
Basic Information | |||
| Gene ID | 196 ; Check Expression Profles ; Check TFs & Targets Binding | ||
| Gene Name | AHR; BHLHE76 | ||
| Full Name | Aryl hydrocarbon receptor | ||
| Organism | Homo sapiens [9606] | ||
Cross Reference | |||
| UniProt | P35869 | UniGene | Hs.171189 |
| PDB | NULL | OMIM | 600253 |
| KEGG | hsa:196 | UCSC | uc011jxz.1 |
Protein Interactions | |
| DIP | DIP-946N |
| IntAct | P35869 |
| MINT | MINT-6597538 |
| STRING | 9606.ENSP00000242057 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
| Protein | Program | Term | IPRS | Start | End | Score | Description |
| NP_001612 | Gene3D | G3DSA:4.10.280.10 | IPR011598 | 37 | 78 | 2.00e-06 | Myc-type, basic helix-loop-helix (bHLH) domain |
| NP_001612 | Pfam | PF00010 | IPR011598 | 37 | 78 | 2.40e-05 | Myc-type, basic helix-loop-helix (bHLH) domain |
| NP_001612 | Pfam | PF00989 | IPR013767 | 114 | 226 | 2.00e-15 | PAS fold |
| NP_001612 | Pfam | PF08447 | IPR013655 | 300 | 382 | 3.60e-12 | PAS fold-3 |
| NP_001612 | ProSiteProfiles | PS50112 | IPR000014 | 111 | 181 | 0.00e-00 | PAS domain |
| NP_001612 | ProSiteProfiles | PS50888 | IPR011598 | 27 | 80 | 0.00e-00 | Myc-type, basic helix-loop-helix (bHLH) domain |
| NP_001612 | SMART | SM00086 | IPR001610 | 348 | 389 | 7.00e-08 | PAC motif |
| NP_001612 | SMART | SM00091 | IPR000014 | 113 | 179 | 2.30e-14 | PAS domain |
| NP_001612 | SMART | SM00091 | IPR000014 | 272 | 342 | 8.30e-05 | PAS domain |
| NP_001612 | SMART | SM00353 | IPR011598 | 34 | 88 | 1.70e-09 | Myc-type, basic helix-loop-helix (bHLH) domain |
| NP_001612 | SUPERFAMILY | SSF47459 | IPR011598 | 37 | 78 | 0.00e-00 | Myc-type, basic helix-loop-helix (bHLH) domain |
| NP_001612 | SUPERFAMILY | SSF55785 | IPR000014 | 122 | 183 | 0.00e-00 | PAS domain |
| NP_001612 | SUPERFAMILY | SSF55785 | IPR000014 | 293 | 388 | 0.00e-00 | PAS domain |
Pfam Annotation | ||||
| Protein | Pfam ID | E.value | Name | Description |
| NP_001612 | PF08447 | 2.7e-18 | PAS_3 | PAS fold |
| NP_001612 | PF00989 | 1.2e-17 | PAS | PAS fold |
| NP_001612 | PF14598 | 1.9e-13 | PAS_11 | PAS domain |
| NP_001612 | PF13426 | 3.5e-07 | PAS_9 | PAS domain |
| NP_001612 | PF00010 | 1.1e-05 | HLH | Helix-loop-helix DNA-binding domain |
| NP_001612 | PF08448 | 0.00068 | PAS_4 | PAS fold |
Gene Ontology Annotation | |||
| Protein | Entry | Name Space | Description |
| NP_001612 | GO:0006351 | biological_process | transcription, DNA-templated |
| NP_001612 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
| NP_001612 | GO:0006366 | biological_process | transcription from RNA polymerase II promoter |
| NP_001612 | GO:0006950 | biological_process | response to stress |
| NP_001612 | GO:0007049 | biological_process | cell cycle |
| NP_001612 | GO:0007165 | biological_process | signal transduction |
| NP_001612 | GO:0009410 | biological_process | response to xenobiotic stimulus |
| NP_001612 | GO:0030522 | biological_process | intracellular receptor signaling pathway |
| NP_001612 | GO:0005634 | cellular_component | nucleus |
| NP_001612 | GO:0005737 | cellular_component | cytoplasm |
| NP_001612 | GO:0003677 | molecular_function | DNA binding |
| NP_001612 | GO:0004871 | molecular_function | signal transducer activity |
| NP_001612 | GO:0004879 | molecular_function | ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity |
| NP_001612 | GO:0046983 | molecular_function | protein dimerization activity |