Basic Information
Gene ID 2078 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name ERG
Full Name Transcriptional regulator ERG
Organism Homo sapiens [9606]

Cross Reference
UniProt P11308 UniGene Hs.473819
PDB 4IRI OMIM 612219
KEGG hsa:2078 UCSC uc021wjd.1

Protein Interactions
DIP DIP-31028N
IntAct P11308
MINT MINT-4910866
STRING 9606.ENSP00000381891

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000414150 Gene3D G3DSA:1.10.10.10 IPR011991 287 418 2.30e-55 Winged helix-turn-helix DNA-binding domain
ENSP00000414150 Gene3D G3DSA:1.10.150.50 IPR013761 129 216 5.80e-33 Sterile alpha motif/pointed domain
ENSP00000414150 Pfam PF00178 IPR000418 317 399 9.80e-40 Ets domain
ENSP00000414150 Pfam PF02198 IPR003118 123 204 4.00e-26 Pointed domain
ENSP00000414150 PRINTS PR00454 IPR000418 318 331 1.30e-30 Ets domain
ENSP00000414150 PRINTS PR00454 IPR000418 342 360 1.30e-30 Ets domain
ENSP00000414150 PRINTS PR00454 IPR000418 361 379 1.30e-30 Ets domain
ENSP00000414150 PRINTS PR00454 IPR000418 380 398 1.30e-30 Ets domain
ENSP00000414150 ProSitePatterns PS00345 IPR000418 320 328 - Ets domain
ENSP00000414150 ProSitePatterns PS00346 IPR000418 364 379 - Ets domain
ENSP00000414150 ProSiteProfiles PS50061 IPR000418 318 398 0.00e-00 Ets domain
ENSP00000414150 ProSiteProfiles PS51433 IPR003118 120 206 0.00e-00 Pointed domain
ENSP00000414150 SMART SM00251 IPR003118 122 206 7.40e-36 Pointed domain
ENSP00000414150 SMART SM00413 IPR000418 317 402 2.60e-60 Ets domain
ENSP00000414150 SUPERFAMILY SSF47769 IPR013761 117 204 0.00e-00 Sterile alpha motif/pointed domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000414150 PF00178 5.6e-40 Ets Ets-domain
ENSP00000414150 PF02198 2.2e-26 SAM_PNT Sterile alpha motif (SAM)/Pointed domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000414150 GO:0006351 biological_process transcription, DNA-templated
ENSP00000414150 GO:0005634 cellular_component nucleus
ENSP00000414150 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000414150 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100051563 7029 Acyrthosiphon pisum 100160630
6087 Hydra magnipapillata 100199698 8364 Xenopus tropicalis 100216056
10224 Saccoglossus kowalevskii 100313592 9103 Meleagris gallopavo 100545465
400682 Amphimedon queenslandica 100634191 30195 Bombus terrestris 100644136
7425 Nasonia vitripennis 100678732 132113 Bombus impatiens 100745321
7463 Apis florea 100870368 143995 Megachile rotundata 100882992
34638 Metaseiulus occidentalis 100903751 9597 Pan paniscus 100969805
9555 Papio anubis 101002077 9669 Mustela putorius furo 101687550
8083 Xiphophorus maculatus 102233945 13735 Pelodiscus sinensis 102452184
10029 Cricetulus griseus 100764178 39432 Saimiri boliviensis 101046309
10090 Mus musculus 13876 6239 Caenorhabditis elegans 173749
7668 Strongylocentrotus purpuratus 397069 9646 Ailuropoda melanoleuca ENSAMEG00000016610
10141 Cavia porcellus ENSCPOG00000007484 9361 Dasypus novemcinctus ENSDNOG00000015727
9371 Echinops telfairi ENSETEG00000015901 69293 Gasterosteus aculeatus ENSGACG00000006586
9031 Gallus gallus ENSGALG00000001161 9595 Gorilla gorilla ENSGGOG00000011391
7897 Latimeria chalumnae ENSLACG00000003340 9785 Loxodonta africana ENSLAFG00000005455
9258 Ornithorhynchus anatinus ENSOANG00000006418 9601 Pongo abelii ENSPPYG00000004052
10116 Rattus norvegicus ENSRNOG00000001652 9305 Sarcophilus harrisii ENSSHAG00000008486
43179 Ictidomys tridecemlineatus ENSSTOG00000025814 9478 Tarsius syrichta ENSTSYG00000000636
7955 Danio rerio 30619 7227 Drosophila melanogaster 38700
9598 Pan troglodytes 473995 7070 Tribolium castaneum 661753
28377 Anolis carolinensis ENSACAG00000016270 9913 Bos taurus ENSBTAG00000011001
9615 Canis familiaris ENSCAFG00000009912 9358 Choloepus hoffmanni ENSCHOG00000009445
7719 Ciona intestinalis ENSCING00000008039 9483 Callithrix jacchus ENSCJAG00000009034
51511 Ciona savignyi ENSCSAVG00000007679 10020 Dipodomys ordii ENSDORG00000012713
9685 Felis catus ENSFCAG00000007485 8049 Gadus morhua ENSGMOG00000013284
9315 Macropus eugenii ENSMEUG00000012591 30608 Microcebus murinus ENSMICG00000003196
59463 Myotis lucifugus ENSMLUG00000009355 9544 Macaca mulatta ENSMMUG00000003141
13616 Monodelphis domestica ENSMODG00000020980 9986 Oryctolagus cuniculus ENSOCUG00000000104
30611 Otolemur garnettii ENSOGAG00000000044 8128 Oreochromis niloticus ENSONIG00000005335
9978 Ochotona princeps ENSOPRG00000009095 8090 Oryzias latipes ENSORLG00000013548
9813 Procavia capensis ENSPCAG00000004227 7757 Petromyzon marinus ENSPMAG00000006439
132908 Pteropus vampyrus ENSPVAG00000016295 42254 Sorex araneus ENSSARG00000012167
9823 Sus scrofa ENSSSCG00000022318 37347 Tupaia belangeri ENSTBEG00000010683
59729 Taeniopygia guttata ENSTGUG00000004998 99883 Tetraodon nigroviridis ENSTNIG00000010320
31033 Takifugu rubripes ENSTRUG00000007690 9739 Tursiops truncatus ENSTTRG00000015358