Basic Information
Gene ID 20846 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Stat1; mCG_123683
Full Name Signal transducer and activator of transcription
Organism Mus musculus [10090]

Cross Reference
UniProt Q8C3V4 UniGene Mm.487336
PDB NULL OMIM NULL
KEGG mmu:20846 UCSC uc007ayc.2

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_001192242 Gene3D G3DSA:1.10.238.10 IPR011992 467 587 5.50e-51 EF-hand domain pair
NP_001192242 Gene3D G3DSA:1.10.532.10 IPR013799 1 121 8.00e-47 STAT transcription factor, protein interaction
NP_001192242 Gene3D G3DSA:1.20.1050.20 IPR013800 137 317 3.60e-66 STAT transcription factor, all-alpha
NP_001192242 Gene3D G3DSA:2.60.40.630 IPR012345 318 466 1.90e-63 STAT transcription factor, DNA-binding, subdomain
NP_001192242 Gene3D G3DSA:3.30.505.10 IPR000980 588 717 4.50e-53 SH2 domain
NP_001192242 PANTHER PTHR11801 IPR001217 2 747 0.00e-00 Transcription factor STAT
NP_001192242 Pfam PF00017 IPR000980 584 644 6.90e-09 SH2 domain
NP_001192242 Pfam PF01017 IPR013800 137 315 3.70e-62 STAT transcription factor, all-alpha
NP_001192242 Pfam PF02864 IPR013801 317 573 3.90e-115 STAT transcription factor, DNA-binding
NP_001192242 Pfam PF02865 IPR013799 2 121 1.20e-43 STAT transcription factor, protein interaction
NP_001192242 Pfam PF12162 IPR022752 721 745 3.30e-12 Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal
NP_001192242 ProSiteProfiles PS50001 IPR000980 579 676 0.00e-00 SH2 domain
NP_001192242 SMART SM00252 IPR000980 577 693 8.00e-04 SH2 domain
NP_001192242 SMART SM00964 IPR013799 2 122 1.50e-65 STAT transcription factor, protein interaction
NP_001192242 SUPERFAMILY SSF47655 IPR015988 134 317 0.00e-00 STAT transcription factor, coiled coil
NP_001192242 SUPERFAMILY SSF48092 IPR013799 1 121 0.00e-00 STAT transcription factor, protein interaction
NP_001192242 SUPERFAMILY SSF49417 IPR008967 317 574 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_001192242 PF01017 0 STAT_alpha STAT protein, all-alpha domain
NP_001192242 PF02864 0 STAT_bind STAT protein, DNA binding domain
NP_001192242 PF02865 1.20512e-43 STAT_int STAT protein, protein interaction domain
NP_001192242 PF12162 1.4e-12 STAT1_TAZ2bind STAT1 TAZ2 binding domain
NP_001192242 PF00017 1.3e-09 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
NP_001192242 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
NP_001192242 GO:0045893 biological_process positive regulation of transcription, DNA-templated
NP_001192242 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
NP_001192242 GO:0005634 cellular_component nucleus
NP_001192242 GO:0005737 cellular_component cytoplasm
NP_001192242 GO:0003677 molecular_function DNA binding
NP_001192242 GO:0004871 molecular_function signal transducer activity
NP_001192242 GO:0005509 molecular_function calcium ion binding
NP_001192242 GO:0019901 molecular_function protein kinase binding
NP_001192242 GO:0043565 molecular_function sequence-specific DNA binding