 9823 Sus scrofa ENSSSCG00000009131
37347 Tupaia belangeri ENSTBEG00000016830 99883 Tetraodon nigroviridis ENSTNIG00000013024
9478 Tarsius syrichta ENSTSYG00000002370 9739 Tursiops truncatus ENSTTRG00000015405
30538 Vicugna pacos ENSVPAG00000003542 9913 Bos taurus 508754
7070 Tribolium castaneum 658711 9646 Ailuropoda melanoleuca ENSAMEG00000017884
69293 Gasterosteus aculeatus ENSGACG00000016483 9103 Meleagris gallopavo ENSMGAG00000011019
30608 Microcebus murinus ENSMICG00000002070 61853 Nomascus leucogenys ENSNLEG00000008236
9601 Pongo abelii ENSPPYG00000015003 59729 Taeniopygia guttata ENSTGUG00000004274
8364 Xenopus tropicalis ENSXETG00000013330