Basic Information
Gene ID 20788 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Srebf2; Srebp2
Full Name Sterol regulatory element-binding protein 2
Organism Mus musculus [10090]

Cross Reference
UniProt Q3U1N2 UniGene Mm.38016
PDB NULL OMIM NULL
KEGG mmu:20788 UCSC uc011zwr.1

Protein Interactions
DIP NULL
IntAct Q3U1N2
MINT MINT-1739369
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000023100 Gene3D G3DSA:4.10.280.10 IPR011598 316 391 3.60e-24 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMUSP00000023100 Pfam PF00010 IPR011598 320 370 5.60e-16 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMUSP00000023100 ProSitePatterns PS00290 IPR003006 911 917 - Immunoglobulin/major histocompatibility complex, conserved site
ENSMUSP00000023100 ProSiteProfiles PS50888 IPR011598 319 369 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMUSP00000023100 SMART SM00353 IPR011598 325 375 1.20e-17 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMUSP00000023100 SUPERFAMILY SSF47459 IPR011598 316 386 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000023100 PF00010 2.2e-16 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000023100 GO:0006351 biological_process transcription, DNA-templated
ENSMUSP00000023100 GO:0006629 biological_process lipid metabolic process
ENSMUSP00000023100 GO:0008203 biological_process cholesterol metabolic process
ENSMUSP00000023100 GO:0000139 cellular_component Golgi membrane
ENSMUSP00000023100 GO:0005634 cellular_component nucleus
ENSMUSP00000023100 GO:0005783 cellular_component endoplasmic reticulum
ENSMUSP00000023100 GO:0005789 cellular_component endoplasmic reticulum membrane
ENSMUSP00000023100 GO:0012507 cellular_component ER to Golgi transport vesicle membrane
ENSMUSP00000023100 GO:0016021 cellular_component integral component of membrane
ENSMUSP00000023100 GO:0003677 molecular_function DNA binding
ENSMUSP00000023100 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100164413 30195 Bombus terrestris 100652148
10029 Cricetulus griseus 100689017 8128 Oreochromis niloticus 100692789
143995 Megachile rotundata 100875972 9597 Pan paniscus 100989920
9555 Papio anubis 101008423 28377 Anolis carolinensis 100552463
7463 Apis florea 100867330 39432 Saimiri boliviensis 101030018
9595 Gorilla gorilla 101131710 9646 Ailuropoda melanoleuca ENSAMEG00000015506
9365 Erinaceus europaeus ENSEEUG00000003437 9371 Echinops telfairi ENSETEG00000000459
69293 Gasterosteus aculeatus ENSGACG00000007259 9031 Gallus gallus ENSGALG00000011916
9315 Macropus eugenii ENSMEUG00000011986 13616 Monodelphis domestica ENSMODG00000016612
9258 Ornithorhynchus anatinus ENSOANG00000002461 9986 Oryctolagus cuniculus ENSOCUG00000003178
30611 Otolemur garnettii ENSOGAG00000014736 9978 Ochotona princeps ENSOPRG00000008570
9601 Pongo abelii ENSPPYG00000011880 13735 Pelodiscus sinensis ENSPSIG00000014746
9598 Pan troglodytes ENSPTRG00000014439 132908 Pteropus vampyrus ENSPVAG00000001177
10116 Rattus norvegicus ENSRNOG00000007400 37347 Tupaia belangeri ENSTBEG00000016542
59729 Taeniopygia guttata ENSTGUG00000009772 31033 Takifugu rubripes ENSTRUG00000007413
30538 Vicugna pacos ENSVPAG00000001280 8083 Xiphophorus maculatus ENSXMAG00000003080
7227 Drosophila melanogaster 40155 9615 Canis familiaris 481228
7668 Strongylocentrotus purpuratus 590876 9913 Bos taurus ENSBTAG00000014265
9483 Callithrix jacchus ENSCJAG00000002378 10141 Cavia porcellus ENSCPOG00000013199
51511 Ciona savignyi ENSCSAVG00000010155 10020 Dipodomys ordii ENSDORG00000000691
9796 Equus caballus ENSECAG00000024608 9685 Felis catus ENSFCAG00000014289
9785 Loxodonta africana ENSLAFG00000005791 9103 Meleagris gallopavo ENSMGAG00000012074
30608 Microcebus murinus ENSMICG00000000913 59463 Myotis lucifugus ENSMLUG00000002549
9544 Macaca mulatta ENSMMUG00000003357 9669 Mustela putorius furo ENSMPUG00000016372
8090 Oryzias latipes ENSORLG00000014672 9813 Procavia capensis ENSPCAG00000006497
42254 Sorex araneus ENSSARG00000006597 9305 Sarcophilus harrisii ENSSHAG00000011682
9823 Sus scrofa ENSSSCG00000026092 43179 Ictidomys tridecemlineatus ENSSTOG00000012916
99883 Tetraodon nigroviridis ENSTNIG00000010835 9739 Tursiops truncatus ENSTTRG00000017350